Diastolic dysfunction of the myocardium in children with congenital heart defects after surgical correction

2015 ◽  
pp. 64-68
Author(s):  
V.M. Dudnyk ◽  
◽  
O.O. Zborovska ◽  
Keyword(s):  
Diastolic Dysfunction ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Surgical Correction

The effect of surgical correction of congenital heart defects in mothers on the health status of their newborns

2020 ◽  
Vol 20 (2) ◽  
pp. 55
Author(s):  
A.N. Aksenov ◽  
I.I. Bocharova ◽  
M.V. Troitskaya ◽  
L.S. Logutova ◽  
M.Yu. Bukina ◽  
...  
Keyword(s):  
Health Status ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Surgical Correction

scholarly journals INSTRUMENTAL ASSESSMENT OF MYOCARDIAL FUNCTION BY DOPPLER TISSUE IMAGING IN CHILDREN WITH CONGENITAL HEART DEFECTS AFTER SURGICAL CORRECTION AND ITS CORRELATION WITH GALECTIN-3 AMOUNT AS BIOLOGICAL MARKER OF CARDIAC FIBROSIS

2019 ◽  
Vol 72 (7) ◽  
pp. 1281-1287
Author(s):  
Veronika Dudnyk ◽  
Olha Zborovska ◽  
Yuilia Vyzhga ◽  
Kateryna Khromykh ◽  
Ganna Zvenigorodska ◽  
...  
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Myocardial Function ◽  
Myocardial Dysfunction ◽  
Heart Defects ◽  
Surgical Correction ◽  
Doppler Imaging ◽  
Lateral Part ◽  
Healthy Children ◽  
Galectin 3

Introduction: Speed myocardial indicators and estimation of galectin-3 presented for estimation of myocardial dysfunction in children with congenital heart defects (CHD). The aim: Evaluate myocardial function while using tissue Doppler imaging (TDI) and galectin-3 in children with CHD after surgical correction. Materials and methods: We examined 184 children. The study assessed both ventricle systolic and diastolic performance by TDI in combination with tricuspid annular plane systolic excursion (TAPSE). Additionally, systolic (S') and diastolic (ratio E/E') TDI measurements were obtained at the lateral part of mitral annular, interventricular part, and lateral part of tricuspid valve (S`ma lateral, S` ma septal, S`ta lateral та E/E' malateral, E/E' maseptal, E/E' talateral). Galectin-3 amount in serum was detected by immune enzyme method by kit «HumanGalectin-3». Results: Compared to results of the healthy children systolic TDI measurements in patients with CHD were significantly lower: S` ma lateral 7,81±0,10 сm/s vs 9,85±0,28 сm/s, S` ta lateral 9,70±0,12 сm/s vs 12,8±0,17 сm/s and TAPSE, 1,48±0,02 vs 2,14±0,03 сm/s (р<0,01). Ratio E/E' in patients with CHD were different from results of the healthy children in all myocardial segments: E/Е` ma lateral 7,45±0,21 vs 6,17±0,12, E/Е` ma septal 9,17±0,22 vs 7,54±0,13, E/Е` ta lateral 6,42 ± 0,14 vs 4,64±0,12, (р<0,05). Patients with CHD got galectin-3 content in serum 7,04±0,21 ng/ml vs 4,17±0,17 ng/ml (р<0,01) results of the healthy children. Conclusions: Analyze of TDI measurements and galectin-3 content allows evaluate myocardial dysfunction in asymptomatic patients with CHD after surgical correction.

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