scholarly journals Lead (Pb) Toxicity Trigger Schizophrenia in Battery Workers of North Region of India

2015 ◽  
Vol 2 (3) ◽  
Author(s):  
Sharma SV ◽  
Atam V ◽  
Verma A ◽  
Kumar P ◽  
Murthy RC ◽  
...  
Keyword(s):  
Pb Toxicity ◽  
Battery Workers

Toxicity levels of mercury, lead, copper, and zinc in tissue culture systems of cauliflower, lettuce, potato, and carrot

1972 ◽  
Vol 50 (5) ◽  
pp. 973-976 ◽  
Author(s):  
W. G. Barker
Keyword(s):  
Tissue Culture ◽  
Pb Toxicity ◽  
Culture Systems ◽  
Copper And Zinc

Explanted tissues of cauliflower, carrot, potato, and lettuce have been grown in media containing Zn, Cu, Hg, and Pb. Toxicity levels have been established for each of these elements and a considerable uniformity was noted. Lettuce tissue responds occasionally to high levels of Zn by making extraordinarily prolific growth, a matter that has yet to be explained.

Evaluation of pteridine metabolism in battery workers chronically exposed to lead

2006 ◽  
Vol 25 (7) ◽  
pp. 353-359 ◽  
Author(s):  
A B Engin ◽  
D Tuzun ◽  
G Sahin
Keyword(s):  
Neurological Disorders ◽  
High Performance ◽  
Aminolevulinic Acid ◽  
Control Group ◽  
Occupationally Exposed ◽  
Lead Levels ◽  
Urinary Lead ◽  
Urinary Neopterin ◽  
Battery Workers ◽  
Increased Activity

Occupationally-exposed lead affects the neuromuscular junction and might cause disturbances in the locomotor activity. This study was undertaken to evaluate pteridine metabolism, in which neurotransmitters are synthesized in battery workers. Urinary neopterin, biopterin and creatinine were measured using high performance liquid chromatography. Serum neopterin concentrations were detected by enzyme-linked immunoassay. Blood dihydropteridine reductase (DHPR) activities and delta-aminolevulinic acid (delta-ALA) were measured spectrophotometrically. Blood and urinary lead were detected by atomic absorption spectroscopy. Significantly increased blood and urinary lead levels, urinary neopterin, biopterin and delta-ALA were found in workers, while DHPR activities were indifferent compared to control group. Urinary creatinine decreased. This is the first study to demonstrate that increased activity of the pteridine pathway results in the accumulation of the neurotransmitters that may be responsible for the neurological disorders.

scholarly journals Lead Toxicity: Health Hazards, Influence on Food Chain, and Sustainable Remediation Approaches

2020 ◽  
Vol 17 (7) ◽  
pp. 2179 ◽  
Author(s):  
Amit Kumar ◽  
Amit Kumar ◽  
Cabral-Pinto M.M.S. ◽  
Ashish K. Chaturvedi ◽  
Aftab A. Shabnam ◽  
...  
Keyword(s):  
Food Chain ◽  
Health Hazard ◽  
Relevant Literature ◽  
Lead Toxicity ◽  
Toxic Heavy Metals ◽  
Potential Health ◽  
Pb Toxicity ◽  
Potential Health Hazard ◽  
Key Issues ◽  
Safe Food

Lead (Pb) toxicity has been a subject of interest for environmental scientists due to its toxic effect on plants, animals, and humans. An increase in several Pb related industrial activities and use of Pb containing products such as agrochemicals, oil and paint, mining, etc. can lead to Pb contamination in the environment and thereby, can enter the food chain. Being one of the most toxic heavy metals, Pb ingestion via the food chain has proven to be a potential health hazard for plants and humans. The current review aims to summarize the research updates on Pb toxicity and its effects on plants, soil, and human health. Relevant literature from the past 20 years encompassing comprehensive details on Pb toxicity has been considered with key issues such as i) Pb bioavailability in soil, ii) Pb biomagnification, and iii) Pb- remediation, which has been addressed in detail through physical, chemical, and biological lenses. In the review, among different Pb-remediation approaches, we have highlighted certain advanced approaches such as microbial assisted phytoremediation which could possibly minimize the Pb load from the resources in a sustainable manner and would be a viable option to ensure a safe food production system.

scholarly journals Oral Supplementation of Lead-Intolerant Intestinal Microbes Protects Against Lead (Pb) Toxicity in Mice

2020 ◽  
Vol 10 ◽  
Author(s):  
Qixiao Zhai ◽  
Dingwu Qu ◽  
Saisai Feng ◽  
Yaqi Yu ◽  
Leilei Yu ◽  
...  
Keyword(s):  
Intestinal Microbes ◽  
Pb Toxicity ◽  
Oral Supplementation

Ecogenetics of lead toxicity and its influence on risk assessment

2019 ◽  
Vol 38 (9) ◽  
pp. 1031-1059 ◽  
Author(s):  
MS Mani ◽  
SP Kabekkodu ◽  
MB Joshi ◽  
HS Dsouza
Keyword(s):  
Risk Assessment ◽  
Mechanism Of Action ◽  
Age Groups ◽  
Public Health Problem ◽  
Lead Toxicity ◽  
Dependent Manner ◽  
Pb Toxicity ◽  
Interindividual Variations ◽  
Epigenetic Biomarkers ◽  
Pb Exposure

Lead (Pb) toxicity is a public health problem affecting millions worldwide. Advances in ‘omic’ technology have paved the way to toxico-genomics which is currently revolutionizing the understanding of interindividual variations in susceptibility to Pb toxicity and its functional consequences to exposure. Our objective was to identify, comprehensively analyze, and curate all the potential genetic and epigenetic biomarkers studied to date in relation to Pb toxicity and its association with diseases. We screened a volume of research articles that focused on Pb toxicity and its association with genetic and epigenetic signatures in the perspective of occupational and environmental Pb exposure. Due to wide variations in population size, ethnicity, age-groups, and source of exposure in different studies, researchers continue to be skeptical on the topic of the influence of genetic variations in Pb toxicity. However, surface knowledge of the underlying genetic factors will aid in elucidating the mechanism of action of Pb. Moreover, in recent years, the application of epigenetics in Pb toxicity has become a promising area in toxicology to understand the influence of epigenetic mechanisms such as DNA methylation, chromatin remodeling, and small RNAs for the regulation of genes in response to Pb exposure during early life. Growing evidences of ecogenetic understanding (both genetic and epigenetic processes) in a dose-dependent manner may help uncover the mechanism of action of Pb and in the identification of susceptible groups. Such studies will further help in refining uncertainty factors and in addressing risk assessment of Pb poisoning.

Role of P-type ATPase metal transporters and plant immunity induced by jasmonic acid against Lead (Pb) toxicity in tomato

2019 ◽  
Vol 174 ◽  
pp. 283-294 ◽  
Author(s):  
Shagun Bali ◽  
Vijay Lakshmi Jamwal ◽  
Parminder Kaur ◽  
Sukhmeen Kaur Kohli ◽  
Puja Ohri ◽  
...  
Keyword(s):  
Jasmonic Acid ◽  
Plant Immunity ◽  
Metal Transporters ◽  
Pb Toxicity ◽  
P Type

Elevated inflammatory Lp-PLA2 and IL-6 link e-waste Pb toxicity to cardiovascular risk factors in preschool children

2018 ◽  
Vol 234 ◽  
pp. 601-609 ◽  
Author(s):  
Xueling Lu ◽  
Xijin Xu ◽  
Yu Zhang ◽  
Yuling Zhang ◽  
Chenyang Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Preschool Children ◽  
Cardiovascular Risk Factors ◽  
Pb Toxicity
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