Carbon nanotubes in scaffolds for tissue engineering

2009 ◽  
Vol 6 (5) ◽  
pp. 499-505 ◽  
Author(s):  
Sharon L Edwards ◽  
Jerome A Werkmeister ◽  
John AM Ramshaw
Keyword(s):  
Carbon Nanotubes ◽  
Tissue Engineering

Enhanced osteogenic potential of unzipped carbon nanotubes for tissue engineering

2021 ◽  
Author(s):  
Dinesh K. Patel ◽  
Sayan Deb Dutta ◽  
Keya Ganguly ◽  
Jin‐Woo Kim ◽  
Ki‐Taek Lim
Keyword(s):  
Carbon Nanotubes ◽  
Tissue Engineering ◽  
Osteogenic Potential

Application of Carbon Nanotubes in Cartilage Tissue Engineering

2008 ◽  
Author(s):  
Nadeen O. Chahine ◽  
Nicole M. Collette ◽  
Heather Thompson ◽  
Gabriela G. Loots
Keyword(s):  
Carbon Nanotubes ◽  
Tissue Engineering ◽  
Cartilage Tissue Engineering ◽  
Cellular Systems ◽  
Cellular Growth ◽  
Cartilage Tissue ◽  
Chondrocyte Viability ◽  
Structural Reinforcement ◽  
Surgical Implants ◽  
Novel Material

Carbon nanotubes (CNTs) are cylindrical allotropes of carbon that are nanometers in diameter and posses unique physical properties, positioning them as ideal materials for studying physiology at a single cell level. CNTs have the potential to become a very important component of medical therapeutics, likely acting as (a) drug delivery system [1], (b) existing as an interfacial layer in surgical implants [2,3], or (c) acting as scaffolding in tissue engineering [4,8]. While some studies have explored the use of CNTs as a novel material in regenerative medicine, they have not yet been fully evaluated in cellular systems. One major limitation of CNTs that must be overcome is their inherent cytotoxicity. The goal of this study is to assess the long-term biocompatibility of CNTs for chondrocyte growth. We hypothesize that CNT-based material in tissue engineering can provide an improved molecular sized substrate for stimulation of cellular growth, and structural reinforcement of the scaffold mechanical properties. Here we present data on the effects of CNTs on chondrocyte viability and biochemical deposition examined in composite materials of hydrogels + CNTs mixtures. Also, the effects of CNTs surface functionalization with polyethlyne glycol (PEG) or carboxyl groups (COOH) were examined.

scholarly journals Carbon nanotubes and their polymeric composites: the applications in tissue engineering

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Boyang Huang
Keyword(s):  
Carbon Nanotubes ◽  
Electrical Conductivity ◽  
Tissue Engineering ◽  
Bone Tissue ◽  
Biomedical Applications ◽  
Chemical Properties ◽  
Polymeric Composites ◽  
Biological Properties ◽  
Engineering Applications ◽  
Toxicity Effects

Abstract Carbon nanotubes (CNTs), with unique graphitic structure, superior mechanical, electrical, optical and biological properties, has attracted more and more interests in biomedical applications, including gene/drug delivery, bioimaging, biosensor and tissue engineering. In this review, we focus on the role of CNTs and their polymeric composites in tissue engineering applications, with emphasis on their usages in the nerve, cardiac and bone tissue regenerations. The intrinsic natures of CNTs including their physical and chemical properties are first introduced, explaining the structure effects on CNTs electrical conductivity and various functionalization of CNTs to improve their hydrophobic characteristics. Biosafety issues of CNTs are also discussed in detail including the potential reasons to induce the toxicity and their potential strategies to minimise the toxicity effects. Several processing strategies including solution-based processing, polymerization, melt-based processing and grafting methods are presented to show the 2D/3D construct formations using the polymeric composite containing CNTs. For the sake of improving mechanical, electrical and biological properties and minimising the potential toxicity effects, recent advances using polymer/CNT composite the tissue engineering applications are displayed and they are mainly used in the neural tissue (to improve electrical conductivity and biological properties), cardiac tissue (to improve electrical, elastic properties and biological properties) and bone tissue (to improve mechanical properties and biological properties). Current limitations of CNTs in the tissue engineering are discussed and the corresponded future prospective are also provided. Overall, this review indicates that CNTs are promising “next-generation” materials for future biomedical applications.

Carbon nanotube doped pericardial matrix derived electroconductive biohybrid hydrogel for cardiac tissue engineering

2019 ◽  
Vol 7 (9) ◽  
pp. 3906-3917 ◽  
Author(s):  
Kaveh Roshanbinfar ◽  
Zahra Mohammadi ◽  
Abdorreza Sheikh-Mahdi Mesgar ◽  
Mohammad Mehdi Dehghan ◽  
Oommen P. Oommen ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Tissue Engineering ◽  
Stem Cell ◽  
Carbon Nanotube ◽  
Cardiac Tissue ◽  
Cardiac Tissue Engineering ◽  
Promising Material ◽  
Positively Charged

Biohybrid hydrogels consisting of solubilized nanostructured pericardial matrix and electroconductive positively charged hydrazide-conjugated carbon nanotubes provide a promising material for stem cell-based cardiac tissue engineering.

Fabrication of biocompatible nanohybrid shish-kebab-structured carbon nanotubes with a mussel-inspired layer

RSC Advances ◽  
2016 ◽  
Vol 6 (103) ◽  
pp. 101660-101670 ◽  
Author(s):  
Tong Wu ◽  
Jin Sha ◽  
Yiyan Peng ◽  
Xin Chen ◽  
Linsheng Xie ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Tissue Engineering ◽  
First Report ◽  
Coated Carbon

The first report investigating the biocompatibility of the (polydopamine coated) carbon nanotubes/polymer nanohybrid shish-kebab structure for tissue engineering.

Porous and strong three-dimensional carbon nanotube coated ceramic scaffolds for tissue engineering

2015 ◽  
Vol 3 (42) ◽  
pp. 8337-8347 ◽  
Author(s):  
P. Newman ◽  
Z. Lu ◽  
S. I. Roohani-Esfahani ◽  
T. L. Church ◽  
M. Biro ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Tissue Engineering ◽  
Carbon Nanotube ◽  
Three Dimensional ◽  
Biological Properties ◽  
Porous Structures ◽  
High Quality

A method to coat high-quality uniform coatings of carbon nanotubes throughout 3D porous structures is developed. Testing of their physical and biological properties demonstrate their potential for application in tissue engineering.

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