scholarly journals Diastolic function in patients with hypertrophic cardiomyopathy and left ventricle outflow tract obstruction after alcohol septal ablation.

2015 ◽  
Vol 10 (3-4) ◽  
pp. 61-61
Author(s):  
Irena Ivanac Vranesic ◽  
Karlo Golubic ◽  
Eduard Margetic ◽  
Petra Angebrandt ◽  
Vojtjeh Brida ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Left Ventricle ◽  
Diastolic Function ◽  
Outflow Tract ◽  
Alcohol Septal Ablation

scholarly journals Evaluating of the effectiveness and safety of the reproduced selective β1-blocker without intrinsic sympathomimetic activity Bidop® in patients with hypertrophic cardiomyopathy

2016 ◽  
Vol 13 (2) ◽  
pp. 88-90
Author(s):  
L I Feiskhanova ◽  
A A Malov
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Left Ventricle ◽  
Diastolic Function ◽  
Interventricular Septum ◽  
Outflow Tract ◽  
Intrinsic Sympathomimetic Activity ◽  
Active Relaxation

The article assesses the effectiveness of therapy generics Bidop® production of Gedeon Richter (Hungary), designated to improve diastolic function, and treatment of heart failureof patients with hypertrophic cardiomyopathy with predominant hypertrophy of the interventricular septum and symmetrical concentric shape in the absence of obstruction of outflow tract of the left ventricle (LV). The effect of the presence of zones of intramyocardial fibrosis hypertrophied LV departments identified through MRI delayed contrast, to the process of active relaxation.

scholarly journals The results of alcoholic septal ablation in the treatment of hypertrophic cardiomyopathy

2020 ◽  
pp. 44-49
Author(s):  
B.M. Todurov ◽  
◽  
G.I. Kovtun ◽  
A.V. Khokhlov ◽  
O.V. Pantazi ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Hypertrophic Cardiomyopathy ◽  
Left Ventricular Outflow Tract ◽  
Young Patients ◽  
Ventricular Outflow Tract ◽  
Hypertrophic Obstructive Cardiomyopathy ◽  
Left Ventricular ◽  
Outflow Tract ◽  
Alcohol Septal Ablation ◽  
Left Ventricular Outflow

Hypertrophic obstructive cardiomyopathy іs a relatively common condition and one of the most common causes of sudden cardiac death in young age. One of the options for the surgical treatment of this pathology is septal myoectomy, which has been the gold standard for decades. However, despite this, surgical treatment is intended for young patients with a low risk of postoperative complications, while patients with concomitant diseases and a higher surgical risk require alternative treatment. Today, alcohol septal ablation is considered an effective, minimally invasive method for treating hypertrophic obstructive cardiomyopathy in patients with a left ventricular outflow tract gradient ≥ 50 mm Hg. The article presents the experience of using alcohol septal ablation in 57 patients with obstruction of the left ventricular outflow tract. Key words: alcoholic septal ablation, hypertrophic cardiomyopathy, left ventricular outflow tract obstruction.

scholarly journals Hybrid telerehabilitation in patients with hypertrophic cardiomyopathy without left ventricular outflow tract obstruction and preserved left ventricular ejection fraction-the randomised clinical trial

2021 ◽  
Vol 2 (4) ◽  
Author(s):  
K Sadowski ◽  
R Piotrowicz ◽  
M Klopotowski ◽  
J Wolszakiewicz ◽  
A Lech ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Left Ventricle ◽  
Ejection Fraction ◽  
Group Analysis ◽  
Left Ventricular ◽  
Outflow Tract ◽  
Left Ventricular Ejection ◽  
Nordic Walking ◽  
Home Based ◽  
Lv Ejection Fraction

Abstract Background Hypertrophic cardiomyopathy (HCM) is the most common hereditary heart disease, and its diagnosis is often associated with limited physical activity. Little is known about cardiac rehabilitation programs for patients with HCM. Therefore the novel hybrid cardiac telerehabilitation (HCTR) model consisting of hospital-based rehabilitation and home-based telemonitored rehabilitation might be an option to improve physical capacity in patients with HCM. Purpose To evaluate the safety, effectiveness and adherence to HCTR in patients with HCM without the left ventricle (LV) outflow tract obstruction and preserved LV ejection fraction. Methods The study group comprised 60 patients with HCM (51.1±13.3 years; NYHA II-III; LV ejection fraction 66.1±6.9%). Patients were randomised (1:1) to either HCTR program (hospital-based rehabilitation [1 month] based on cycloergometer training and home-based telemonitored rehabilitation [2 months] based on Nordic walking, five times a week, at 40–70% of maximal estimated heart rate) - training group (TG), or to a control group (CG). All patients had implantable cardioverter-defibrillator. In order to perform home-based telemonitored rehabilitation, a special device was used which enabled patients to: (1) do Nordic walking training according to a preprogrammed plan, (2) record and send electrocardiograms (ECGs) via mobile phone network to the monitoring centre. The moments of automatic ECGs registration were pre-set and coordinated with exercise training. The effectiveness of HCTR was assessed by changes - delta (Δ) in duration (t) of the workload, peak oxygen consumption (pVO2) in cardiopulmonary exercise test, 6-minute walking test distance (6-MWT) as a result of comparing t (s), pVO2 (ml/kg/min), 6-MWT (m) from the beginning and the end of the program. Results Safety of HCTR. Neither death nor other serious adverse events occurred during HCTR. We did not observe any ICDs intervention during the HCTR. Effectiveness of HCTR: Within-group analysis: t, pVO2, 6-MWT increased significantly in TG: t 657±183 vs 766±181 (p<0.001), pVO2 19.2±5.0 vs 20.6±4.9 (p=0.007), 6-MWT 445±88 vs 551±77 (p<0.001). In the untrained CG, the unfavourable results were observed: 695±198 vs 717±187 (p=0.114), pVO2 21.2±5.1 vs 21.1±5.6 (p=0.723), 6-MWT 512±83 vs 536±84 (p=0.061). Between-group analysis: The differences between TG and CG were statistically significant: in Δt (p<0.001); ΔpVO2 (p=0.012); Δ6-MWT (p<0.001). Adherence to HCTR: In TG 28 patients (93%) completed the HCTR program. Two patients did no undergo HCTR because of personal issues. Conclusion Hybrid cardiac telerehabilitation in patients with HCM without the left ventricle (LV) outflow tract obstruction and preserved LV ejection fraction is safe and effective. The adherence to HCTR is high. Funding Acknowledgement Type of funding sources: Public Institution(s). Main funding source(s): Statutory work in The Cardinal Stefan Wyszyński National Institute of Cardiology in Warsaw, Poland

scholarly journals Contrast Enhanced Echocardiography-Controlled Alcohol Septal Ablation for Hypertrophic Cardiomyopathy with Left Ventricular Outflow Tract Obstruction

2019 ◽  
Vol 9 (2) ◽  
pp. 132-137
Author(s):  
I. E. Nikolaeva ◽  
V. V. Plechev ◽  
A. M. Mukhametyanov ◽  
R. M. Biktashev ◽  
I. V. Buzaev ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Left Ventricular Outflow Tract ◽  
Ventricular Outflow Tract ◽  
Left Ventricular ◽  
Outflow Tract ◽  
Alcohol Septal Ablation ◽  
Ventricular Outflow Tract Obstruction ◽  
Contrast Enhanced ◽  
Contrast Enhanced Echocardiography ◽  
Left Ventricular Outflow

In the SFHI (State Funded Healthcare Institution) Republic’s Centre for Cardiology the method of alcohol septal ablation has been introduced in 2015. The paper presents one case of a successful treatment of a patient with hypertrophic cardiomyopathy with left ventricular outflow tract obstruction treated with the use of the method of alcohol septal ablation under control of contrast enhanced echocardiography of the ablation area in the interventricular septum.

scholarly journals Haemodynamic Interplay Between Concomitant Left Ventricular Outflow Tract Obstruction and Aortic Stenosis

2021 ◽  
Vol 16 ◽  
Author(s):  
Priya Bansal ◽  
Hamza Lodhi ◽  
Adithya Mathews ◽  
Anand Desai ◽  
Ramez Morcos ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Aortic Stenosis ◽  
Left Ventricular Outflow Tract ◽  
Ventricular Outflow Tract ◽  
Left Ventricular ◽  
Outflow Tract ◽  
Alcohol Septal Ablation ◽  
Ventricular Outflow Tract Obstruction ◽  
Left Ventricular Outflow

The authors describe a patient with hypertrophic cardiomyopathy with concomitant left ventricular outflow tract obstruction and aortic stenosis. Detailed haemodynamic assessment of the serial lesions was performed. Alcohol septal ablation resulted in a significant reduction of gradients across the left ventricular outflow tract.

scholarly journals Pregnancy and severe left ventricle outflow tract obstruction in Hypertrophic Cardiomyopathy: a case report and review

2021 ◽  
Author(s):  
Ricardo Alves-Pinto ◽  
Tânia Proença ◽  
Miguel Martins-Carvalho ◽  
Paula Dias ◽  
Ana P. Machado ◽  
...  
Keyword(s):  
Case Report ◽  
Hypertrophic Cardiomyopathy ◽  
Left Ventricle ◽  
Outflow Tract

scholarly journals P1592 Papillary- annular continuum is a dynamic component of obstruction in outflow tract of left ventricle in patients with hypertrophic cardiomyopathy

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
E N Pavlyukova ◽  
A V Evtushenko ◽  
A F Kanev ◽  
R S Karpov
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Left Ventricle ◽  
Mitral Regurgitation ◽  
Outflow Tract ◽  
Papillary Muscles ◽  
Dynamic Component ◽  
Positive Strain ◽  
Apical Displacement ◽  
Peak Gradient

Abstract The aim to study was to assess Strain of papillary muscles (PM) and their apical displacement with 3D mitral valve (MV) parameters with maximal size of gradient of obstruction in the left ventricle outflow tract (LVOFT) and the volume of mitral regurgitation (MR) in hypertrophic cardiomyopathy (HCMP) patients. Material and methods. 72 HCMP patients (aged of 56.9 ± 11.1 years and gradient in LVOFT 70.83 ± 14.83 mm Hg at rest) were investigated. 3D TEE of MV was performed in all patients with follow up reconstruction. Strain of anterolateral (AL) and posteromedial (PM) papillary muscles (PM) was assess by TTE. Results Strain of both PM was decreased in 45 (62.5)% patients. Positive Strain PM PM were found in 20 (27.8%) patients and AL PM -in 7 (9.7%) patients. Apical displacement of PM PM were registered in 19 (38.0%) pts and ALPM in 6 (12.0%) pts. Apical displacement of both papillary muscles was found in 10 (20.0%) patients. Pts with positive Strain of PM PM had remodeling fibrous ring of MV as compared to patients who had negative Strain of this PM (anteroposterior diameter - 1.97 ± 0.23 sm/m² vs 1.63 ± 0.20sm/m²; p = 0, 01; the perimeter of the ring - 6.92 ± 0.69 sm/m2 vs 6.09 ± 0.93sm/m2; p = 0.02; the area of the ring (3D) - 6.91 ± 1.23sm²/m² vs 5,14 ± 1.31 sm²/m²; p = 0.005). These patients had large areas of the MV leaflets (anterior 4.83 ± 1.03 sm²/m² vs 3.19 ± 0.81 sm² /m² ; p = 0.007; posterior - 4.39 ± 0.42 sm²/m² vs 3.39 ± 1.18 sm²2/m²; p = 0.004), the area of the tenting of leaflets (2.98 ± 1.64 sm²/m² vs 1.24 ± 0.61 sm²/m²; p = 0.04) and the fraction of the tenting (69, 04 ± 24.9% vs 41.27 ± 17.59; p = 0.03). Patients with positive Strain had a greater volume of mitral regurgitation (24.20 ± 11.91 ml vs 14.04 ± 7.58 ml p = 0.004) and the peak gradient in LVOFT was 88.90 ± 37.90 mm Hg vs 66.35 ± 27.00 mm Hg; p = 0.02). Thus, the parameters of 3D MV and strain of PM represent a fixed papillary – annular continuum causing a dynamic component of the obstruction in the LV OT and the volume of mitral regurgitation in patients with HCMP.

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