Biological vascular grafts for hemodialysis access

2013 ◽  
Vol 10 (2) ◽  
pp. 171-175 ◽  
Author(s):  
Mohammad A Hossain ◽  
Adam E Frampton ◽  
Tina T Chowdhury ◽  
Mohamed Morsy
2012 ◽  
Vol 13 (3) ◽  
pp. 279-285 ◽  
Author(s):  
Luigi Tazza ◽  
Franco Galli ◽  
Salvatore Mandolfo ◽  
Giacomo Forneris ◽  
Michele Di Dio ◽  
...  

1990 ◽  
Vol 1 (1) ◽  
pp. 11-14 ◽  
Author(s):  
Geoffrey Taylor ◽  
Teresa Kirkland ◽  
Peter Hamilton

As part of an ongoing prospective survey of nosocomial bacteremias, patients developing bacteremia while undergoing in-centre hemodialysis were observed over a 23 month period. Thirty-six episodes of bacteremia occurred in 30 patients: every episode was directly attributable to hemodialysis. In 28 of the 36 episodes (78%), there was evidence of inflammation with or without drainage of pus at the hemodialysis access site.Staphylococcus aureusaccounted for 76% of the bacteremic isolates. Patients hemodialyzing through central venous catheters had a far higher incidence of bacteremia (0.01 per dialysis run) than patients hemodialyzing through vascular grafts (0.0005 per dialysis run).


2017 ◽  
Vol 66 (6) ◽  
pp. 1792-1797 ◽  
Author(s):  
John D. Kakisis ◽  
Constantine Antonopoulos ◽  
George Mantas ◽  
Evaggelos Alexiou ◽  
Konstantina Katseni ◽  
...  

2017 ◽  
Vol 31 (3) ◽  
pp. 192-200 ◽  
Author(s):  
Karen Tatiana Valencia Rivero ◽  
Juliana Jaramillo Escobar ◽  
Sergio David Galvis Forero ◽  
Maria Clara Miranda Saldaña ◽  
Rocío del Pilar López Panqueva ◽  
...  

Author(s):  
E.J. Prendiville ◽  
S. Laliberté Verdon ◽  
K. E. Gould ◽  
K. Ramberg ◽  
R. J. Connolly ◽  
...  

Endothelial cell (EC) seeding is postulated as a mechanism of improving patency in small caliber vascular grafts. However the majority of seeded EC are lost within 24 hours of restoration of blood flow in previous canine studies . We postulate that the cells have insufficient time to fully develop their attachment to the graft surface prior to exposure to hemodynamic stress. We allowed EC to incubate on fibronectin-coated ePTFE grafts for four different time periods after seeding and measured EC retention after perfusion in a canine ex vivo shunt circuit.Autologous canine EC, were enzymatically harvested, grown to confluence, and labeled with 30 μCi 111 Indium-oxine/80 cm 2 flask. Four groups of 5 cm x 4 mm ID ePTFE vascular prostheses were coated with 1.5 μg/cm.2 human fibronectin, and seeded with 1.5 x 105 EC/ cm.2. After seeding grafts in Group 1 were incubated in complete growth medium for 90 minutes, Group 2 were incubated for 24 hours, Group 3 for 72 hours and Group 4 for 6 days. Grafts were then placed in the canine ex vivo circuit, constructed between femoral artery and vein, and subjected to blood flow of 75 ml per minute for 6 hours. Continuous counting of γ-activity was made possible by placing the seeded graft inside the γ-counter detection crystal for the duration of perfusion. EC retention data after 30 minutes, 2 hours and 6 hours of flow are shown in the table.


1994 ◽  
Vol 27 (1) ◽  
pp. 91-123 ◽  
Author(s):  
Roy M. Fujitani ◽  
David L. Cull ◽  
David L. Dawson

1985 ◽  
Vol 53 (03) ◽  
pp. 423-427 ◽  
Author(s):  
Stephen R Hanson ◽  
Laurence A Harker

SummarySuloctidil has been evaluated in the baboon for its antithrombotic efficacy using models of both acute and chronic arterial thrombogenesis. Acute thrombus formation was initiated by Dacron vascular grafts inserted as extension segments into chronic arteriovenous shunts. 111In-platelet deposition was measured by scintillation camera imaging for one hour. The results after oral administration of suloctidil (100 mg/kg/d in two divided doses) were not different from control studies. Moreover, concurrent heparin anticoagulation did not affect 111In-platelet deposition compared with control data. In contrast, ticlopidine (20 mg/ kg/d) significantly decreased platelet deposition that was reduced further by the addition of heparin.Chronic arterial-thromboembolism was initiated by segments of polyurethane (Biomer) cannula introduced into chronic arteriovenous shunts. Thrombus formation by the polyurethane cannula was measured as 111In-platelet turnover (corrected for removal of senescent platelets). Cannula platelet consumption was unaffected by suloctidil (20 mg/kg/d given in two divided doses for two days preceding and throughout the period of platelet survival measurement). In contrast, dipyridamole (10 mg/ kg/d) and sulfinpyrazone (100 mg/kg/d) completely interrupted cannula platelet consumption.We conclude that suloctidil probably has little or no effect on platelet-dependent thrombus formation.


2007 ◽  
Vol 55 (S 1) ◽  
Author(s):  
CD Etz ◽  
TM Homann ◽  
D Silovitz ◽  
M Lühr ◽  
CA Bodian ◽  
...  

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