scholarly journals Antimicrobial Properties and Melissopalynology, Proximate and Elemental Analyses of Honey Samples from Three Different Ecozones in Nigeria

2016 ◽  
Vol 8 (3) ◽  
pp. 326-333 ◽  
Author(s):  
Peter A. ADEONIPEKUN ◽  
Tiwalade A. ADENIYI ◽  
David EDEN
Keyword(s):  
Antimicrobial Properties ◽  
Pollen Grains ◽  
Antimicrobial Activities ◽  
Proximate Analysis ◽  
Preparation Methods ◽  
Antimicrobial Studies ◽  
Elemental Analyses ◽  
Lowland Rainforest ◽  
Sudan Savanna ◽  
First Time

Honey samples from three different ecozones - coastal freshwater (Ogba), lowland rainforest (Oka-Akoko) and montane Sudan savanna (Mambilla plateau) – were subjected to melissopalynological, proximate and elemental analyses, as well as antimicrobial studies. The aim of the research was to determine the contribution of pollen, if any, in the antimicrobial activities of the studied honey samples. Standard preparation methods were adopted for these studies. The Mambilla honey recorded the highest pollen diversity, while that of Oka-Akoko and Ogba regions had similar diversity, both having lower values. The Ogba honey however contained the highest abundance of pollen. Proximate analysis showed that the Mambilla honey also recorded the highest values of moisture, ash, protein, fats and oil, as well as potassium and reducing sugars. Antimicrobial investigation revealed the highest antimicrobial activities for the Mambilla honey, followed by Oka-Akoko and Ogba against Staphylococcus aureus (gram positive) and Pseudomonas aeruginosa (gram negative). Moisture content, proteins and carbohydrates were significantly different, with positive and negative trends respectively, when related with the antimicrobial activities of the honey samples. The pollen contents were also qualitatively different. This is the first time the antimicrobial activity of honey is ever traced to pollen contents.  More conclusions can be accurately made only after further research upon pollen grains directly.

scholarly journals Synthesis and Spectral Studies of Some Bioactive Transition Metal Complexes of [bis-2-(4-Fluorophenyl)prop-2-enaln]ethane-1,2-diamine

2019 ◽  
Vol 31 (10) ◽  
pp. 2357-2360
Author(s):  
Jagvir Singh ◽  
Anuradha ◽  
Pradeep Kumar ◽  
Mordhwaj ◽  
Ravi Kumar
Keyword(s):  
Staphylococcus Aureus ◽  
Metal Complexes ◽  
Antimicrobial Properties ◽  
Analysis Data ◽  
Antimicrobial Activities ◽  
Spectral Studies ◽  
Elemental Analysis Data ◽  
Chloride Complexes ◽  
Elemental Analyses ◽  
Uv Visible

Co(II), Ni(II) and Cu(II) metal complexes of a novel Schiff base ligand (SBL) derived from condensation of 2-(4-fluorophenyl)prop-2-enaln and ethane-1,2-diamine were synthesized. All the complexes were characterized by elemental analyses, IR, UV-visible spectroscopy, magnetic susceptibility and conductance measurements and 1H NMR. From the elemental analysis data, 1:1 [M]:[ligand] metal chloride complexes are formed having the general composition [M(SBL)Cl2] and [Cu(SBL)] Cl2, [where M = Co(II), Ni(II) and SBL= {bis-2-(4-fluorophenyl)prop-2-enaln}ethane-1,2-diamine]. The result showed that the ligand is coordinated to the metal ions in a neutral tetradentate manner with ON donor sites and the nature of metal-ligand bonding can range from covalent to ionic. Antimicrobial activities of the newly synthesized chemical compounds were evaluated against Staphylococcus aureus (ATCC 25923), Staphylococcus aureus (ATCC 3160), Cabdida albicans (ATCC 227) and Staphylococcus cereviscae (ATCC 361) species and found that metal complexes exhibited more antimicrobial properties so they are more potential and significant than the ligand.

scholarly journals Antimicrobial properties of terrestrial snail and slug mucus

2018 ◽  
Vol 15 (3) ◽  
Author(s):  
Giovanni Cilia ◽  
Filippo Fratini
Keyword(s):  
Antifungal Activity ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Future Application ◽  
Natural Antimicrobial ◽  
Future Studies ◽  
Antimicrobial Studies ◽  
Ancient Times ◽  
Natural Additives ◽  
Elastic Substance

Abstract Snail and slug mucus is a viscous-elastic substance secreted by specific glands with adhesive and lubricants properties that allows them to adhere tenaciously to many different surfaces. It has been used since ancient times for care and human health and it is still very important in traditional and folkloristic medicine. Recently, mucus from snail and slugs and its protein and components have been subjected to some investigations on their antibacterial, antiviral and antifungal activity due to extensive traditional uses and for a future application in medicine. Antimicrobial activities of crude mucus, and its components, against different microorganism have been reported, showing antimicrobial activities that lead their potential employment in several fields as natural additives. The purpose of this Review is to summarize the results of antimicrobial studies of snail and slug mucus and its compounds from the first scientific applications to the isolation of the single components in order to better understand its application and propose an employment in future studies as a natural antimicrobial agent.

scholarly journals Study on Europium-Doped Hydroxyapatite Nanoparticles by Fourier Transform Infrared Spectroscopy and Their Antimicrobial Properties

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Simona-Liliana Iconaru ◽  
Mikael Motelica-Heino ◽  
Daniela Predoi
Keyword(s):  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Fourier Transform Infrared Spectroscopy ◽  
Antimicrobial Properties ◽  
Fourier Transform Infrared ◽  
Nanocrystalline Powders ◽  
E Coli ◽  
Antimicrobial Studies ◽  
Ft Ir ◽  
First Time

Fourier transform infrared spectroscopy (FT-IR) analysis was conducted on europium-doped hydroxyapatite,Ca10-xEux(PO4)6(OH)2nanocrystalline powders (Eu:HAp) with0≤xEu≤0.2. Antimicrobial studies were also performed for the first time on Eu:HAp. The antimicrobial properties of Eu:HAp nanoparticles with0≤xEu≤0.2on Gram-negative (E. coli ATCC 25922,Pseudomonas aeruginosa 1397) and Gram-positive (Staphylococcus aureus 0364,Enterococcus faecalis ATCC 29212) bacteria systems and a species of fungus (Candida albicans ATCC 10231) were reported. Our study demonstrates that the antimicrobial activity of Eu:HAp nanoparticles is dependent on the europium concentration.

scholarly journals Synthesis, characterization and antimicrobial properties of two derivatives of pyrrolidine-2,5-dione fused at positions-3,4 to a dibenzobarrelene backbone

2021 ◽  
Author(s):  
Emmanuel Sopbué Fondjo ◽  
Abdou Salamou Njoya ◽  
Jean-de-Dieu Tamokou ◽  
Giscard Doungmo ◽  
Bruno Lenta Djakou ◽  
...  
Keyword(s):  
Antimicrobial Properties ◽  
Initial Step ◽  
Intermediate Compound ◽  
2D Nmr ◽  
Antimicrobial Activities ◽  
Fungal Species ◽  
Azo Compound ◽  
Biological Tests ◽  
First Time ◽  
Derivatives Of

Abstract Background : The present study describes for the first time, the synthesis of two pyrrolidine-2,5-dione derivatives that belong to N-arylsuccinimid (compound 5) and of azo (compound 8) class of molecules. The initial step of the reaction involved the preparation of the intermediate compound (9R, 10R, 11S)-9, 10-dihydro-9, 10-[3, 4] furanoanthracene-12, 14-dione (3) through [4 + 2]-cycloaddition between anthracene and maleic anhydride in xylene which was then condensed with para-hydroxyaniline to give compound 5. Subsequent coupling of 5 with the aryldiazonium ion of aniline gave compound 8.Results: These compounds were characterized by their physical, elemental, and spectroscopic data. 2D-NMR (COSY, HSQC, and HMBC) techniques were used to complete the elucidation of their structures. Compounds 5 (MIC = 32–128µg/mL) and 8 (MIC = 16–256µg/mL) along with the precursor 3 (MIC = 64–128µg/mL) displayed moderate antimicrobial activities against selected bacterial and fungal species when compared with those of nystatin (MIC = 0.50–2µg/mL) and ciprofloxacin (MIC = 0.50–16µg/mL) used as reference drugs.Conclusion: The results of biological tests showed that compounds 3, 5, 8 possess antimicrobial activities. Although being less active than the compound taken as a reference, the azo compound has better antibacterial activity than the other two compounds especially on Staphylococcus aureus, V. choleraeSG24 and, V. choleraeCO6 strains. These results show that the azo function (N = N) is indeed a pharmacophore and would be responsible for the biological activity in the azo molecules.

scholarly journals Synthesis of New Dicoumarol Based Zinc Compounds and their Invitro Antimicrobial Studies

2017 ◽  
Vol 59 (2) ◽  
Author(s):  
Sadia Rehman ◽  
Muhammad Ikram
Keyword(s):  
Spectroscopic Method ◽  
Erwinia Carotovora ◽  
Antimicrobial Activities ◽  
Mass Spectral Data ◽  
Zinc Compounds ◽  
Mass Spectral ◽  
Gram Positive Bacteria ◽  
Antimicrobial Studies ◽  
Elemental Analyses ◽  
Antimicrobial And Antifungal Activities

<p>The dicoumarol derivatives were reacted with Zn (II) salt yielding the complexes (<strong>1</strong>-<strong>10</strong>) where metal centre was seen to be coordinated with dicoumarols through hydroxyl and carbonyl sites of attachments. All the synthesized compounds were studied spectroscopically using 1H, 13C{1H}-NMR, infrared spectroscopic method, and analytically using ES(+,-)-MS, elemental analyses and conductance studies. The combined NMR and mass spectral data suggested the attachment of two ligands to the zinc (II) centre. Hydroxyl site is deprotonated and take part in charge neutralization of metal center. The synthesized zinc based dicoumarol compounds were screened for antimicrobial activities against Gram negative bacteria <em>Escherichia coli, Salmonella typhus</em>, <em>Agrobacterium tumefaciens</em>, <em>Erwinia carotovora, Pseudomonas aeruginosa</em>, <em>Klebsiella pneumoniae</em>, Gram positive bacteria <em>Staphylococcus aureus, Bacillus subtilis</em>, <em>Bacillus atrophaeus </em>and fungal Strain <em>Candida albicans</em>. All the compounds shown exceptional antimicrobial and antifungal activities.</p>

scholarly journals Antimicrobial Properties of the Ag, Cu Nanoparticle System

Biology ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 137
Author(s):  
Xinzhen Fan ◽  
L’Hocine Yahia ◽  
Edward Sacher
Keyword(s):  
Reactive Oxygen Species ◽  
Biomedical Application ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Oxygen Species ◽  
Cu Nanoparticles ◽  
Postoperative Infections ◽  
Nanoparticle System ◽  
Contact Killing ◽  
Bacteria And Fungi

Microbes, including bacteria and fungi, easily form stable biofilms on many surfaces. Such biofilms have high resistance to antibiotics, and cause nosocomial and postoperative infections. The antimicrobial and antiviral behaviors of Ag and Cu nanoparticles (NPs) are well known, and possible mechanisms for their actions, such as released ions, reactive oxygen species (ROS), contact killing, the immunostimulatory effect, and others have been proposed. Ag and Cu NPs, and their derivative NPs, have different antimicrobial capacities and cytotoxicities. Factors, such as size, shape and surface treatment, influence their antimicrobial activities. The biomedical application of antimicrobial Ag and Cu NPs involves coating onto substrates, including textiles, polymers, ceramics, and metals. Because Ag and Cu are immiscible, synthetic AgCu nanoalloys have different microstructures, which impact their antimicrobial effects. When mixed, the combination of Ag and Cu NPs act synergistically, offering substantially enhanced antimicrobial behavior. However, when alloyed in Ag–Cu NPs, the antimicrobial behavior is even more enhanced. The reason for this enhancement is unclear. Here, we discuss these results and the possible behavior mechanisms that underlie them.

scholarly journals Antimicrobial and Immunomodulating Activities of Two Endemic Nepeta Species and Their Major Iridoids Isolated from Natural Sources

2021 ◽  
Vol 14 (5) ◽  
pp. 414
Author(s):  
Neda Aničić ◽  
Uroš Gašić ◽  
Feng Lu ◽  
Ana Ćirić ◽  
Marija Ivanov ◽  
...  
Keyword(s):  
Biofilm Formation ◽  
Food Industry ◽  
Balkan Peninsula ◽  
Antimicrobial Activities ◽  
Natural Sources ◽  
E Coli ◽  
Food Borne ◽  
Metabolite Profiles ◽  
Aspergillus Sp ◽  
First Time

Two Balkan Peninsula endemics, Nepeta rtanjensis and N. argolica subsp. argolica, both characterized by specialized metabolite profiles predominated by iridoids and phenolics, are differentiated according to the stereochemistry of major iridoid aglycone nepetalactone (NL). For the first time, the present study provides a comparative analysis of antimicrobial and immunomodulating activities of the two Nepeta species and their major iridoids isolated from natural sources—cis,trans-NL, trans,cis-NL, and 1,5,9-epideoxyloganic acid (1,5,9-eDLA), as well as of phenolic acid rosmarinic acid (RA). Methanol extracts and pure iridoids displayed excellent antimicrobial activity against eight strains of bacteria and seven strains of fungi. They were especially potent against food-borne pathogens such as L. monocytogenes, E. coli, S. aureus, Penicillium sp., and Aspergillus sp. Targeted iridoids were efficient agents in preventing biofilm formation of resistant P. aeruginosa strain, and they displayed additive antimicrobial interaction. Iridoids are, to a great extent, responsible for the prominent antimicrobial activities of the two Nepeta species, although are probably minor contributors to the moderate immunomodulatory effects. The analyzed iridoids and RA, individually or in mixtures, have the potential to be used in the pharmaceutical industry as potent antimicrobials, and in the food industry to increase the shelf life and safety of food products.

scholarly journals New Synthetic Methods of Novel Nanoporous Polycondensates and Excellent Oxygen Permselectivity of Their Composite Membranes

Nanomaterials ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 859
Author(s):  
Yu Zang ◽  
Toshiki Aoki ◽  
Masahiro Teraguchi ◽  
Takashi Kaneko ◽  
Hongge Jia ◽  
...  
Keyword(s):  
Contact Angle ◽  
Upper Bound ◽  
Oxygen Permeability ◽  
Membrane Surface ◽  
Composite Membranes ◽  
Synthetic Methods ◽  
Preparation Methods ◽  
First Time

Two kinds of novel nanoporous polycondensates (sc(Rf)) have been synthesized by two new preparation methods consisting of polycondensation and highly selective photocyclicaromataization of 1/3 helical cis-cis polyphenylacetylenes with polymerizable groups. By the original methods, new well-defined sheet polymers having nanopores or nanospaces have been synthesized for the first time. Their composite membranes, containing small amounts (1.0 wt%) of sc(Rf), had ultrahigh oxygen permeability (Po2 > 1000 barrer), and their plots were beyond the Robeson’s upper bound line in the graph of oxygen permselectivity (α = Po2/PN2) versus Po2. Both α and Po2 values were enhanced by adding only small amounts (1.0 wt%) of sc(Rf). One of the sc(Rf)s synthesized on the base membrane surface showed the best performance, i.e., Po2 = 5300 barrer and α = 2.5. The membrane surface was effectively covered by sc(Rf), judging from the contact angle values. It is thought that nanopores and nanospaces created in and between sc(Rf) molecules played an important role for the enhancement of both α and Po2/PN2.

scholarly journals In VitroAntimicrobial Activity of Extracts from Plants Used Traditionally in South Africa to Treat Tuberculosis and Related Symptoms

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Balungile Madikizela ◽  
Ashwell Rungano Ndhlala ◽  
Jeffrey Franklin Finnie ◽  
Johannes Van Staden
Keyword(s):  
South Africa ◽  
South African ◽  
Respiratory Infections ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Phytochemical Analysis ◽  
Traditional Use ◽  
Microbial Strains ◽  
African Plants ◽  
Mycobacterium Aurum

Respiratory ailments are major human killers, especially in developing countries. Tuberculosis (TB) is an infectious disease causing a threat to human healthcare. Many South African plants are used in the traditional treatment of TB and related symptoms, but there has not been a sufficient focus on evaluating their antimicrobial properties. The aim of this study was to evaluate the antimicrobial properties of plants used traditionally to treat TB and related symptoms against microorganisms (Klebsiella pneumoniae, Staphylococcus aureus,andMycobacterium aurumA+) associated with respiratory infections using the microdilution assay. Ten plants were selected based on a survey of available literature of medicinal plants used in South Africa for the treatment of TB and related symptoms. The petroleum ether, dichloromethane, 80% ethanol, and water extracts of the selected plants were evaluated for antibacterial activity. Out of 68 extracts tested from different parts of the 10 plant species, 17 showed good antimicrobial activities against at least one or more of the microbial strains tested, with minimum inhibitory concentration ranging from 0.195 to 12.5 mg/mL. The good antimicrobial properties ofAbrus precatorius, Terminalia phanerophlebia, Indigofera arrecta,andPentanisia prunelloidesauthenticate their traditional use in the treatment of respiratory diseases. Thus, further pharmacological and phytochemical analysis is required.

scholarly journals Antimicrobial Activities in Pistacia atlantica—Aphids Make a Difference!

Proceedings ◽  
2020 ◽  
Vol 66 (1) ◽  
pp. 9
Author(s):  
Yoram Gerchman
Keyword(s):  
Secondary Metabolites ◽  
Essential Oils ◽  
Organic Solvents ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Disk Diffusion ◽  
Pistacia Atlantica ◽  
Disk Diffusion Assay ◽  
Bacteria And Fungi ◽  
Diffusion Assay

Plants have been explored and used as sources for antimicrobial extract and compounds for many years, but galls—specialized structures forms on such by diversity of organisms—have been explored much less. Aphid galls host many insects in closed, humid and sugar rich environments for long periods. We have tested the antimicrobial properties of Slavum wertheimae aphid galls on Pistacia atlantica. Secondary metabolites were extracted from leaves and galls with organic solvents, and essential oils with Clevenger, and tested by disk diffusion assay and volatile effect on bacteria and fungi, respectively. The results demonstrated that gall extracts/essential oils had much stronger activity against the diversity of bacteria and fungi. The large diversity of galls suggest they could be explored as source for novel compounds.

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