scholarly journals Identification of an Outer Membrane Protein from Actinobacillus Pleuropneumoniae Serotype 7

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Yang J ◽  
Li L ◽  
Liu Y
Keyword(s):  
Membrane Protein ◽  
Outer Membrane ◽  
Outer Membrane Protein ◽  
Actinobacillus Pleuropneumoniae

scholarly journals fhuA of Actinobacillus pleuropneumoniae Encodes a Ferrichrome Receptor but Is Not Regulated by Iron

2003 ◽  
Vol 71 (5) ◽  
pp. 2911-2915 ◽  
Author(s):  
Leonie G. Mikael ◽  
Ramakrishnan Srikumar ◽  
James W. Coulton ◽  
Mario Jacques
Keyword(s):  
Membrane Protein ◽  
Outer Membrane ◽  
Reverse Transcription ◽  
Outer Membrane Protein ◽  
Deletion Mutant ◽  
Actinobacillus Pleuropneumoniae ◽  
Reverse Transcription Pcr ◽  
Swine Pathogen ◽  
Polyclonal Serum

ABSTRACT The swine pathogen Actinobacillus pleuropneumoniae possesses a 75-kDa outer membrane protein (OMP), FhuA, the receptor for ferrichrome, a hydroxamate-type siderophore. Polyclonal serum to FhuA reacted with OMP preparations from 12 serotypes of A. pleuropneumoniae under conditions of iron repletion and restriction. Reverse transcription-PCR confirmed that A. pleuropneumoniae fhuA expression is not upregulated in response to low iron levels. An A. pleuropneumoniae fhuA deletion mutant was generated and showed abolishment of ferrichrome uptake.

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