Feline Lepra bei einem 5 Monate alten Kater in Deutschland

2018 ◽  
Vol 46 (04) ◽  
pp. 271-275
Author(s):  
Verena Himstedt ◽  
Nicole Dorn ◽  
Ulrich Göggerle ◽  
Thomas Rieker ◽  
Stephanie Krug
Keyword(s):  
Mycobacterium Lepraemurium

ZusammenfassungEin 5 Monate alter, 4 kg schwerer Europäisch-Kurzhaar-Kater wurde mit ulzerierten kutanen Knoten vorgestellt, die in mehreren Arealen über den gesamten Körper verteilt waren. Die serologische Untersuchung auf das feline Immunschwächevirus und das feline Leukämievirus ergab negative Befunde. Anhand des histologischen Nachweises von säurefesten Stäbchen in drei Hautbioptaten wurde die Diagnose Mykobakteriose der Haut gestellt. Mithilfe der Polymerase-Kettenreaktion ließ sich Mycobacterium lepraemurium identifizieren. Der Kater wurde nach der operativen Entfernung aller Hautknoten und einer 14,5 Wochen andauernden Therapie mit Rifampicin und Clarithromycin als geheilt eingestuft. Im Beobachtungszeitraum von 1 Jahr nach Therapieende entwickelte sich kein Rezidiv.

Detection of Interleukin-3 in the Serum of Mice Infected with Mycobacterium lepraemurium

1990 ◽  
Vol 162 (5) ◽  
pp. 1202-1204 ◽  
Author(s):  
M. Resnick ◽  
N. Roguel-Resnick ◽  
H. Bercovier ◽  
L. Levy ◽  
J. Toledo ◽  
...  
Keyword(s):  
Interleukin 3 ◽  
Mycobacterium Lepraemurium

Energy coupling mechanisms in host-grown Mycobacterium lepraemurium

1981 ◽  
Vol 59 (2) ◽  
pp. 75-82 ◽  
Author(s):  
M. Ishaque ◽  
C. Adapoe ◽  
L. Kato
Keyword(s):  
Energy Coupling ◽  
Oxidative Enzymes ◽  
Sprague Dawley ◽  
Succinate Oxidation ◽  
Sprague Dawley Rats ◽  
Mycobacterium Lepraemurium ◽  
Thiol Binding ◽  
Coupling Mechanisms ◽  
Respiratory Chain Inhibitors

Energy coupling mechanisms of Mycobacterium lepraemurium isolated from Sprague-Dawley rats lepromata were investigated. Cell-free extracts catalyzed phosphorylation coupled to the oxidation of generated NADH, added NADH, and succinate yielding P/O ratios of approximately 0.8, 0.6, and 0.4, respectively. Ascorbate oxidation alone or in the presence of cytochrome c or N,N,N′,N′-tetramethyl-p-phenylenediamine was not coupled to ATP synthesis.The oxidative phosphorylation was completely uncoupled by 2,4-dinitrophenol, 2,6-dibromophenol, pentachlorophenol, m-chlorocarbonylcyanide phenylhydrazone, dicumarol, and gramicidin at concentrations which did not cause any inhibition of oxygen uptake. While the NADH oxidation and associated phosphate esterification was markedly sensitive to rotenone and other flavoprotein inhibitors, these inhibitors had no effect, however, on the phosphorylation coupled to succinate oxidation. The respiratory chain inhibitors such as antimycin A or 2-n-heptyl-4-hydroxyquinoline-N-oxide, and cyanide were the potent inhibitors of the phosphorylation associated with the oxidation of NADH and succinate. The ATP formation coupled to the oxidation of NADH and succinate was also inhibited by oligomycin as well as by the thiol-binding agents, p-hydroxymercuribenzoate and N-ethylmaleimide. The results indicated that NADH and succinate oxidation by in vivo grown M. lepraemurium was mediated by oxidative enzymes involving first and second energy coupling sites.

Studies on Immune Response to Mycobacterium lepraemurium

1980 ◽  
Vol 62 (4) ◽  
pp. 423-432 ◽  
Author(s):  
R.G. Navalkar ◽  
P.J. Patel ◽  
M.V. Kanchana
Keyword(s):  
Immune Response ◽  
Mycobacterium Lepraemurium

scholarly journals Growth of Mycobacterium lepraemurium in Cultures of Mouse Peritoneal Macrophages1

1967 ◽  
Vol 93 (3) ◽  
pp. 1119-1131 ◽  
Author(s):  
Y. T. Chang ◽  
R. N. Andersen ◽  
Z. Vaituzis
Keyword(s):  
Mycobacterium Lepraemurium

scholarly journals Some Experiments on Cultivation of Mycobacterium lepraemurium

Repura ◽  
1971 ◽  
Vol 40 (2) ◽  
pp. 57-61
Author(s):  
MICHITARO UCHIDA ◽  
TATSUJI OGAWA
Keyword(s):  
Mycobacterium Lepraemurium
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