scholarly journals Cardiomyopathy etiologies and survival analysis in a cohort of patients with chronic heart failure

2017 ◽  
Vol 12 (9-10) ◽  
pp. 355-356
Author(s):  
Gloria Lekšić ◽  
Jasmina Hranjec ◽  
Marijan Pašalić ◽  
Boško Skorić ◽  
Jure Samardžić ◽  
...  
Keyword(s):  
Heart Failure ◽  
Survival Analysis ◽  
Chronic Heart Failure

scholarly journals Application of Extreme Learning Machine in the Survival Analysis of Chronic Heart Failure Patients With High Percentage of Censored Survival Time

2021 ◽  
Vol 8 ◽  
Author(s):  
Hong Yang ◽  
Jing Tian ◽  
Bingxia Meng ◽  
Ke Wang ◽  
Chu Zheng ◽  
...  
Keyword(s):  
Heart Failure ◽  
Survival Analysis ◽  
Chronic Heart Failure ◽  
Survival Time ◽  
Extreme Learning Machine ◽  
Cox Model ◽  
Prediction Performance ◽  
Brier Score ◽  
Model Based ◽  
Learning Machine

Objective: To explore the application of the Cox model based on extreme learning machine in the survival analysis of patients with chronic heart failure.Methods: The medical records of 5,279 inpatients diagnosed with chronic heart failure in two grade 3 and first-class hospitals in Taiyuan from 2014 to 2019 were collected; with death as the outcome and after the feature selection, the Lasso Cox, random survival forest (RSF), and the Cox model based on extreme learning machine (ELM Cox) were constructed for survival analysis and prediction; the prediction performance of the three models was explored based on simulated data with three censoring ratios of 25, 50, and 75%.Results: Simulation results showed that the prediction performance of the three models decreased with increasing censoring proportion, and the ELM Cox model performed best overall; the ELM Cox model constructed with 21 highly influential survival predictors screened from actual chronic heart failure data showed the best performance with C-index and Integrated Brier Score (IBS) of 0.775(0.755, 0.802) and 0.166(0.150, 0.182), respectively.Conclusion: The ELM Cox model showed good discrimination performance in the survival analysis of patients with chronic heart failure; it performs consistently for data with a high proportion of censored survival time; therefore, the model could help physicians identify patients at high risk of poor prognosis and target therapeutic measures to patients as early as possible.

689 The activation of the NF-kappaB system in chronic heart failure

2003 ◽  
Vol 2 (1) ◽  
pp. 141-142
Author(s):  
E JANKOWSKA ◽  
A CZARNY ◽  
E ZACZYNSKA ◽  
W BANASIAK ◽  
S ANKER ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Nf Kappab
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