scholarly journals PROBLEMS OF CHILDREN'S DISABILITY IN MODERN RUSSIA

2017 ◽  
Vol 72 (4) ◽  
pp. 305-312 ◽  
Author(s):  
A. A. Baranov ◽  
L. S. Namazova- Baranova ◽  
R. N. Terletskaya ◽  
E. V. Antonova
Keyword(s):  
Metabolic Diseases ◽  
Perinatal Care ◽  
Age Groups ◽  
Genetic Load ◽  
Endocrine System ◽  
Childhood Disability ◽  
Hereditary Metabolic Diseases ◽  
Services Implementation ◽  
Medical Genetic Services ◽  
Children Development

 Creation of system of early prophylaxis of children disability and support of the families bringing up disabled children and children with limited opportunities are among the main priorities of the Russian Federation state social policy. There are a number of problems requiring immediate solutions. Dynamics of children’s disability in our country is characterized by process stagnation. The age and gender structure of children’s disability practically doesn’t change. The analysis of its nosological structure shows that alienations and disorders of behavior, illness of a nervous system and congenital anomalies of development steadily occupy more than 60% among the illnesses which caused disability of children of all age groups. There was a decrease in the prevalence of total disability in most classes of diseases, such as injuries, diseases of the genitourinary system, respiratory system, musculoskeletal system, digestive system and growth of disability caused by neoplasms and diseases of the endocrine system. The underestimation of children’s disability bound to various reasons is supposed: social motivation of a family, complexity of legal veneering, strict requirements of service of medico-social examination, insufficient medical experts awareness on criteria of disability. Among disability formations risk factors the most discussed are the achievements of perinatology leading to improvement of nursing of prematurely born and small newborns, and wide uses of auxiliary genesial technologies. An important part of all preventive measures aimed at reducing the genetic load of population is prenatal and preimplantation diagnosis. It seems appropriate to extend the screening to congenital and hereditary metabolic diseases in neonatal period, including the most common nosological forms of infrequent illnesses. In solving problems of childhood disability prevention a priority should be given to development of services of family planning; improving antenatal and perinatal care; preventive work with healthy but having deviations in development children; development of medical genetic services; implementation of programs of different types of pathology screening.

scholarly journals SOME RISK FACTORS FOR THE FORMATION OF CHILDREN’S DISABILITY

2017 ◽  
Vol 20 (2) ◽  
pp. 60-64
Author(s):  
A. A Baranov ◽  
L. S Namazova-Baranova ◽  
Rimma N. Terletskaya ◽  
E. V Antonova
Keyword(s):  
Risk Factors ◽  
Metabolic Diseases ◽  
Perinatal Care ◽  
Genetic Load ◽  
Reproductive Technologies ◽  
Healthy Children ◽  
Childhood Disability ◽  
Hereditary Metabolic Diseases ◽  
Services Implementation ◽  
Online Library

The creation of the system of early prophylaxis of children disability and support of families bringing up disabled children and children with limited opportunities of health are among the main priorities of the state social policy of the Russian Federation. The search for literature sources was performed in the Scientific Online Library (eLIBRARY.RU) and PubMed. The dynamics of children’s disability in our country is characterized by the process of stagnation. Among risk factors for the formations of the disability the most discussed are achievements of perinatology leading to the improvement of nursing of prematurely born and small for date newborns, and wide uses of auxiliary reproductive technologies. An important part of all preventive measures aimed at the decline of the genetic load of population is the prenatal and preimplantation diagnosis. It seems appropriate to extend the screening for congenital and hereditary metabolic diseases in neonatal period, including the most common nosological forms of rare illnesses. In the solution of problems of the prevention of the childhood disability a priority should be given to the development of services of family planning, improvement of the antenatal and perinatal care, the preventive work with healthy children with deviations in the development, the development of medical genetic services, implementation of programs of different types of pathology screening.

GAMBARAN PENYAKIT PERIODONTAL PADA PENDERITA DIABETES MELITUS DI RUMAH SAKIT UMUM PUSAT PROF. DR. R. D KANDOU MANADO

e-GIGI ◽  
2015 ◽  
Vol 3 (2) ◽  
Author(s):  
Ezra G. R. Tambunan ◽  
Karel Pandelaki ◽  
Christy N. Mintjelungan
Keyword(s):  
Diabetes Mellitus ◽  
Periodontal Disease ◽  
Metabolic Diseases ◽  
Age Groups ◽  
Evaluation Criteria ◽  
Sampling Technique ◽  
Oral Health Problem ◽  
Result Show ◽  
Patients With Diabetes ◽  
Diabetes Melitus

Abstract: Diabetes mellitus (DM) is a group of metabolic diseases with characteristic hyperglycemia that occurs due to insulin secretion, insulin action or both. This disease affects many societies and continuously growing in Indonesia. Periodontal disease is an oral health problem which has a relatively high prevalence in the community where periodontal disease in all age groups in Indonesia.The purpose of this study was to determine the periodontal disease in patients with diabetesmellitus in RSUP Prof. dr. R. D. Kandou Manado. This descriptive study has 68 sample taken with total sampling technique. The sample is examined using evaluation criteria gingival index and CPITN index. The result show that subjects with periodontitis with a score of 4 is the highest as many as 18 people (44%) and subject with a score of 2 is that at least as many as 8 people (19.5%). And subjects with bad gingivitis is the highest as many as 10 people (52.6%) and subject with the good gingivitis is the at least as many as 5 people (26.3%). Based on the result of this study, periodontal disease in patients with diabetes mellitus in RSUP Prof. Dr. R. D. Kandou most that periodontitis with the number of 41 people (68.3%) compared to gingivitis which is just as many as 19 people (31.7%)Keywords: diabetes mellitus, periodontitis, gingivitis, periodontalAbstrak:Diabetes Melitus (DM) merupakan suatu kelompok penyakit metabolik dengan karakteristik hiperglikemia yang terjadi karena sekresi insulin, kerja insulin atau kedua-duanya. Penyakit ini merupakan penyakit yang banyak diderita kalangan masyarakat dan terus berkembang di Indonesia. Penyakit periodontal merupakan masalah kesehatan gigi dan mulut yang memiliki prevalensi cukup tinggi di masyarakat dimana penyakit periodontal pada semua kelompok umur di Indonesia.Tujuan penelitian ini adalah untuk mengetahui penyakit periodontal pada penderita diabetes mellitus di RSUP Prof. dr. R. D. Kandou Manado. Jenis penelitian ini adalah penelitian deskriptif dengan jumlah sampel 60 orang yang diambil dengan teknik total sampling. Sampel diperiksa dengan menggunakan kriteria penilaian indeks gingiva dan indeks CPITN. Hasil menunjukkan bahwa yang mengalami periodontitis dengan skor 4 adalah yang paling tinggi yaitu sebanyak 18 orang (44%), dan subjek yang mengalami skor 2 adalah yang yang paling sedikit yaitu sebanyak 8 orang (19.5%). Sedangkan yang mengalami gingivitis yang paling tinggi yaitu gingivitis buruk sebanyak 10 orang (52.6%) dan yang paling sedikit adalah yang mengalami gingivitis ringan yaitu sebanyak 5 orang (26.3%). Berdasarkan hasil penelitian ini dapat disimpulkan bahwa penyakit periodontal yang paling banyak ditemui pada penderita diabetes melitus di RSUP Prof. Dr. R. D. Kandou Manado adalah penyakit periodontitis yaitu sebanyak 41 orang (68.3%) dan yang paling sedikit adalah gingivitis yaitu sebanyak 19 orang (31.7%)Kata kunci: diabetes melitus, periodontitis, gingivitis, periodontal

A new medical Internet system in healthcare: innovation of Telegeriatrics and healthcare demands of older patients of different age groups (Preprint)

2020 ◽  
Author(s):  
Yu Gong ◽  
Jianyuan Zhou
Keyword(s):  
Cardiovascular Diseases ◽  
General Practitioners ◽  
Older Patients ◽  
Metabolic Diseases ◽  
Treatment Plan ◽  
Age Groups ◽  
The Elderly ◽  
Diagnosis And Treatment ◽  
World Health ◽  
New Model

BACKGROUND Healthcare for older patients is a worldwide challenge for public health system. A new medical Internet system in healthcare which is a new model of telegeriatrics system has been established. The key innovation is the new telegeriatrics system was conducted jointly by general practitioners in the Community Health Service Center and specialists in university teaching hospital. Unlike the typical telemedicine that has been practiced in other countries, the new model provides a solution for the key issues in telemedicine where a doctor is unable to conduct a direct physical examination and the associated potential diagnostic error. OBJECTIVE This study is to introduce the operation mechanism of the new Telegeriatrics system and analyze healthcare demands of older patients in different age groups applying the new Telegeriatrics system. METHODS 472 older patients (aged≥60) were enrolled and divided into the young older group (aged 60 to 74), the old older group (aged 75 to 89) and the very old group (aged≥90) according to the age stratification of World Health Organization. Proportion of the top 10 diseases of older patients of different age groups was analyzed. RESULTS The process of older patients’ diagnosis and treatment made by specialist and general practitioners formed a closed loop. It ensures the timeliness and effectiveness of diagnosis and treatment of older patients. The treatment effect can be observed by general practitioners and specialist can adjust the treatment plan in time. In this study, it was found that older patients in different age groups have different healthcare demands. Coronary heart disease and type 2 diabetes mellitus were found to be the main diseases of the older patients and the young older patients as well as the old older patients applying Telegeriatrics. CONCLUSIONS The new telegeriatrics system can provide convenient and efficient healthcare services for older patients and overcome the disadvantage of currently used models of telegeriatrics. Older patients in different age groups have different medical care demands. Cardiovascular diseases and metabolic diseases have become the main diseases of the elderly applying the new Telegeriatrics system. Healthcare policy makers should invest more medical resources to the prevention of cardiovascular diseases and metabolic diseases in the elderly.

scholarly journals Neighbourhood characteristics as a predictor of adherence to dietary recommendations: A population-based cohort study of Finnish adults

2020 ◽  
pp. 140349482097149
Author(s):  
Hanna Lagström ◽  
Jaana I. Halonen ◽  
Sakari Suominen ◽  
Jaana Pentti ◽  
Sari Stenholm ◽  
...  
Keyword(s):  
Population Density ◽  
Dietary Habits ◽  
Metabolic Diseases ◽  
Adult Population ◽  
Age Groups ◽  
Population Based ◽  
Dietary Recommendations ◽  
Neighbourhood Characteristics ◽  
Severe Life Events ◽  
Dietary Score

Aims: To investigate the association of six-year cumulative level of socioeconomic neighbourhood disadvantage and population density with subsequent adherence to dietary recommendations, controlling for preceding dietary adherence, in adults in Finland. Methods: Population-based Health and Social Support (HeSSup) study participants from four age groups (20–24, 30–34, 40–44 and 50–54 years at baseline in 1998). Data on diet and alcohol consumption were obtained from the 2003 and 2012 surveys and information on neighbourhoods from Statistics Finland Grid database ( n = 10,414 men and women). Participants diet was measured as adherence to Nordic Nutrition recommendation (score range 0–100). Neighbourhood disadvantage was measured by median household income, proportion of those with primary education only and unemployment rate, and population density by the number of adult population between years 2007 and 2012. Linear models were used to assess the associations of neighbourhood characteristics with the score for adherence to dietary recommendations in 2012. Results: Cumulative neighbourhood socioeconomic disadvantage was associated with slightly weaker (1.49 (95% confidence interval (CI) −1.89 to −1.09) point decrease in dietary score) adherence while higher population density was associated with better (0.70 (95% CI 0.38−1.01) point increase in dietary score) adherence to dietary recommendations. These associations remained after controlling for prior dietary habits, sociodemographic, chronic cardio-metabolic diseases, and severe life events. Conclusions: These longitudinal findings support the hypothesis that neighbourhood characteristics affect dietary habits.

COMMITTEE ON NUTRITION

PEDIATRICS ◽  
1967 ◽  
Vol 40 (2) ◽  
pp. 289-304
Author(s):  
CHARLES U. LOWE ◽  
DAVID BAIRD COURSIN ◽  
FELIX P. HEALD ◽  
MALCOLM A. HOLLIDAY ◽  
DONOUGH O'BRIEN ◽  
...  
Keyword(s):  
Metabolic Disease ◽  
Metabolic Diseases ◽  
Dietary Treatment ◽  
Nutritional Therapy ◽  
The United States ◽  
Detection Methods ◽  
Dietary Therapy ◽  
Treatment Practices ◽  
Hereditary Metabolic Diseases ◽  
Number Of Patients

THIRTEEN YEARS AGO a dietary approach to the therapy of phenylketonuria was proposed, and data on the usefulness as well as the very real limitations of this program have accumulated in the intervening years. At the present time studies on the application of special diets for use in this disease, as well as for many other hereditary metabolic diseases, are in progress. As wider use is made of procedures for detection of hereditary metabolic disease in the newborn, an increasingly larger number of patients who may benefit from appropriate nutritional therapy will be identified very early in life. For example, calculations based on the current birth rate and apparent incidence of phenylketonuria indicate that as many as 4,000 infants with this disorder in the United States alone could require dietary therapy in the next decade. There is, therefore, a need to evaluate the principles governing nutritional management of hereditary metabolic disease in order to develop optimal treatment facilities for use in conjunction with new detection methods. It seems anomalous that comparatively little has been done either to establish good treatment practices in hereditary metabolic disease or to mobilize scientific resources to ensure an optimistic out-come for therapeutic endeavors, while so much emphasis has been placed on detection. Dietary treatment of hereditary metabolic disease is simple in theory; however, practical application may be unexpectedly difficult, or even hazardous, if not carefully supervised. It should be determined whether: (1) the untreated disease is in fact harmful, (2) the treatment is useful in preventing or reversing the unfavorable progression of the disease, (3) the therapy may be harmful by interfering with growth or development, and (4) the program may be harmful to others to whom it is inadvertently or inappropriately given.

scholarly journals Aetiological aspects of west syndrome

2006 ◽  
Vol 134 (Suppl. 1) ◽  
pp. 45-49
Author(s):  
Borivoj Marjanovic ◽  
Milena Djuric ◽  
Dragan Zamurovic ◽  
Ruzica Kravljanac ◽  
Gordana Vlahovic ◽  
...  
Keyword(s):  
Metabolic Diseases ◽  
Neurological Impairment ◽  
Epileptic Encephalopathy ◽  
Psychomotor Retardation ◽  
West Syndrome ◽  
Clinical Feature ◽  
Perinatal Complications ◽  
Hereditary Metabolic Diseases ◽  
Number Of Patients ◽  
Aetiological Diagnosis

INTRODUCTION. West Syndrome involves epileptic encephalopathy in infants, occurring with an incidence of 5/10000 live births. Its main clinical feature are spasms that occur in clusters, which are associated with an EEG pattern called hypsarrhythmia and psychomotor retardation in most patients. West Syndrome is associated with many underlying conditions and the terms idiopathic, cryptogenic, and symptomatic are used for its aetiological subgroups. OBJECTIVE. The objective of this investigation was to determine the aetiological diagnosis of patients with West Syndrome and to compare the results with other studies. METHOD. In this 34-year longitudinal prospective one-centre study, 404 patients were studied. All patients exhibiting the diagnostic criteria for West Syndrome were investigated by clinical and neurological examination, EEG, ophthalmologic, psychological, metabolic, genetic, as well as neuroradiological methods, according to their particular indications. RESULTS. 36 (8.9%) patients had normal development, in whom infantile spasms occurred without any identifiable underlying cause, forming the idiopathic group. 51 patients (12.6%) with neurological impairment of unknown aetiology formed the cryptogenic group. The greatest number of patients (317 or 78.5%) formed the symptomatic group, in which neurological features and developmental delay preceded the onset of spasms. Disgenetic disorders and hereditary metabolic diseases were aetiological factors 44 (10.8%) patients. Prenatal and perinatal aetiological factors were revealed in one third of the patients (134 or 31%). Postnatal aetiological factors were revealed in 42 (10.2%) patients. In our study, disgenetic disorders were registered less frequently and perinatal complications more frequently than in other studies. CONCLUSION. Our results indicate the possibility of preventing West Syndrome with good quality obstetric and neonatal care, as well as the early prenatal diagnosis of brain malformations. Modern, sophisticated investigation makes the more accurate aetiological diagnosis of West Syndrome possible.

scholarly journals LIPID METABOLISM DISEASES BY EXAMPLE GM2 GANGLIOZIDOSIS AND PREDISPOSITION TO THEM OF CERTAIN ETHNIC GROUPS OF PEOPLE

2020 ◽  
Vol 3 (2(71)) ◽  
pp. 34-36
Author(s):  
Z.V. Zyukina ◽  
T.A. Lobaeva
Keyword(s):  
Ethnic Groups ◽  
Metabolic Diseases ◽  
Scientific Literature ◽  
Research Result ◽  
The United States ◽  
Eastern European ◽  
Gm2 Gangliosidosis ◽  
Ashkenazi Jews ◽  
Hereditary Metabolic Diseases ◽  
Analytical Review

The relevance of the study is due to the fact that the scientific literature does not have sufficient data on the predisposition of certain ethnic groups of people to metabolic diseases on the example of GM2 gangliosidosis, so the purpose of the work is to clarify and analyze this predisposition of some ethnic groups of people to Tey — Sachs disease (GM2 gangliosidosis, amaurotic idiocy). The research materials and methods are a scientific and analytical review of modern publications on this topic. Research result: a review of the scientific literature has shown that the Jewish population of Eastern European origin (Ashkenazi Jews) has a higher incidence of TaySachs disease and other lipid accumulation diseases. Conclusions: the frequency of hereditary metabolic diseases ranges from 1: 2000 newborns to 1:1000000, and many of these diseases are characterized by differences in the frequency of occurrence in different ethnic groups and populations. In relation to GM2 gangliosidosis, it is shown that 1 in 27-30 Ashkenazi Jews in the United States is a recessive carrier of this disease. BTS affects 1 in 3,600 newborn Jews. One in 20 Jews have a hereditary predisposition to the disease.

MODELS AND METHODS OF INFORMATION TECHNOLOGY OF ADVANCED NEONOTAL SCREENING

2021 ◽  
Vol 6 ◽  
pp. 129-147
Author(s):  
Yekaterina Kovalоva ◽  
◽  
Vladimir Lyfar ◽  
◽  
Keyword(s):  
Information Technology ◽  
Neonatal Screening ◽  
Metabolic Diseases ◽  
Block Diagram ◽  
Information Model ◽  
Blood Analysis ◽  
Hereditary Diseases ◽  
Information Support ◽  
Information Flows ◽  
Hereditary Metabolic Diseases

The paper considers the problems of informational implementation of neonatal screening of newborns in order to improve the overall picture of the nation's health and prevent the development of hereditary diseases. The methodology for solving the problems of complete neonatal screening is based on the methods and mathematical apparatus of discrete mathematics, web technologies, data warehouses, and data mining methods. An information model of the dynamic processes of neonatal screening is proposed, based on the specific processing of data presented by a tuple, which contains coherent sequential processes for obtaining the results of tests for blood analysis of newborns, conducting genetic studies and determining pathologies and deviations from an expanded list (currently up to 44 indicators for the purpose of exiting for more than 60). The block diagram of information support of information technology in the decision support system for carrying out neonatal screening of hereditary metabolic diseases is presented. On the basis of LLC «CDC «PHARMBIOTEST», the research of the algorithm for performing sequential procedures of neonatal screening was carried out. The described algorithm of actions has been tested and fully tested for the continuity of information flows, the stability of the information model graph. As a result of the research, the sufficiency and completeness of the chronological indicators of the processing of information flows have been proved. The criteria for confirming the authenticity of methods for obtaining a diagnosis have been developed.

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