scholarly journals Efficacy and Safety of Moxifloxacin-Enhanced versus Standard Sequential Eradication Therapy for Treating Helicobacter pylori Infection among Tobacco Smokers

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Hasanain AF ◽  
El-Masry MA ◽  
Soliman AM ◽  
Abd-Ellatief RB ◽  
El-Sers DA
Keyword(s):  
Helicobacter Pylori ◽  
Eradication Therapy ◽  
Helicobacter Pylori Infection ◽  
Efficacy And Safety

scholarly journals Efficacy and safety of eradication therapy for elderly patients with helicobacter pylori infection

Medicine ◽  
2019 ◽  
Vol 98 (30) ◽  
pp. e16619 ◽  
Author(s):  
Satoshi Kobayashi ◽  
Satoru Joshita ◽  
Chikara Yamamoto ◽  
Takumi Yanagisawa ◽  
Takayuki Miyazawa ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Elderly Patients ◽  
Eradication Therapy ◽  
Helicobacter Pylori Infection ◽  
Efficacy And Safety

Efficacy and Safety of Vonoprazan-Based Triple Eradication Therapy for Helicobacter Pylori Infection in 890 Patients

2017 ◽  
Vol 152 (5) ◽  
pp. S249-S250
Author(s):  
Taro Akashi ◽  
Daisuke Fukuda ◽  
Yutaka Fukuda ◽  
Yuko Akazawa ◽  
Kazuhiko Nakao
Keyword(s):  
Helicobacter Pylori ◽  
Eradication Therapy ◽  
Helicobacter Pylori Infection ◽  
Efficacy And Safety

scholarly journals Diabetes mellitus as a cause of inefficiency of eradication therapy of Helicobacter pylori infection: a systematized literature review

2019 ◽  
pp. 32-38
Author(s):  
L. G. Bektemirova ◽  
D. N. Andreev ◽  
A. M. Mkrtumyan ◽  
D. T. Dicheva
Keyword(s):  
Diabetes Mellitus ◽  
Helicobacter Pylori ◽  
Eradication Therapy ◽  
Weighted Average ◽  
Interdisciplinary Approach ◽  
Helicobacter Pylori Infection ◽  
Efficacy And Safety ◽  
Patients With Diabetes ◽  
The Russian Federation ◽  
Upper Gastrointestinal

Diabetes mellitus (DM) is a moderately common issue both in the world and in the Russian Federation. Consequently, an interdisciplinary approach to studying the characteristics of the course and therapeutic management of gastroenterological pathology in this group of patients, in particular,Helicobacter pyloriinfection, which is associated with a whole range of diseases of the upper gastrointestinal tract, is of special interest. The article provides a systematic review of foreign and domestic studies of the efficacy and safety of various eradication regimens for Helicobacter pylori infection in patients with diabetes. In general, it was shown that the weighted average efficiency of eradication in people with diabetes was 17.7–23.8% lower than in people, who did not suffered from that disease.

scholarly journals Study on Association between Chronic Idiopathic Urticaria and Helicobacter Pylori Infection in Armed Forces Personnel

2016 ◽  
Vol 12 (2) ◽  
pp. 122-126 ◽  
Author(s):  
Md Sayeed Hasan ◽  
Md Shirajul Islam Khan ◽  
Jannatun Nayeem
Keyword(s):  
Helicobacter Pylori ◽  
Eradication Therapy ◽  
Armed Forces ◽  
Case Control ◽  
Chronic Idiopathic Urticaria ◽  
Helicobacter Pylori Infection ◽  
Enteric Infection ◽  
Clinical Disorder ◽  
Serum Igg ◽  
H Pylori

Introduction: Chronic Idiopathic Urticaria (CIU) has an estimated prevalence of 35-65% and impacts 15 to 25% of the population at some point in their lives. Studies have shown the possible involvement of Helicobacter pylori (H. pylori) infection in chronic idiopathic urticaria (CIU), but the relationship remains controversial. Objective: To quantitatively assess the association between H. pylori infection and chronic idiopathic urticaria. Materials and Methods: This was a case-control type of analytical study and 100 patients were enrolled fifty patients of CIU fulfilling inclusion criteria with no identifiable cause were taken as case and patients without urticaria were taken as control, attending in the department of Dermatology & Venereology, CMH Dhaka for treatment from May 2015 to Aug 2016. Helicobacter pylori infection was confirmed by serum IgG for H. pylori test. Results: The result showed that H. pylori infection significantly affected a high percentage of patients 30 (60%) with chronic idiopathic urticaria. Male respondents were more positive 16(53.3%) than female 14(46.7%), in the middle aged 31-50 year about 18(60%) and triple drug therapy was successful in 16(53.33%) patients in whom H. pylori was detected. Conclusion: Urticaria is a common clinical disorder with complex triggering factors. Chronic urticaria has provided evidence that enteric infection with H. pylori may induce the disease. In this case control study, it was evident that chronic idiopathic urticaria was associated with positive serum IgG for H. Pylori. A trial of H. pylori eradication therapy may be offered to patients with CIU and evidence of H. pylori infection. Journal of Armed Forces Medical College Bangladesh Vol.12(2) 2016: 122-126

scholarly journals The efficacy and safety of quadruple therapy without bismuth (concomitant therapy) in the treatment of patients with Helicobacter pylori - associated gastric and duodenal peptic ulcer disease

2019 ◽  
Vol 91 (8) ◽  
pp. 28-33 ◽  
Author(s):  
A M Veliev ◽  
I V Maev ◽  
D N Andreev ◽  
D T Dicheva ◽  
A V Zaborovskii ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Helicobacter Pylori ◽  
Side Effects ◽  
Triple Therapy ◽  
Eradication Therapy ◽  
Test System ◽  
Efficacy And Safety ◽  
Concomitant Therapy ◽  
Quadruple Therapy ◽  
H Pylori

Aim. Evaluation of the efficacy and safety of quadrupletherapy without bismuth (concomitant therapy) in patients with Helicobacter pylori - associated gastric ulcer and duodenal ulcer in the framework of a comparative research in the population of patients in Russia. Materials and methods. A prospective randomized trial was conducted, which included 210 patients with H. pylori - associated gastric/duodenal ulcer without complications. During the process of randomization, the patients were divided into three equal groups (n=70) depending on the prescribed 10-day scheme of eradication therapy (ET): the first group received the classic triple scheme (Omeprazole 20 mg 2 times a day, Amoxicillin 1000 mg 2 times a day and Clarithromycin 500 mg 2 times a day); the second group received quadruple therapy with bismuth drugs (Omeprazole 20 mg 2 times a day, Tetracycline 500 mg 4 times a day, Metronidazole 500 mg 3 times a day, Bismuth subcitrate potassium 120 mg 4 times a day); the third group received quadruple therapy without bismuth - concomitant therapy (Omeprazole 20 mg 2 times a day, Amoxicillin 1000 mg 2 times a day, Clarithromycin 500 mg 2 times a day and Metronidazole 500 mg 2 times a day). Diagnostics of H. pylori infection during screening and control of eradication was carried out via the fast urease biopsy sample test and urea breath test system. Control of the effectiveness of ET of the microorganism was carried out not earlier than 4 weeks after the end of the treatment. During the course of therapy, the frequency of development of side effects was assessed using a special questionnaire. Results and discussion. The effectiveness of triple therapy was 72.8% (ITT; 95% CI of 62.17-83.54) and 78,4% (PP; 95% CI 68.19-88.72); quadruple therapy with the preparation of bismuth - 80.0% (ITT; 95% CI 70.39-89.6) and 84,8% (PP; 95% CI, 75.96-93.73); quadruple therapy without bismuth - concomitant therapy - 84.2% (ITT; 95% CI 75.54-93.02) and 92.1% (PP; 95% CI 85.43-98.94). Quadruple therapy without bismuth was reliably more effective than the classical triple therapy in the PP selection (p=0.044883). Statistical analysis showed a tendency to poorer effectiveness of ET in patients who had previously used antibiotic therapy (OR 0.4317; 95% CI 0.1776-1.049), and in individuals with a rapid metabolism genotype - CYP2C19*1/*1 (OR 0.12; 95% CI 0.005848-2.4624). The frequency of development of side effects during the use of triple therapy was 18.5% (95% CI of 9.23-27.91), when using quadruple therapy with bismuth - 20.0% (95% CI 10.39-29.6), and with the use of quadruple therapy without bismuth - concomitant therapy - 24.2% (95% CI 13.98-34.58). Conclusion. This prospective randomized study demonstrated the high efficiency of quadruple therapy without bismuth (concomitant therapy) in the framework of eradication of H. pylori infection in Russia.

Sign in / Sign up

Export Citation Format

Share Document