scholarly journals Discrete Graphical Models — An Optimization Perspective

2019 ◽  
Vol 11 (3-4) ◽  
pp. 160-429 ◽  
Author(s):  
Bogdan Savchynskyy
Keyword(s):  
Graphical Models

Bereavement or Breakup: A Network Approach to Modeling Differential Pathways into Depression

2019 ◽  
Author(s):  
Julian Burger ◽  
Margaret S. Stroebe ◽  
Pasqualina Perrig-Chiello ◽  
Henk A.W. Schut ◽  
Stefanie Spahni ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Graphical Models ◽  
Contextual Factors ◽  
Marital Disruption ◽  
Depression Symptoms ◽  
Depression Symptom ◽  
Multiple Time ◽  
Cross Sectional ◽  
Network Analyses ◽  
Within Subjects

Background: Prior network analyses demonstrated that the death of a loved one potentially precedes specific depression symptoms, primarily loneliness, which in turn links to other depressive symptoms. In this study, we extend prior research by comparing depression symptom network structures following two types of marital disruption: bereavement versus separation. Methods: We fitted two Gaussian Graphical Models to cross-sectional data from a Swiss survey of older persons (145 bereaved, 217 separated, and 362 married controls), and compared symptom levels across bereaved and separated individuals. Results: Separated compared to widowed individuals were more likely to perceive an unfriendly environment and oneself as a failure. Both types of marital disruption were linked primarily to loneliness, from where different relations emerged to other depressive symptoms. Amongst others, loneliness had a stronger connection to perceiving oneself as a failure in separated compared to widowed individuals. Conversely, loneliness had a stronger connection to getting going in widowed individuals. Limitations: Analyses are based on cross-sectional between-subjects data, and conclusions regarding dynamic processes on the within-subjects level remain putative. Further, some of the estimated parameters in the network exhibited overlapping confidence intervals and their order needs to be interpreted with care. Replications should thus aim for studies with multiple time points and larger samples. Conclusions: The findings of this study add to a growing body of literature indicating that depressive symptom patterns depend on contextual factors. If replicated on the within-subjects level, such findings have implications for setting up patient-tailored treatment approaches in dependence of contextual factors.

scholarly journals Fast Bayesian inference in large Gaussian graphical models

Biometrics ◽  
2019 ◽  
Vol 75 (4) ◽  
pp. 1288-1298
Author(s):  
Gwenaël G. R. Leday ◽  
Sylvia Richardson
Keyword(s):  
Bayesian Inference ◽  
Graphical Models ◽  
Gaussian Graphical Models

scholarly journals Bayesian graphical models for modern biological applications

2021 ◽  
Author(s):  
Yang Ni ◽  
Veerabhadran Baladandayuthapani ◽  
Marina Vannucci ◽  
Francesco C. Stingo
Keyword(s):  
Graphical Models ◽  
Cancer Genomics ◽  
Graph Structure ◽  
Biological Processes ◽  
Limited Sample ◽  
Large Networks ◽  
Bayesian Approaches ◽  
Complex Sampling ◽  
Complex Dependence ◽  
Bayesian Graphical Models

AbstractGraphical models are powerful tools that are regularly used to investigate complex dependence structures in high-throughput biomedical datasets. They allow for holistic, systems-level view of the various biological processes, for intuitive and rigorous understanding and interpretations. In the context of large networks, Bayesian approaches are particularly suitable because it encourages sparsity of the graphs, incorporate prior information, and most importantly account for uncertainty in the graph structure. These features are particularly important in applications with limited sample size, including genomics and imaging studies. In this paper, we review several recently developed techniques for the analysis of large networks under non-standard settings, including but not limited to, multiple graphs for data observed from multiple related subgroups, graphical regression approaches used for the analysis of networks that change with covariates, and other complex sampling and structural settings. We also illustrate the practical utility of some of these methods using examples in cancer genomics and neuroimaging.

Innovated scalable efficient inference for ultra-large graphical models

2021 ◽  
pp. 109085
Author(s):  
Jia Zhou ◽  
Zemin Zheng ◽  
Huiting Zhou ◽  
Ruipeng Dong
Keyword(s):  
Graphical Models

scholarly journals The First National Survey of Cadmium in Cacao Farm Soil in Colombia

Agronomy ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 761
Author(s):  
Daniel Bravo ◽  
Clara Leon-Moreno ◽  
Carlos Alberto Martínez ◽  
Viviana Marcela Varón-Ramírez ◽  
Gustavo Alfonso Araujo-Carrillo ◽  
...  
Keyword(s):  
Graphical Models ◽  
Partial Correlation ◽  
National Level ◽  
Prediction Method ◽  
Correlation Coefficients ◽  
Predictive Performance ◽  
Nationwide Survey ◽  
Critical Discussion ◽  
Cadmium Content ◽  
Soil Variables

This study represents the first nationwide survey regarding the distribution of Cd content in cacao-growing soils in Colombia. The soil Cd distribution was analyzed using a cold/hotspots model. Moreover, both descriptive and predictive analytical tools were used to assess the key factors regulating the Cd concentration, considering Cd content and eight soil variables in the cacao systems. A critical discussion was performed in four main cacao-growing districts. Our results suggest that the performance of a model using all the variables will always be superior to the one using Zn alone. The analyzed variables featured an appropriate predictive performance, nonetheless, that performance has to be improved to develop a prediction method that might be used nationwide. Results from the fitted graphical models showed that the largest associations (as measured by the partial correlation coefficients) were those between Cd and Zn. Ca had the second-largest partial correlation with Cd and its predictive performance ranked second. Interestingly, it was found that there was a high variability in the factors correlated with Cd in cacao growing soils at a national level. Therefore, this study constitutes a baseline for the forthcoming studies in the country and should be reinforced with an analysis of cadmium content in cacao beans.

Monotone dependence in graphical models for multivariate Markov chains

Metrika ◽  
2012 ◽  
Vol 76 (7) ◽  
pp. 873-885
Author(s):  
Roberto Colombi ◽  
Sabrina Giordano
Keyword(s):  
Markov Chains ◽  
Graphical Models ◽  
Monotone Dependence
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