Current management of colorectal hepatic metastasis

2009 ◽  
Vol 3 (2) ◽  
pp. 131-144 ◽  
Author(s):  
Skye C Mayo ◽  
Timothy M Pawlik
Keyword(s):  
Hepatic Metastasis ◽  
Current Management ◽  
Colorectal Hepatic Metastasis

scholarly journals METACHRONOUS COLORECTAL LIVER METASTASES HAS BETTER PROGNOSIS - IS IT TRUE?

2018 ◽  
Vol 55 (3) ◽  
pp. 258-263 ◽  
Author(s):  
Claudemiro QUIREZE JUNIOR ◽  
Andressa Machado Santana BRASIL ◽  
Lúcio Kenny MORAIS ◽  
Edmond Raymond Le CAMPION ◽  
Eliseu José Fleury TAVEIRA ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Overall Survival ◽  
Liver Metastases ◽  
Hepatic Metastasis ◽  
Colorectal Liver Metastases ◽  
Public Health Problem ◽  
Recurrence Free Survival ◽  
Free Survival ◽  
The Mean ◽  
Colorectal Hepatic Metastasis

ABSTRACT BACKGROUND: Liver metastases from colorectal cancer are an important public health problem due to the increasing incidence of colorectal cancer worldwide. Synchronous colorectal liver metastasis has been associated with worse survival, but this prognosis is controversial. OBJECTIVE: The objective of this study was to evaluate the recurrence-free survival and overall survival between groups of patients with metachronous and synchronous colorectal hepatic metastasis. METHODS: This was a retrospective analysis of medical records of patients with colorectal liver metastases seen from 2013 to 2016, divided into a metachronous and a synchronous group. The Cox regression model and the Kaplan-Meier method with log-rank test were used to compare survival between groups. RESULTS: The mean recurrence-free survival was 9.75 months and 50% at 1 year in the metachronous group and 19.73 months and 63.3% at 1 year in the synchronous group. The mean overall survival was 20.00 months and 6.2% at 3 years in the metachronous group and 30.39 months and 31.6% at 3 years in the synchronous group. Patients with metachronous hepatic metastasis presented worse overall survival in multivariate analysis. The use of biological drugs combined with chemotherapy was related to the best overall survival prognosis. CONCLUSION: Metachronous colorectal hepatic metastasis was associated with a worse prognosis for overall survival. There was no difference in recurrence-free survival between metachronous and synchronous metastases.

Peri-operative chemotherapy for patients with resectable colorectal hepatic metastasis: A meta-analysis

2015 ◽  
Vol 41 (9) ◽  
pp. 1197-1203 ◽  
Author(s):  
Z.-M. Wang ◽  
Y.-Y. Chen ◽  
F.-F. Chen ◽  
S.-Y. Wang ◽  
B. Xiong
Keyword(s):  
Hepatic Metastasis ◽  
Meta Analysis ◽  
Colorectal Hepatic Metastasis

Tumor Vascular Microenvironment of Colorectal Hepatic Metastasis and Chemotherapy Response

2021 ◽  
Vol 41 (9) ◽  
pp. 4505-4513
Author(s):  
HIROTAKA OKAMOTO ◽  
SHUGO SHIBA ◽  
HIROSHI IINO ◽  
MAKOTO SUDOH ◽  
DAISUKE ICHIKAWA
Keyword(s):  
Hepatic Metastasis ◽  
Chemotherapy Response ◽  
Colorectal Hepatic Metastasis

scholarly journals Short Time to Recurrence After Hepatic Resection Correlates with Poor Prognosis in Colorectal Hepatic Metastasis

2006 ◽  
Vol 36 (6) ◽  
pp. 368-375 ◽  
Author(s):  
Shinichiro Takahashi ◽  
Masaru Konishi ◽  
Toshio Nakagohri ◽  
Naoto Gotohda ◽  
Norio Saito ◽  
...  
Keyword(s):  
Hepatic Resection ◽  
Hepatic Metastasis ◽  
Poor Prognosis ◽  
Time To Recurrence ◽  
Short Time ◽  
Colorectal Hepatic Metastasis
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