Modern Tendencies of the Use and Development of Drugs of Bacteriophages

2021 ◽  
Vol 76 (4) ◽  
pp. 351-360
Author(s):  
Elena O. Bakhrushina ◽  
Maria N. Anurova ◽  
Andrey V. Aleshkin ◽  
Natalia B. Demina ◽  
Ivan I. Krasnyuk ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Russian Federation ◽  
Industrial Production ◽  
Medication Administration ◽  
Cosmetic Products ◽  
Scientific Publications ◽  
Pharmaceutical Development ◽  
Russian Industry ◽  
The Russian Federation ◽  
First Time

The article discusses the main uses of bacteriophages as an alternative or supplement to antibiotic therapy. The authors characterize the drugs of bacteriophages and perfume and cosmetic products containing bacteriophages presented on the pharmaceutical market of the Russian Federation. Prospects and algorithms for the extemporal manufacture of medicinal forms with bacteriophages for personalized therapy, developed in countries of Europe, USA, China, Russian Federation are considered. The analysis of scientific publications on the main international databases shows the interest of the developers in the problem of the creation of new bacteriophages preparations with stable titer in different medicinal forms for routes of medication administration. One of the problems of pharmaceutical development of such products is the insufficient regulatory framework. It was noted that for the first time in the State Pharmacopoeia of the Russian Federation a general pharmacopaedic article Bacteriophages medicinal-prophylactic and private pharmacopaedic articles about the main bacteriophages and their cocktails produced by the Russian industry were introduced. It has been shown that expansion of the range of medicinal forms and ways of introducing bacteriophages, extemporal manufacture of effective and stable preparations along with their industrial production an attainable task.

Industrial Output in the USSR and Russia, 1861—2012. Part I. Reconstruction of Basic Time-series

2013 ◽  
pp. 59-83 ◽  
Author(s):  
S. Smirnov
Keyword(s):  
Time Series ◽  
Russian Federation ◽  
Industrial Production ◽  
Russian Empire ◽  
Industrial Output ◽  
Official Statistics ◽  
The Russian Federation ◽  
The Russian Empire ◽  
First Time ◽  
Official Data

The trajectory of the industrial output of the Russian empire/the USSR/ the Russian Federation for more than 150 years has been carefully investigated through official statistics as well as dozens of alternative estimates made by Russian and foreign experts. Alternative estimates are compared with official data and the usefulness and credibility of the latter are determined. Official figures for Russian industrial production for 1941—1945 as well as the time-series for1887—1926 as constructed by V. Varzar have been retrieved from the archives and are being introduced here for the first time.

On the issue of improving the legal framework in the framework of the system of children health in the Russian Federation (review)

2021 ◽  
pp. 28-44
Author(s):  
Oksana Borisovna Karpova ◽  
Anna Anatolyevna Zagoruichenko
Keyword(s):  
Child Health ◽  
Russian Federation ◽  
Maternal And Child Health ◽  
The State ◽  
State Of Health ◽  
Scientific Publications ◽  
Legal Provisions ◽  
Mothers And Children ◽  
The Russian Federation ◽  
And Child Health

The state of maternal and child health plays a key role in promoting and protecting public health. The article analyzes and summarizes the results of the analysis of legislative support for maternal and child health. The analysis of individual indicators that determine the current state of medical organizations ‘activities is presented. The purpose of the study is to determine the current directions for improving the system of maternal and child health in Russia. Materials and methods. The following methods were used: information and analytical, content analysis, comparative analysis, and statistical analysis. Sources of primary information — scientific publications, Rosstat data, regulatory legal materials. Results and discussion. Proposals for the use of the current legislation of the Russian Federation in protecting the health of mothers and children are identified. There is a need to improve the use of the current regulatory and legislative framework to improve individual indicators of the state of health of mothers and children. The analysis showed that positive results were achieved in 2012–2019 in the Russian Federation in terms of improving maternal and child health. Conclusion. The implementation of regulatory legal provisions in this area should be based on a comprehensive coordination of all activities between various departments and structures, regional characteristics of the state of health of mothers and children and such areas as prevention of neglect, medical and social assistance to orphans and children left without parental care, maintaining a healthy lifestyle and providing the children’s population with sanatorium-resort medical organizations should be taken into account.

scholarly journals About the Results of Monitoring Researches of Ballast Waters and Data of Identification of the Vibrioes Strains Selected During the Ships Researches in Russian Seaports in 2018

2020 ◽  
Vol 97 (1) ◽  
pp. 55-61
Author(s):  
S. Yu. Vodyanitskаyа ◽  
O. V. Sergienko ◽  
N. G. Ivanova ◽  
V. V. Balachnova ◽  
I. V. Arkhangelskаya ◽  
...  
Keyword(s):  
Russian Federation ◽  
Ballast Water ◽  
International Convention ◽  
International Standard ◽  
E Coli ◽  
Ballast Waters ◽  
Rostov Region ◽  
Intestinal Infections ◽  
The Russian Federation ◽  
First Time

Relevance. In September, 2017 the International Convention on Control of Ships’ Ballast Waters and sediments, in which the Russian Federation takes part, came into effect.Aim of article is to cover the results of implementation of the Convention in Russia, regarding selection and analysis of ballast waters tests for compliance with the international standard.Material and methods. The materials for work were data on ship arrivals at the international seaports of the Russian Federation, provided by sanitary and quarantine departments of the Russian ports, and monitoring researches of ballast waters in seaports of some regions of the Russian Federation. Analytical, bacteriological, molecular methods were applied.Results. The studies of ballast waters in the Leningrad and Kaliningrad regions have been conducted for the first time in 2018, and in the Rostov region the study lasts since 2010. The laboratory researches of ships’ ballast showed that E. coli, Enterococcus spp. were in norm, V. cholerae O1 and O139 in ballast were absent. 12 of 21 ballast water tests investigated by specialists of the Rostov region laboratories contained V. cholerae non-O1/non-O139, ballast was taken on the ships which arrived from Romania and Turkey.Сonclusion. The results of the molecular and genetic researches suggest that there is a probability of V. сholeraе introduction brougth with ship ballast. Management decisions are demanded to ensure biological safety of shipping and to decrease intestinal infections incidence in residents of the seaside cities.

scholarly journals Constitution and Modernization of Legislation: Proceedings of the XV International School of Young Legal Scholars (Moscow, May 27 – June 5, 2020)

2020 ◽  
Author(s):  
A.Ya. Kapustin ◽  
I.I. Kucherov ◽  
S.A. Sinitsyn ◽  
A.I. Kovler ◽  
Yu.N. Kashevarova
Keyword(s):  
Russian Federation ◽  
Comparative Law ◽  
International School ◽  
International Union ◽  
A Value ◽  
The Russian Federation ◽  
The Government ◽  
Legal Understanding ◽  
First Time ◽  
Epidemiological Situation

Modern constitutional transformations, asserting a “value” legal understanding, actualize theoretical and practical problems of legislative regulation, serve as a prereq- uisite for rethinking the essence, role and significance of law in the life of society, and determine the formulation of a number of issues related, first of all, to the qualitative implementation of novelties. This collection reflects the diversity and depth of scientific discussions of the XV In- ternational school of young legal scholars on the topic “Constitution and modernization of legislation”, which was held by the Institute of legislation and comparative law under the Government of the Russian Federation in cooperation with the International Union of lawyers. In the context of a difficult epidemiological situation related to the spread of corona- virus infection, in order to protect the health of conference participants, the organizing Committee decided to hold the XV School remotely (by correspondence). For the first time, all its scientific events were held online. The participants had a unique opportunity to communicate with the direct developers of amendments to the Constitution of the Russian Federation, present their reports in a new format.

scholarly journals Length of productive life the cows of Simmental breed

2021 ◽  
Vol 213 (10) ◽  
pp. 31-39
Author(s):  
L. Ignat'eva ◽  
A. Sermyagin
Keyword(s):  
Milk Yield ◽  
Russian Federation ◽  
Negative Relationship ◽  
Strong Relationship ◽  
Cattle Breeding ◽  
Productive Life ◽  
The Russian Federation ◽  
The Republic ◽  
First Time ◽  
The Relationship

Abstract. The purpose of the research was to assess the duration of the length of productive life of Simmental cows. Methods. The research was carried out on Simmental cows bred in 14 regions of the Russian Federation, the total livestock was 8 832 heads. The calculation of the heritability coefficients and correlation (genetic and paratypic) was carried out by using the programs RENUMF90 and REMLF90. Results. A fairly strong relationship was established between the duration of a productive life (months) and the age of culling (lactations) r = +0.795, the length of productive life (months) and lifetime productivity within the range of +0.669…+0.714. However, the relationship between the age of culling (lactations) and lifetime productivity is moderate, from +0.261 to +0.316. A moderate negative relationship was obtained between the age of culling (lactations) and milk yield per first lactation from –0.472 to –0.486. The average relationship was found between milk yield per first lactation and lifetime productivity from +0.567 to +0.588. Cows of the Altai Territory (3.08 lactations or 61.6 months), the Republic of Mordovia (3.38 lactations or 62.4 months) and the Lipetsk region (3.40 lactations or 65.7 months) were distinguished by low age of culling. While the greatest length of productive life was noted in animals and Bryansk (5.48 lactations or 86.9 months) and Irkutsk regions (4.57 lactations or 77.1 months). Bryansk (23 630 kg of milk), Tyumen (18 156 kg) and Irkutsk (17 751 kg) regions occupied the leading positions in lifetime productivity of cows in the sample, while the outsiders were the regions of traditional cattle breeding - Altai Territory (12658 kg of milk), the Republic of Bashkiria (12 482 kg). Scientific novelty. For the population Simmental cattle of the Russian Federation, for the first time, an assessment of selection and genetic parameters of lifelong productivity and length of productive life of Simmental cows was carried out, depending on the breeding region.

scholarly journals Analysis of problems of industry in Russian Federation.

2015 ◽  
Vol 2015 (3) ◽  
pp. 202-210
Author(s):  
Екатерина Стрижакова ◽  
Ekaterina Strizhakova ◽  
Дмитрий Стрижаков ◽  
Dmitriy Strizhakov
Keyword(s):  
Industrial Policy ◽  
Russian Federation ◽  
Industrial Production ◽  
The State ◽  
Russian Economy ◽  
Role Of The State ◽  
The Russian Federation

The analysis of the structure of industrial production in Russia, the level of profitability by type of activity, an analysis of R & D expenses, as well as trends in the development of industrial production and its prospects are given . To identify and support the key role of the state in regu-lating influence on the Russian economy as a whole, and on the development of industrial poten-tial of the country. Formed the main directions of development and implementation of industrial policy in the Russian Federation.

scholarly journals Reginal features of modern narcotization in the Russian Federation

2021 ◽  
Vol 27 (2) ◽  
pp. 79-96
Author(s):  
E. V. Shul’gina
Keyword(s):  
Drug Use ◽  
Russian Federation ◽  
Deviant Behavior ◽  
Secondary Analysis ◽  
Regional Features ◽  
Policy Measures ◽  
The Russian Federation ◽  
Academy Of Sciences ◽  
First Time ◽  
Illicit Drug Trafficking

The purpose of this work is to analyze regional characteristics of drug use in the Russian Federation in order to form a general picture of the spread of drug use in the country and to develop effective anti-drug policy measures that meet the challenges of the current drug situation. The regions of the Russian Federation that have, according to statistics, the maximum and minimum indicators of drug use are considered. The results of the analysis of current medical statistics (indicators for the number of people with the first-time established drug dependence syndrome, as well as the number of people with the first-time established diagnosis of “harmful (with harmful consequences) drug use”, the number of cases of acute drug poisoning, etc.), law enforcement statistics (indicators for the number of registered crimes in the field of illicit drug trafficking, the number of seized drugs, the structure of the most common drugs, etc.). A secondary analysis of specialized literature, as well as data from research conducted by the sector of sociology of deviant behavior of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences. The problem of drug abuse in various regions of our country does not lose its urgency to this day. The presence of a huge territory that unites numerous regions that are diverse in their characteristics causes the polarization of indicators of drug use within the country. Based on the results of the work, conclusions were obtained about the most risky regional features in the drug sphere, as well as regional features that act as a kind of protective factors against the spread of drug use.

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