scholarly journals Antifungal Potential in Crude Extracts of Five Selected Brown Seaweeds Collected from the Western Libya Coast

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Khallil AM ◽  
Daghman IM ◽  
Fady AA
Keyword(s):  
Brown Seaweeds ◽  
Crude Extracts ◽  
Antifungal Potential

scholarly journals The effect of lichen secondary metabolites on Aspergillus fungi

2021 ◽  
Vol 204 (1) ◽  
Author(s):  
Łukasz Furmanek ◽  
Paweł Czarnota ◽  
Mark R. D. Seaward
Keyword(s):  
Secondary Metabolites ◽  
Evernia Prunastri ◽  
Crude Extracts ◽  
Soxhlet Apparatus ◽  
Lichen Substances ◽  
Measuring Techniques ◽  
Antifungal Potential ◽  
Antifungal Substances ◽  
Inhibitory Potential ◽  
Aspergillus Candidus

AbstractA systematic review of literature data on the antifungal potential of extracted lichen compounds and individual secondary metabolites against mold species of the genus Aspergillus is provided. Crude extracts from 49 epiphytic, 16 epigeic and 22 epilithic species of lichens and 44 secondary metabolites against 10 species, Aspergillus candidus, A. flavus, A. fumigatus, A. nidulans, A. niger, A. ochraceus, A. parasiticus, A. restrictus, A. stellatus and A. ustus, were analysed. Several measuring techniques were employed for such analyses. Lichen substances were extracted with alcoholic and other organic solvents mainly using the Soxhlet apparatus. Among the three most-studied mold species, the results showed that the crude extracts from the thalli of the lichens Cladonia foliacea, Hypotrachyna cirrhata, Leucodermia leucomelos, Platismatia glauca and Pseudevernia furfuracea against Aspergillus flavus, from C. foliacea, Nephroma arcticum and Parmelia sulcata against A. fumigatus and from Evernia prunastri, Hypogymnia physodes, Umbilicaria cylindrica and Variospora dolomiticola against A. niger have the greatest antifungal potential. The lichen secondary metabolites showed a higher inhibitory potential, e.g. protolichesterinic acid against A. flavus, lecanoric acid against A. fumigatus and orsellinic acid against A. niger; the other seven species of Aspergillus have been poorly studied and require further investigation. A comparison of the inhibitory potential of the tested mixtures of lichen substances and their secondary metabolites shows that they can compete with commonly used antifungal substances, such as ketoconazole and clotrimazole against A. flavus, A. nidulans, A. niger and A. parasiticus and fluconazole in the case of A. fumigatus.

scholarly journals Antifungal potential of improved crude extracts of Mitracarpus scaber (Zucc) against Candida guilliermondii and Candida parapsilosis

2017 ◽  
Vol 4 (2) ◽  
pp. 90
Author(s):  
E. K. Kporou ◽  
C. Ibourahema ◽  
A. J. Ackah ◽  
S. Ouattara
Keyword(s):  
Antifungal Activity ◽  
Crude Extract ◽  
Candida Parapsilosis ◽  
Candida Guilliermondii ◽  
Dilution Method ◽  
Hydroalcoholic Extract ◽  
Crude Extracts ◽  
Antifungal Potential ◽  
Mitracarpus Scaber

Objective: The present study was undertaken to evaluate antifungal potential of improved crude extracts of Mitracarpus scaber Zucc., an ivorian traditional medicinal plant against two species of clinical yeast isolates: Candida parapsilosis and Candida guilliermondii.Methods: For evaluation of antifungal activity, double dilution method in slope tubes was used. Crude extracts of M. scaber were prepared by extracting with a blender in aqueous and hydroalcohol. In first; Aqueous (XAq) and Hydroalcoholic (X0) extracts were evaluated, and secondary the crude extract X0 was improved by partition in mixture of aqueous and hexanic solvent 50:50 v/v. Each dried phase was also examined. A phytochemical screening has been performed on most active extracts.Results: In vitro antifungal activity showed that crude extract X0 was the most active with MIC = 6.25 mg/ml. Among the extracts obtained by partition from extract X0, extract X11 (Hexanic phase) was the better with lowest antifungal parameters MIC and MFC range between 1.562 mg/ml and 0.781 mg/ml and IC50 range between 0.73 mg/ml to 0.598 mg/ml. In addition, the most active extract contained only terpens and steroids.Conclusions: Antifungal activity of M. scaber was improved by partition of an hydroalcoholic extract (X0) in mixture hexane-water 50:50 v/v. Hexanic phase (X11) was more active against C. parapsilosis and C. guilliermondii.

Phytochemical characterization of antimycobacterial crude extracts from medicinal plants traditionally used in Mozambique

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
X Luo ◽  
D Pires ◽  
JA Aínsa ◽  
B Gracia ◽  
S Mulhovo ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Crude Extracts

Bio evaluation of different crude extracts of Chrysanthimoides monilifera subsp. rotundata

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
D Reddy Kommidi ◽  
H Reddy Kandappa ◽  
B Moodley ◽  
NA Koorbanally ◽  
P Govender
Keyword(s):  
Crude Extracts

Antibacterial activity of crude extracts from Santalum spictatum and Acacia ligulata

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
D Jæger Knudsen ◽  
B Lindberg Møller ◽  
P Weinstein ◽  
S Semple
Keyword(s):  
Antibacterial Activity ◽  
Crude Extracts ◽  
Acacia Ligulata

Prevalence of antimicrobial fungal metabolites in Hydrastis canadensis crude extracts

Planta Medica ◽  
2015 ◽  
Vol 81 (11) ◽  
Author(s):  
JM Egan ◽  
A Kaur ◽  
HA Raja ◽  
AR Brown ◽  
NH Oberlies ◽  
...  
Keyword(s):  
Fungal Metabolites ◽  
Hydrastis Canadensis ◽  
Crude Extracts
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