Processing Nigerian pyrolusite ore, Part I: Characterization and dissolution kinetics analysis

CIM Journal ◽  
2016 ◽  
Vol 7 (1) ◽  
pp. 43-51 ◽  
Author(s):  
A. A. Baba ◽  
L. Ibrahim ◽  
R. B. Bale ◽  
A. G. F. Alabi ◽  
F. A. Adekola ◽  
...  
Keyword(s):  
Dissolution Kinetics ◽  
Kinetics Analysis

Dissolution Kinetics Analysis for Chemically Amplified Deep Ultraviolet Resist

1994 ◽  
Vol 33 (Part 1, No. 12B) ◽  
pp. 7005-7011 ◽  
Author(s):  
Toshiro Itani ◽  
Haruo Iwasaki ◽  
Masashi Fujimoto ◽  
Kunihiko Kasama
Keyword(s):  
Dissolution Kinetics ◽  
Kinetics Analysis ◽  
Chemically Amplified ◽  
Deep Ultraviolet

Kinetics Analysis of Reaction between Molybdenum and Nitrogen Trifluoride

2021 ◽  
Vol 49 (4) ◽  
pp. e21039-e21045
Author(s):  
Yong-Sheng NIU ◽  
Li-Xin SUN ◽  
Cong-Wei HU ◽  
Jin-Hao ZHOU ◽  
Qiang DOU ◽  
...  
Keyword(s):  
Kinetics Analysis ◽  
Nitrogen Trifluoride

scholarly journals Study of deposition parameters and growth kinetics of ZnO deposited by aerosol assisted chemical vapor deposition

RSC Advances ◽  
2021 ◽  
Vol 11 (30) ◽  
pp. 18493-18499
Author(s):  
Sergio Sánchez-Martín ◽  
S. M. Olaizola ◽  
E. Castaño ◽  
E. Urionabarrenetxea ◽  
G. G. Mandayo ◽  
...  
Keyword(s):  
Chemical Vapor Deposition ◽  
Growth Kinetics ◽  
Vapor Deposition ◽  
Chemical Vapor ◽  
Kinetics Analysis ◽  
Deposition Parameters ◽  
Kinetics Of

Impact of deposition parameters, microstructure and growth kinetics analysis of ZnO grown by Aerosol-assisted Chemical Vapor Deposition (AACVD).

scholarly journals Kinetic Constraints in the Specific Interaction between Phosphorylated Ubiquitin and Proteasomal Shuttle Factors

Biomolecules ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1008
Author(s):  
Ling-Yun Qin ◽  
Zhou Gong ◽  
Kan Liu ◽  
Xu Dong ◽  
Chun Tang
Keyword(s):  
Exchange Rate ◽  
Self Assembly ◽  
Solution Structure ◽  
Specific Interaction ◽  
Dissociation Rate ◽  
Fine Tuning ◽  
Binding Mechanism ◽  
Kinetics Analysis ◽  
Kinetic Constraint ◽  
Thermodynamic Basis

Ubiquitin (Ub) specifically interacts with the Ub-associating domain (UBA) in a proteasomal shuttle factor, while the latter is involved in either proteasomal targeting or self-assembly coacervation. PINK1 phosphorylates Ub at S65 and makes Ub alternate between C-terminally relaxed (pUbRL) and retracted conformations (pUbRT). Using NMR spectroscopy, we show that pUbRL but not pUbRT preferentially interacts with the UBA from two proteasomal shuttle factors Ubqln2 and Rad23A. Yet discriminatorily, Ubqln2-UBA binds to pUb more tightly than Rad23A does and selectively enriches pUbRL upon complex formation. Further, we determine the solution structure of the complex between Ubqln2-UBA and pUbRL and uncover the thermodynamic basis for the stronger interaction. NMR kinetics analysis at different timescales further suggests an indued-fit binding mechanism for pUb-UBA interaction. Notably, at a relatively low saturation level, the dissociation rate of the UBA-pUbRL complex is comparable with the exchange rate between pUbRL and pUbRT. Thus, a kinetic constraint would dictate the interaction between Ub and UBA, thus fine-tuning the functional state of the proteasomal shuttle factors.

scholarly journals Identifying Critical Binder Attributes to Facilitate Binder Selection for Efficient Formulation Development in a Continuous Twin Screw Wet Granulation Process

Pharmaceutics ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 210
Author(s):  
Lise Vandevivere ◽  
Maxine Vangampelaere ◽  
Christoph Portier ◽  
Cedrine de Backere ◽  
Olaf Häusler ◽  
...  
Keyword(s):  
Dissolution Kinetics ◽  
Wet Granulation ◽  
Continuous Manufacturing ◽  
Formulation Development ◽  
Granulation Process ◽  
Low Viscosity ◽  
Twin Screw ◽  
Poorly Soluble ◽  
Selection For ◽  
The Impact

The suitability of pharmaceutical binders for continuous twin-screw wet granulation was investigated as the pharmaceutical industry is undergoing a switch from batch to continuous manufacturing. Binder selection for twin-screw wet granulation should rely on a scientific approach to enable efficient formulation development. Therefore, the current study identified binder attributes affecting the binder effectiveness in a wet granulation process of a highly soluble model excipient (mannitol). For this formulation, higher binder effectiveness was linked to fast activation of the binder properties (i.e., fast binder dissolution kinetics combined with low viscosity attributes and good wetting properties by the binder). As the impact of binder attributes on the granulation process of a poorly soluble formulation (dicalcium phosphate) was previously investigated, this enabled a comprehensive comparison between both formulations in current research focusing on binder selection. This comparison revealed that binder attributes that are important to guide binder selection differ in function of the solubility of the formulation. The identification of critical binder attributes in the current study enables rational and efficient binder selection for twin-screw granulation of well soluble and poorly soluble formulations. Binder addition proved especially valuable for a poorly soluble formulation.

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