scholarly journals Early Spondyloarthritis Presenting as Premenopausal Osteoporosis and Multiple Vertebral Fractures: A Case Report

2018 ◽  
Vol 6 (6) ◽  
Author(s):  
Liyanage IK ◽  
Kottahachchi DC ◽  
Navinan R ◽  
Udumalagala S ◽  
Rosa C ◽  
...  
Keyword(s):  
Case Report ◽  
Vertebral Fractures ◽  
Premenopausal Osteoporosis ◽  
Multiple Vertebral Fractures

scholarly journals Occipitosacral Fusion for Multiple Vertebral Fractures with Kyphotic Deformity in a Patient with Mutilating Rheumatoid Arthritis: A Case Report

2017 ◽  
Vol 03 (01) ◽  
pp. e48-e52
Author(s):  
Tetsu Tanouchi ◽  
Takachika Shimizu ◽  
Masatake Ino ◽  
Naofumi Toda ◽  
Nodoka Manabe ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Case Report ◽  
Early Detection ◽  
Pelvic Fracture ◽  
Clinical Assessment ◽  
Vertebral Fractures ◽  
Sagittal Alignment ◽  
Kyphotic Deformity ◽  
Osteoporotic Vertebral Fractures ◽  
Multiple Vertebral Fractures

AbstractOsteoporotic vertebral fractures are well-known complications of rheumatoid arthritis. The management of multiple vertebral fractures with kyphotic deformity is controversial. We present a case of a patient with mutilating rheumatoid arthritis who had multiple vertebral fractures with kyphotic deformity after occipitothoracic fusion for rheumatoid cervical disorder. Occipitosacral fusion was effective to create stable spine with better sagittal alignment in this case, but careful clinical assessment for early detection and management of postoperative insufficient pelvic fracture were required.

A pregnant woman with multiple vertebral fractures due to Cushing's syndrome: A case report

2021 ◽  
Author(s):  
Juri Teramoto ◽  
Akio Kanda ◽  
Itaru Morohashi ◽  
Atsuhiko Mogami ◽  
Osamu Obayashi ◽  
...  
Keyword(s):  
Case Report ◽  
Pregnant Woman ◽  
Cushing’S Syndrome ◽  
Vertebral Fractures ◽  
Cushing's Syndrome ◽  
Multiple Vertebral Fractures

Hypercalcemia, hypercortisolism and multiple vertebral fractures in a 49-year-old man

2018 ◽  
Author(s):  
Paula Fernandez-Trujillo-Comenge ◽  
Agnieszka Kuzior ◽  
Manuel Esteban Nivelo-Rivadeneira ◽  
Ana Delia Santana-Suarez ◽  
Carmen Acosta-Calero ◽  
...  
Keyword(s):  
Vertebral Fractures ◽  
Multiple Vertebral Fractures

scholarly journals Long-Term Follow-Up of Denosumab Discontinuers with Multiple Vertebral Fractures in the Real-World: A Case Series

2021 ◽  
Author(s):  
Liana Tripto-Shkolnik ◽  
Yair Liel ◽  
Naama Yekutiel ◽  
Inbal Goldshtein
Keyword(s):  
Real World ◽  
Vertebral Fractures ◽  
Clinical Laboratory ◽  
Case Series ◽  
High Risk Group ◽  
Imaging Data ◽  
Long Term Follow Up ◽  
Multiple Vertebral Fractures

AbstractDenosumab discontinuation is associated with rapid reversal of bone turnover suppression and with a considerable increase in fracture risk, including a risk for multiple vertebral fractures (MVF). Long-term follow-up of patients who sustained MVF after denosumab discontinuation has not been reported. This case-series was aimed to provide a long-term follow-up on the management and outcome of denosumab discontinuers who initially presented with multiple vertebral fractures. Denosumab discontinuers were identified from a computerized database of a large healthcare provider. Baseline and follow-up clinical, laboratory, and imaging data were obtained from the computerized database and electronic medical records. The post-denosumab discontinuers MVF patients consisted of 12 women aged 71±12. Osteoporotic fractures were prevalent before denosumab discontinuation in 6 of the patients. The majority received bisphosphonates before denosumab. MVF occurred 134±76 days after denosumab discontinuation. The patients were followed for a median of 36.5 (IQR 28.2, 42.5) months after MVF. Two patients passed-away. Two patients suffered recurrent vertebral fractures. Following MVF, patients were treated inconsistently with denosumab, teriparatide, oral, and intravenous bisphosphonates, in various sequences. Two patients underwent vertebroplasty/kyphoplasty. This long-term follow-up of real-world patients with MVF following denosumab discontinuation reveals that management is inconsistent, and recurrent fractures are not uncommon. It calls for clear management guidelines for patients with MVF after denosumab discontinuation and for special attention to this high-risk group.

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