scholarly journals Introduction Pages

2019 ◽  
Vol 11 (3) ◽  
pp. I-VIII
Author(s):  
Radu E. SESTRAS
Keyword(s):  
Conservation Status ◽  
Photosynthetic Pigment ◽  
Clinical Signs ◽  
Ethanolic Extract ◽  
Carbapenem Resistance ◽  
Zingiber Officinale ◽  
Serum Biochemistry ◽  
Clinicopathological Findings ◽  
Western Ghats Of India

Notulae Scientia Biologicae (http://www.notulaebiologicae.ro), Issue 3, Volume 11, 2019: The papers published in this issue (https://www.notulaebiologicae.ro/index.php/nsb/issue/view/265) represent interesting novelties in different topics of life science. Among the exciting researches, we invite readers to find news about: pharmacological uses and health benefits of ginger (Zingiber officinale) in traditional Asian and ancient Chinese medicine, and modern practice; middle east respiratory syndrome: its occurrence, aetiology, epidemiology, associated clinicopathological findings, diagnosis, prevention and control in humans and animals; ethanolic extract of Chrysophyllum albidum stem bark prevents alloxan-induced diabetes; prevalence of group a rotavirus, some risk factors and clinical signs of the infection in children under five years in Yobe State, Nigeria; prevalence of increased serum urea and creatinine levels in dogs; impact of heat stress on blood and serum biochemistry parameters in rats; acute and sub-acute toxicity of Ganoderma applanatum (Pres.) Pat. extract mediated silver nanoparticles on rat; in-vitro control of oral thrush causal organisms using medicinal plants extracts; generic salmonella in asymptomatic adult volunteers: occurrence, antibiogram, extended-spectrum β-lactamase production and carbapenem resistance; impact of hydrogen peroxide on the secondary metabolites, enzyme activities and photosynthetic pigment accumulation of Vigna unguiculata L. (Walp); diversity, distribution and conservation status of the genus Tectaria Cav. from Deccan Peninsula and western Ghats of India.

scholarly journals Immunostimulant Effect of Egyptian Propolis in Rabbits

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Somya A. Nassar ◽  
Amira H. Mohamed ◽  
Hamdy Soufy ◽  
Soad M. Nasr ◽  
K. M. Mahran
Keyword(s):  
Immune Response ◽  
Pasteurella Multocida ◽  
Histopathological Examination ◽  
Virulent Strain ◽  
Clinical Signs ◽  
Ethanolic Extract ◽  
Serum Biochemistry ◽  
Alcoholic Extract ◽  
Propolis Extract ◽  
Tissue Specimens

The present experiment was conducted to study the effect of ethanolic extract of Egyptian propolis given alone or in combination with inactivatedPasteurella multocidavaccine on rabbits challenged with a virulent strain ofPasteurella multocida. Fifty-six New-Zealand rabbits, 6–8 weeks old and non-vaccinated against pasteurellosis, were randomly divided into eight equal groups. The first group was kept as a control for the experiment. The other groups received different treatments with propolis extract, inactivated vaccine, or both. The experiment continued for seven weeks during which clinical signs, body weight, and mortality rate were monitored, and blood samples were collected weekly for evaluating the leukogram, serum biochemistry, and immune response in all groups of animals. At the end of the seventh week, the animals were subjected to challenge with a virulent strain ofPasteurella multocida. Two weeks later, tissue specimens were collected from different organs for histopathological examination. Results showed that rabbits of the groups treated with both propolis and the vaccine by different routes appeared healthy after challenge. It has been concluded that alcoholic extract of propolis administrated in combination with inactivatedPasteurella multocidavaccine has no adverse effects on the general health conditions and enhances immune response in rabbits.

In-vitro study of the efficacy of ethanolic extract of Zingiber officinale on biofilm formed by pharyngeal isolate

2019 ◽  
pp. 320-324
Author(s):  
Dibyajit Lahiri ◽  
Moupriya Nag ◽  
Bandita Dutta ◽  
Indranil Mukherjee ◽  
Shreyasi Ghosh ◽  
...  
Keyword(s):  
In Vitro Study ◽  
Ethanolic Extract ◽  
Zingiber Officinale ◽  
Vitro Study

scholarly journals In Vitro Antioxidant Activity of Zingiber officinale, Piper retrofractum, and Their Combinations

2011 ◽  
Vol 2 (3) ◽  
pp. 295 ◽  
Author(s):  
Hendri Wasito ◽  
Heny Ekowati ◽  
Fitri Fauziah Hayati
Keyword(s):  
Antioxidant Activity ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Zingiber Officinale ◽  
Free Radical Scavenging ◽  
Dpph Method ◽  
Piper Retrofractum ◽  
X 24 ◽  
In Vitro Antioxidant Activity

Many plants are used empirically as antioxidant. Plants that are frequently used in Indonesian communities are Zingiber officinale and Piper retrofractum. The aim of this research was to investigate the in vitro antioxidant activity of single ethanolic extract and the combinations ofZ. officinale and P. retrofratum using free radical scavenging DPPH (1,1-diphenyl-2-picrylhydrazyl) method. Z. officinale and P. retrofratum were extracted by maceration using 95% ethanol for 3 x 24 hours. Antioxidant activity was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. The concentration of the extract (μg/mL) that was required to scavenge 50% of free radicals (IC50)was calculatedusing the percent scavenging activities of six different extract concentrations. The results showed that the single ethanolic extract of Z. Officinalle produced the highest antioxidant activity with IC50of 56 μg/mL, while the antioxidant  activity of the single ethanolic extract of  P. retrofractum produced an IC50 of 3.445 μg/mL. The IC50 of combination of Z. officinale and P. retrofratum ethanolic extracts at concentration ratios of 1: 2, 1 : 1, and 2 : 1 were 148 μg/mL, 85 μg/mL, and 73 μg/mL.Keywords: Zingiber officinale, Piper retrfratum, Antioxidant, DPPH

scholarly journals Evaluation of Subchronic Toxicity and Genotoxicity of Ethanolic Extract of Aster glehni Leaves and Stems

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Mi Kyung Lim ◽  
Ju Yeon Kim ◽  
Jeongho Jeong ◽  
Eun Hye Han ◽  
Sang Ho Lee ◽  
...  
Keyword(s):  
Micronucleus Test ◽  
Clinical Signs ◽  
Ethanolic Extract ◽  
Clinical Work ◽  
Negative Results ◽  
Animal Toxicity ◽  
The Republic ◽  
Chromosomal Aberration Test

Aster glehni, a traditional plant on Ulleung Island in the Republic of Korea, has been recognized for its multiple medicinal properties. However, potential toxicity and safety analyses of A. glehni have not been previously investigated. Therefore, this study aimed to evaluate the safety profile of ethanolic extract of A. glehni leaves and stems (EAG) in terms of genotoxicity and subchronic oral animal toxicity under OECD guidelines and GLP conditions. Toxicological assessments were performed at doses of 1,250, 2,500, and 5,000 mg/kg/day in a 13-week oral repeated-dose toxicity study of EAG in male and female SD rats. In addition, an Ames test, an in vitro mammalian chromosomal aberration test, and a micronucleus test were performed. No toxicological changes in clinical signs, body weights, water and food consumption, urinalysis, hematology, clinical biochemistry, gross findings, and histopathological examinations were observed in subchronic oral animal toxicity. In addition, EAG gave negative results when evaluated using in vitro and in vivo genotoxicity tests. In conclusion, the no-observed-adverse-effect level (NOAEL) of EAG was considered to be 5,000 mg/kg/day, and no target organs were identified in both sexes of rats. EAG was also classified as nonmutagenic and nonclastogenic in genotoxicity testing. Collectively, these results show a lack of general toxicity and genotoxicity for EAG that supports clinical work for development as a herbal medicine.

Potentiation of doxorubicin (DXR)'s genotoxic activities by ethanolic extract from Thai Plumbago indica roots (EEPIR) in human lymphocytes in vitro

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
T Ratanavalachai ◽  
S Thitiorul ◽  
S Tanuchit ◽  
A Itharat ◽  
I Sakpakdeejaroen
Keyword(s):  
Human Lymphocytes ◽  
Ethanolic Extract ◽  
Plumbago Indica

Protective effects of Dioscorea membranacea rhizome ethanolic extract against doxorubicin-induced genotoxicity in human lymphocytes in vitro

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
T Ratanavalachai ◽  
S Thitiorul ◽  
A Itharat ◽  
N Runraksa ◽  
S Ruangnoo
Keyword(s):  
Human Lymphocytes ◽  
Ethanolic Extract ◽  
Protective Effects

Dwindling status of Epimedium Elatum (Morren & Decne) and its geographical distribution in Kashmir Himalaya, India

2018 ◽  
pp. 47-52
Keyword(s):  
Medicinal Plant ◽  
Biological Activities ◽  
Conservation Status ◽  
Natural Populations ◽  
Culture Techniques ◽  
Kashmir Himalayas ◽  
Near Future ◽  
First Time ◽  
Tissue Culture Techniques

Epimedium elatum (Morren & Decne) of family Berberidaceace is a rare perennial medicinal plant, endemic to high altitude forests of Northwestern Himalayas in India. Ethnobotanically, it has been used as an ingredient for treatment of bone-joint disorders, impotence and kidney disorders in Kashmir Himalayas. Phytochemically, it is rich in Epimedin ABC and Icariin; all of these have been demonstrated to possess remarkable biological activities like PDE-5 inhibition (treatment of erectile dysfunction), anticancer, antiosteoporosis antioxidant and antiviral properties. The present investigation reports its traditional usage, comprehensive distribution and conservation status from twenty ecogeographical regions in Kashmir Himalayas, India. The species was reported from Gurez valley for the first time. Numerous threats like excessive grazing, deforestration, habitat fragmentation, tourism encroachment, landslides and excessive exploitation have decreased its natural populations in most of the surveyed habitats. Consequently, its existence may become threatened in near future if timely conservation steps are not taken immediately by concerned stakeholders involved in medicinal plant research. Moreover, use of plant tissue culture techniques is recommended for development of its in vitro propagation protocols. Therefore, introduction of this medicinal plant in botanical gardens, protected sites and development of monitoring programmes are needed for its immediate conservation in Northwestern Himalayas, India.

A comparative study of the antibacterial activity of Quercus robur (Ethanolic extract) and Zinc oxide nanoparticles on Salmonella (In vitro)

2018 ◽  
Vol 9 (SPL1) ◽  
Author(s):  
Hams H. H. Alfattli ◽  
Ghufran Zuhair Jiber ◽  
Ghaidaa Gatea Abbass
Keyword(s):  
Zinc Oxide ◽  
Antibacterial Activity ◽  
Zinc Oxide Nanoparticles ◽  
Quercus Robur ◽  
Ethanolic Extract ◽  
Inhibitory Effect ◽  
Significant Inhibition ◽  
Oxide Nanoparticles ◽  
Inhibition Zones

This study which designed to evaluate the inhibitory effect of Ethanolic extract of (Quercusrobur) and Zinc oxide nanoparticles on the growth of one genus of enterobacteriacae (Salmonella). In vitro. For this purpose graduate concentrates for plant extract (50, 100, 200, 400 )mg/ml which prepared and compared with Zinc oxide nanoparticles of different concentration (2, 1, 0.5, 0.25) μg/ml,and examined. The result showed that the studied medicinal plant has antibacterial activity against this bacteria which used. The result showed that the plant has good activity in decrease the growth of this bacteria. The results of the study also showed that the nano-ZnO has very effective antibacterial action against the studied bacteria which was Salmonella,nanoparticles concentrations lead to increasing in the inhibition zones of tested bacterial growth. We also study the effect of three antibiotics Lomefloxacin (LOM), Ciprofloxacin (SIP) and Rifampin (RA) and the result showed,in a comparison within the tested bacteria,Salmonella had a significant inhibition increase in Lomefloxacin ; the ciprofloxacin showed effect on tested bacteria. However,Rifampin does not show any effect on tested bacteria.

AVALIAÇÃO IN VITRO DO EXTRATO HIDROALCOÓLICO E AQUOSO DE GENGIBRE (Zingiber officinale [WILLD.] ROSCOE) SOBRE O FUNGO Lasiodiplodia theobromae

2018 ◽  
pp. 80
Author(s):  
Lavinia dos Santos Mascarenhas ◽  
Monica Junqueira Machado ◽  
Noelma de Brito Miranda ◽  
Vânia de Jesus Santos Oliveira ◽  
Pedro Henrique Ribeiro Santana
Keyword(s):  
Zingiber Officinale ◽  
Lasiodiplodia Theobromae
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