scholarly journals “Comparative assessment of cellular proliferative potential in oral lichen planus and oral lichenoid lesions by quantitative analysis of nucleolar organizer regions”

2016 ◽  
Vol 3 (4) ◽  
pp. 118-122
Author(s):  
Sarita Yanduri ◽  
R. Janani ◽  
Veerendra B. Kumar ◽  
S. Suma ◽  
Tanu Tiwari
Oral Oncology ◽  
2006 ◽  
Vol 42 (5) ◽  
pp. 475-480 ◽  
Author(s):  
Renata Rodrigues Acay ◽  
Claudia Ronca Felizzola ◽  
Ney Soares de Araújo ◽  
Suzana Orsini Machado de Sousa

2021 ◽  
Vol 8 (2) ◽  
pp. 84-88
Author(s):  
Marwa Zohdy ◽  
Simone Cazzaniga ◽  
Helga Nievergelt ◽  
Roland Blum ◽  
Valérie G. A. Suter ◽  
...  

Oral lichen planus (OLP) and oral lichenoid lesions (OLL) can both present with histological dysplasia. Despite the presence of WHO-defined criteria for the evaluation of epithelial dysplasia, its assessment is frequently subjective (inter-observer variability). The lack of reproducibility in the evaluation of dysplasia is even more complex in the presence of a lichenoid inflammation. We evaluated dysplasia in 112 oral biopsies with lichenoid inflammation in order to study the inter-observer and the intra-observer variability.


2014 ◽  
Vol 25 (6) ◽  
pp. 461-465
Author(s):  
João Paulo De Carli ◽  
Soluete Oliveira da Silva ◽  
Maria Salete Sandini Linden ◽  
Carmen Silvia Busin ◽  
Luiz Renato Paranhos ◽  
...  

The objective of this study was to evaluate the cellular proliferative potential of oral lichen planus (OLP) lesions from patients without hepatitis C virus (HCV) by means of AgNOR method, as well as the cellular proliferative potential of the normal oral mucosa from patients with HCV, treated or untreated by interferon and ribavirin. A cross-sectional study was developed to investigate four groups: 10 HCV+ patients without clinical signs of OLP who had never been treated for HCV infection - Group 1; 10 HCV+ patients that were under interferon and ribavirin treatment - Group 2; 15 patients with reticular OLP lesions histopathologically confirmed, without HCV - Group 3; and 15 blood donors without HCV infection and no clinical signs of OLP GROUP 4 Control Group. The cytological material of all groups was collected by the liquid-based cytology technique. Then, the sedimented material from each patient was filled with the Nucleolar Organizer Regions impregnation by silver method (AgNOR). The count of NORs was performed on 100 epithelial cell nuclei per patient using the Image Tool(tm) software. The Tukey HSD test was used to compare the median value of NORs among the groups and showed that the oral mucosa of HCV+ patients previously treated with anti-HCV drugs (GROUP 2), presented a higher average number of NORs in relation to others (p<0.05). The anti-HCV treatment may be related to increased cell proliferation of oral mucosa, indicating a possible relationship between OLP and HCV+ patients treated with interferon and ribavirin.


2019 ◽  
Vol 23 (12) ◽  
pp. 4441-4448 ◽  
Author(s):  
Miriane Lucindo Zucoloto ◽  
Matheus Eiji Warikoda Shibakura ◽  
Jefferson Veronezi Pavanin ◽  
Fernanda Teixeira Garcia ◽  
Paulo Sérgio da Silva Santos ◽  
...  

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