Modeling resilience to schizophrenia in genetically modified mice: a novel approach to drug discovery

Andra Mihali; Shreya Subramani; Genevieve Kaunitz; Stephen Rayport; Inna Gaisler-Salomon

doi:10.1586/ern.12.60

Modeling resilience to schizophrenia in genetically modified mice: a novel approach to drug discovery

Expert Review of Neurotherapeutics ◽

10.1586/ern.12.60 ◽

2012 ◽

Vol 12 (7) ◽

pp. 785-799 ◽

Cited By ~ 13

Author(s):

Andra Mihali ◽

Shreya Subramani ◽

Genevieve Kaunitz ◽

Stephen Rayport ◽

Inna Gaisler-Salomon

Keyword(s):

Drug Discovery ◽

Genetically Modified ◽

Novel Approach ◽

Genetically Modified Mice

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A Loop‐Based and AGO‐Incorporated Virtual Screening Model Targeting AGO‐Mediated miRNA–mRNA Interactions for Drug Discovery to Rescue Bone Phenotype in Genetically Modified Mice

Advanced Science ◽

10.1002/advs.201903451 ◽

2020 ◽

Vol 7 (13) ◽

pp. 1903451 ◽

Cited By ~ 1

Author(s):

Zhenjian Zhuo ◽

Youyang Wan ◽

Daogang Guan ◽

Shuaijian Ni ◽

Luyao Wang ◽

...

Keyword(s):

Drug Discovery ◽

Virtual Screening ◽

Genetically Modified ◽

Bone Phenotype ◽

Screening Model ◽

Genetically Modified Mice

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Genetically modified mice for the study of apolipoprotein B

The Journal of Lipid Research ◽

10.1016/s0022-2275(20)32560-8 ◽

1998 ◽

Vol 39 (4) ◽

pp. 703-723

Author(s):

Edward Kim ◽

Stephen G. Young

Keyword(s):

Apolipoprotein B ◽

Genetically Modified ◽

Genetically Modified Mice

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Inverse Relationship of Skeletal Muscle Glycogen from Wild-Type and Genetically Modified Mice to Their Phosphorylase a Activity

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.2001.6292 ◽

2002 ◽

Vol 290 (2) ◽

pp. 874-877 ◽

Cited By ~ 1

Author(s):

Louis H. Schliselfeld ◽

Moris J. Danon

Keyword(s):

Skeletal Muscle ◽

Muscle Glycogen ◽

Inverse Relationship ◽

Genetically Modified ◽

Wild Type ◽

Skeletal Muscle Glycogen ◽

Genetically Modified Mice ◽

Relationship Of

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Generating genetically modified mice using CRISPR/Cas-mediated genome engineering

Nature Protocols ◽

10.1038/nprot.2014.134 ◽

2014 ◽

Vol 9 (8) ◽

pp. 1956-1968 ◽

Cited By ~ 292

Author(s):

Hui Yang ◽

Haoyi Wang ◽

Rudolf Jaenisch

Keyword(s):

Genome Engineering ◽

Genetically Modified ◽

Genetically Modified Mice

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Behavioral Analysis of Genetically Modified Mice Indicates Essential Roles of Neurosteroidal Estrogen

Frontiers in Endocrinology ◽

10.3389/fendo.2011.00040 ◽

2011 ◽

Vol 2 ◽

Cited By ~ 12

Author(s):

Shin-Ichiro Honda ◽

Toru Wakatsuki ◽

Nobuhiro Harada

Keyword(s):

Genetically Modified ◽

Behavioral Analysis ◽

Genetically Modified Mice

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Protein kinase C isozymes as regulators of sensitivity to and self-administration of drugs of abuse-studies with genetically modified mice

Behavioural Pharmacology ◽

10.1097/fbp.0b013e32833d8bb7 ◽

2010 ◽

Vol 21 (5-6) ◽

pp. 493-499 ◽

Cited By ~ 14

Author(s):

Michael Foster Olive ◽

Philip M. Newton

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Drugs Of Abuse ◽

Genetically Modified ◽

Self Administration ◽

Kinase C ◽

Genetically Modified Mice

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[P2-143]: SCREENING FOR INHIBITORS OF APOE4-CATALYZED Aβ OLIGOMER/FILAMENT FORMATION: A NOVEL APPROACH TO ALZHEIMER's DISEASE DRUG DISCOVERY

Alzheimer s & Dementia ◽

10.1016/j.jalz.2017.06.793 ◽

2017 ◽

Vol 13 (7S_Part_13) ◽

pp. P662-P663

Author(s):

Christina M. Coughlan ◽

Athena Wang ◽

Lisa Viltz ◽

Heidi J. Chial ◽

Huntington Potter

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Drug Discovery ◽

Filament Formation ◽

Novel Approach ◽

Aβ Oligomer

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Abstract 605: Identification of Differential Roles of Microrna-33a and -33b During Atherosclerosis Progression with Genetically Modified Mice

Circulation Research ◽

10.1161/res.125.suppl_1.605 ◽

2019 ◽

Vol 125 (Suppl_1) ◽

Author(s):

Takahiro Horie ◽

Satoshi Koyama ◽

Yui Miyasaka ◽

Takeshi Kimura ◽

Koh Ono

Keyword(s):

Genetically Modified ◽

Atherosclerosis Progression ◽

Genetically Modified Mice

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Generation and Analysis of Genetically Modified Mice

Handbook of Laboratory Animal Science ◽

10.1201/9780429439964-11 ◽

2021 ◽

pp. 225-236

Author(s):

Cord Brakebusch

Keyword(s):

Genetically Modified ◽

Genetically Modified Mice

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Human cytomegalovirus IE2 protein regulates macrophage-mediated immune escape by upregulating GRB2 expression in UL122 genetically modified mice

BioScience Trends ◽

10.5582/bst.2019.01197 ◽

2019 ◽

Vol 13 (6) ◽

pp. 502-509 ◽

Cited By ~ 1

Author(s):

Yanan Yang ◽

Guohua Ren ◽

Zhifei Wang ◽

Bin Wang

Keyword(s):

Human Cytomegalovirus ◽

Immune Escape ◽

Genetically Modified ◽

Genetically Modified Mice

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