Comparison of Respiratory Morbidity in Late Preterm and Term Infants at a Single Institution

2014 ◽  
Vol 18 (2) ◽  
pp. 85-90
Author(s):  
Won Hee Choi ◽  
Eun-Kyeong Yeon ◽  
Young-Lim Shin ◽  
Won Suk Suh ◽  
Jang Yong Jin
Keyword(s):  
Late Preterm ◽  
Respiratory Morbidity ◽  
Single Institution ◽  
Term Infants

A randomized controlled trial of restricted versus standard fluid management in late preterm and term infants with transient tachypnea of the newborn

2020 ◽  
Vol 13 (4) ◽  
pp. 477-487
Author(s):  
S. Sardar ◽  
S. Pal ◽  
R. Mishra
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Initial Period ◽  
Fluid Management ◽  
Late Preterm ◽  
Respiratory Morbidity ◽  
Term Infants ◽  
Randomized Controlled ◽  
Antenatal Steroid ◽  
Preterm Babies

BACKGROUND: Transient tachypnea of the newborn(TTNB) is the most common respiratory morbidity in late preterm and term babies and is pathophysiologically related to delayed lung fluid clearance after birth. Mimicking low physiological fluid intake in the initial period of life may accelerate the recovery from TTNB. In a randomized controlled trial, we compared the roles of restricted versus standard fluid management in babies with TTNB requiring respiratory support. METHODS: This parallel group,non-blinded, stratified randomized controlled trial was conducted in a level III neonatal unit of eastern India. Late preterm and term babies with TTNB requiring continuous positive airway pressure (CPAP) were randomly allocated to standard and restricted fluid arms for the first 72 hours (hrs). Primary outcome was CPAP duration. RESULTS: In total, 100 babies were enrolled in this study with 50 babies in each arm. CPAP duration was significantly less in the restricted arm (48[42, 54] hrs vs 54[48,72] hrs, p = 0.002). However, no difference was observed in the incidence of CPAP failure between the two arms. In the subgroup analysis, the benefit of reduced CPAP duration persisted in late preterm but not in term infants. However, the effect was not significant in the late preterm babies exposed to antenatal steroid. CONCLUSION: This trial demonstrated the safety and effectiveness of restrictive fluid strategy in reducing CPAP duration in late preterm and term babies with TTNB. Late preterm babies, especially those not exposed to antenatal steroid were the most benefitted by this strategy.

scholarly journals Early health issues in late pre-terms

2019 ◽  
Vol 6 (2) ◽  
pp. 369
Author(s):  
Monica Choudhary ◽  
Kamna Jain
Keyword(s):  
Preterm Infants ◽  
Preterm Births ◽  
Late Preterm ◽  
Morbidity And Mortality ◽  
Respiratory Morbidity ◽  
Preterm Neonates ◽  
Term Infants ◽  
Term Neonates ◽  
Late Preterm Infants ◽  
Early Health

Background: Rates of preterm birth are increasing worldwide, mostly due to late preterm births (i.e. 34-36 6/7 weeks). The objective of the study is to calculate incidence of early morbidity and mortality in late preterm neonates (within first 7 days of life) compared with term neonates.Methods: It was a prospective cohort study. All live inborn late preterm infants (34 0/7 to 36 6/7 weeks) and term infants (37 0/7 to 41 6/7 weeks) who were born between November 2010 to October 2011. Study was done to find out early morbidity and mortality in late preterm births.Results: Present study included 256 late preterm infants and 498 term infants, amongst whom 95 (37.10%) late preterm and 98 (19.67%) term infants required NICU care (p<0.001). Late preterm infants were at significantly higher risk for overall morbidity due to any cause (P<0.001; Odds Ratio (OR):2.4; 95% CI: 1.7-3.3), respiratory morbidity (P<0.001; OR:3.64; 95% CI:1.7-7.4), neonatal depression (p<0.001; OR:2.94; 95% CI:1.00-8.62), any resuscitation/ventilation (P<0.05; OR: 3.1; 95% CI:1.15-8.31), probable sepsis (P<0.001; OR:11.2; 95% CI:2.5-49.8), confirmed sepsis (p=0.05; OR:7.7; 95% CI:0.9-63.9), or other problems like jaundice, hypoglycemia, hypothermia and feeding difficulty. The incidence of morbidity increased as gestational age decreases from 19.67% in term infants (>37 weeks) to 27.8%, 43%, 54.5% at 36, 35 and 34 weeks, respectively (P<0.001).Conclusions: The morbidity risk in late preterm births is 1.3 times more at 36 weeks, 2 times more at 35 weeks and 2.7 times more at 34 weeks as compared with term neonates. The mean cost of stay increased 1.8 times in the late preterm neonates as compared to the term neonates.

Neonatal respiratory morbidity following elective caesarean section in term infants

2001 ◽  
Vol 98 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Anemone van den Berg ◽  
Ruurd M van Elburg ◽  
Herman P van Geijn ◽  
Willem P.F Fetter
Keyword(s):  
Caesarean Section ◽  
Elective Caesarean Section ◽  
Respiratory Morbidity ◽  
Term Infants

scholarly journals Trends in Costs of Birth Hospitalization and Readmissions for Late Preterm Infants

Children ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 127
Author(s):  
Rebecca R. Speer ◽  
Eric W. Schaefer ◽  
Mahoussi Aholoukpe ◽  
Douglas L. Leslie ◽  
Chintan K. Gandhi
Keyword(s):  
Preterm Infants ◽  
Private Insurance ◽  
The United States ◽  
Late Preterm ◽  
Term Infants ◽  
Late Preterm Infants ◽  
Hospitalization Costs ◽  
Analysis Of Claims Data ◽  
Mean Cost ◽  
Birth Hospitalization

Background: The objective is to study previously unexplored trends of birth hospitalization and readmission costs for late preterm infants (LPIs) in the United States between 2005 and 2016. Methods: We conducted a retrospective analysis of claims data to study healthcare costs of birth hospitalization and readmissions for LPIs compared to term infants (TIs) using a large private insurance database. We used a generalized linear regression model to study birth hospitalization and readmission costs. Results: A total of 2,123,143 infants were examined (93.2% TIs; 6.8% LPIs). The proportion of LPIs requiring readmission was 4.2% compared to 2.1% of TIs, (p < 0.001). The readmission rate for TIs decreased during the study period. LPIs had a higher mean cost of birth hospitalization (25,700 vs. 3300 USD; p < 0.001) and readmissions (25,800 vs. 14,300 USD; p < 0.001). For LPIs, birth hospitalization costs increased from 2007 to 2013, and decreased since 2014. Conversely, birth hospitalization costs of TIs steadily increased since 2005. The West region showed higher birth hospitalization costs for LPIs. Conclusions: LPIs continue to have a higher cost of birth hospitalization and readmission compared to TIs, but these costs have decreased since 2014. Standardization of birth hospitalization care for LPIs may reduce costs and improve quality of care and outcomes.

scholarly journals Breastfeeding Difficulties and Exclusivity Among Late Preterm and Term Infants: Results From the All Our Babies Study

2013 ◽  
Vol 104 (4) ◽  
pp. e351-e356 ◽  
Author(s):  
Tharsiya Nagulesapillai ◽  
Sheila W. McDonald ◽  
Tanis R. Fenton ◽  
Hannah Faye G. Mercader ◽  
Suzanne C. Tough
Keyword(s):  
Late Preterm ◽  
Term Infants

Predictability of transcutaneous bilirubinometry in late preterm and term infants at risk for pathological hyperbilirubinemia

2020 ◽  
pp. 1-7
Author(s):  
E. Dianova ◽  
J. Fogel ◽  
R.P. Verma
Keyword(s):  
At Risk ◽  
Serum Bilirubin Level ◽  
Late Preterm ◽  
Term Infants ◽  
Term Neonates ◽  
Transcutaneous Bilirubin ◽  
Immune Mediated ◽  
Positive Direct ◽  
Neonatal Population ◽  
Transcutaneous Bilirubinometry

BACKGROUND: The aim was to assess the predictability of transcutaneous bilirubinometry in late preterm and term neonates at risk for pathological hyperbilirubinemia, and to identify the neonatal population in which transcutaneous bilirubin most accurately predicts serum bilirubin level (SB, mg/dl). METHODS: The correlations between transcutaneous bilirubin (TCB, mg/dl) and SB in different neonatal population subsets; and between ΔTSB (TCB-SB) and relevant neonatal variables and clinical groups were analyzed. RESULTS: TCB correlated with SB (r = 0.82, p <  0.05) in the cohort (n = 350) and in population subsets (r = 0.81–0.9, p <  0.001). Black infants with gestational age (GA) >35 weeks and chronological age (CA) >3 days recorded strongest correlation (r = 0.9, p <  0.001) followed by Blacks, and non-Black infants with CA >3 days and GA >35 weeks. ΔTSB was positive in Blacks, and in infants with CA <3 days, or with no phototherapy. ΔTSB was negative in non-Blacks, in infants with positive direct Coombs test (DC+) or those receiving phototherapy. Black race [beta (SE) = 1.3(0.33), p <  0.001] had positive, while CA [beta (SE) =−1.74 (0.36), p <  0.001], DC + status [beta (SE) =−0.72 (0.25), p = 0.004] and receipt of phototherapy [beta (SE) =−0.84 (0.21), p <  0.001] each had negative correlation with ΔTSB. ΔTSB for Blacks was >Whites, Hispanics and Asians. CONCLUSION: SB is best predicted by TCB in Black infants with CA over 3 days and GA over 35 weeks. Variability in SB estimation by TCB is race, CA and immune mediated hemolysis specific.

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