scholarly journals Hemorrhage under antivitamins K: a location like no other

2017 ◽  
Vol 3 (10) ◽  
Author(s):  
Amine Salmi
Keyword(s):  
Antivitamins K

New anticoagulants in clinical practice. Effectiveness and problems

2016 ◽  
Vol 94 (5) ◽  
pp. 383-387
Author(s):  
Igor N. Bokarev ◽  
T. B. Kondrat’eva
Keyword(s):  
Atrial Fibrillation ◽  
Acute Coronary Syndrome ◽  
Clinical Practice ◽  
Oral Anticoagulants ◽  
New Oral Anticoagulants ◽  
Coronary Syndrome ◽  
New Anticoagulants ◽  
Antivitamins K

We analyze the effectiveness of new oral anticoagulants and antivitamins K for the treatment of patients with venous problems, atrial fibrillation, and acute coronary syndrome with reference to advantages of this therapy and methods of prevention of complications of these conditions.

Anticoagulants today

2016 ◽  
Vol 94 (1) ◽  
pp. 5-9
Author(s):  
Igor N. Bokarev
Keyword(s):  
Clinical Application ◽  
Oral Anticoagulants ◽  
Antivitamins K

A review of modern concepts of clinical application of anti-thrombotic drugs, such as heparins, antivitamins K, oral anticoagulants, and thrombolytics is presented.

Vitamins and antivitamins K: tautomerism of dicoumarol

Tetrahedron ◽  
1958 ◽  
Vol 4 (1-2) ◽  
pp. 135-146 ◽  
Author(s):  
I. Chmielewska ◽  
J. Cieślak
Keyword(s):  
Antivitamins K

scholarly journals 0526: Predictive factors for obtaining a correct therapeutic range using antivitamins K: a tertiary center experience

2015 ◽  
Vol 7 (1) ◽  
pp. 90
Author(s):  
Ruxandra Jurcut ◽  
Ciprian Jurcut ◽  
Sebastian Militaru ◽  
Oliviana Geavlete ◽  
Nic Dragotoi ◽  
...  
Keyword(s):  
Predictive Factors ◽  
Therapeutic Range ◽  
Tertiary Center ◽  
Antivitamins K

scholarly journals Haemorrhagic Accidents Linked to Antivitamins K in Emergencies

2021 ◽  
Vol 05 (01) ◽  
pp. 91-100
Author(s):  
Raihane BAHRI ◽  
Fadoua ELFARSSANI ◽  
Siham KHAYATI ◽  
Saida EDDYB ◽  
Hicham YAHYAOUI ◽  
...  
Keyword(s):  
Antivitamins K

A stereodynamic investigation of antivitamins K in the dicoumarol series. II. Differentiation between the two hydroxyl groups by the nuclear Overhauser effect

1976 ◽  
Vol 54 (5) ◽  
pp. 813-816 ◽  
Author(s):  
Claude Laruelle ◽  
Jean-Jacques Godfroid
Keyword(s):  
Chemical Exchange ◽  
Nuclear Overhauser Effect ◽  
Hydroxyl Groups ◽  
Hindered Rotation ◽  
Interatomic Distances ◽  
Overhauser Effect ◽  
Nuclear Overhauser ◽  
A Site ◽  
Hydroxyl Protons ◽  
Antivitamins K

Dicoumarol derivatives, substituted at the bridgehead, show a double restricted rotation. This hindered rotation is manifest through the appearance of two signals, the hydroxyl protons being diastereotopic at low temperatures.In this work we assign the two respective signals by the nuclear Overhauser effect. The high-field signal corresponds to a hydroxyl site close to the bridgehead tertiary proton, while the other corresponds to a site in proximity to the substituent R. The case of structurally analogous dimethones has been investigated by the same technique with identical conclusions. This disproves the interpretation made previously on the basis of steric and anisotropic effects.The interatomic distances concerned have been calculated, and these have yielded an estimate of deformations induced by the bridgehead substituents.Evidence is supplied for the different behavior of the two sites and this study gives evidence for a very facile intermolecular chemical exchange of the hydroxyl site close to the tertiary bridgehead proton in the presence of traces of protonated compounds.The overall behavior is the result of the asymmetry of the molecules of this series in their chelated form.

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