scholarly journals Improvement of effectiveness in treatment for urinary tract infection in pregnant women

2021 ◽  
pp. 7-11
Author(s):  
Iu.V. Davydova ◽  
◽  
A.Y. Lymanskaya ◽  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antibiotic Therapy ◽  
Pregnant Women ◽  
Urinary Tract Infections ◽  
Asymptomatic Bacteriuria ◽  
Well Being ◽  
Complex Treatment ◽  
Tract Infections

The aim is to evaluate the effectiveness of Phytolysin Active prescription in therapy of urinary tract infections in pregnant women. Materials and methods. The efficacy of Phytolysin Active (1 capsule per day for 21 days) in the complex treatment for urinary tract infection was studied in comparison with the group of pregnant women using traditional antimicrobial therapy. The first group consisted of 27 pregnant women who received complex treatment (antibiotic therapy + Phytolysin Active), the second consisted of 25 women who used exclusively antibiotic therapy. Among pregnant women in the first group, symptomatic gestational cystitis was observed in 9 (33.3%) cases, and in the second group in 8 (32%) patients. Results. The effectiveness of combination therapy with the use of Phytolysin Active was proved by significant improvement in general well-being and disappearance of cystitis symptoms in 8 (88.9%) women compared with 5 (62.5%) patients in the treatment group who used exclusively antimicrobial drugs. After treatment with the addition of Phytolysin Active to antibiotic therapy, Escherichiaсoli pathogen, which is most often diagnosed in this pathology, was observed in 1 (3.7%) women compared to 5 (20%) cases in the second group. Also, 25 (92.6%) women of the first group had no recurrence of urinary tract infections for 3 months. Conclusions. Complex treatment of asymptomatic bacteriuria in pregnant women with the use of the drug Phytolysin Active is more effective than the use of antibiotic therapy alone, which is proved by the high rate of the pathogen elimination and absence of infection recurrence for 3 months. The synergistic action of two active components of Phytolysin Active (Polpharma) – cranberry proanthocyanidins and lactobacillus acidophilus – improves the effectiveness of treatment and prevents relapse. The study was carried out in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the Local Ethics Committee of the institution. The informed consent of women was obtained for the research. The authors declare no conflicts of interest. Key words: pregnancy, urinary tract infections, treatments, herbal medicine, cranberry, lactobacilli.

scholarly journals The efficacy of fosfomycin trometamol in prevention of postoperative urinary tract infection in pregnant women after endoscopic procedures: open clinical trial

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Mohamed Radwan ◽  
Ayman Hagras ◽  
Salah Nagla ◽  
Nareman Elhamamy ◽  
Mohammed Abou Farha
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Urinary Tract Infections ◽  
Lower Urinary Tract ◽  
Oral Antibiotic ◽  
Endoscopic Procedures ◽  
Tract Infections ◽  
Lower Urinary

Abstract Background Fosfomycin tromethamine is recommended (category B) for the treatment of urinary tract infections in pregnant women. We aimed to evaluate the efficacy of single-dose preoperative fosfomycin tromethamine in the prevention of urinary tract infection in pregnant women who underwent lower urinary tract endoscopic surgeries. Methodology The subjects of this study were pregnant women who underwent lower urinary tract endoscopic procedures. All patients received Fosfomycin tromethamine1 packet (3 g) dissolved in water the day before surgery. Routine pre- and postoperative urine analysis and urine cultures were performed when needed. Patients were monitored for urinary tract infections and the side effects of the drug. Moreover, maternal and fetal complications were monitored. Results The study was conducted on 31 pregnant women with a mean age of 24.48 ± 5.35 years. The endoscopic procedures were as follows: 28 (90.3%) DJ ureteric insertions for hydronephrosis, 2 (6.5%) urinary bladder stones, and cystoscopy (3.2%) for gross hematuria. Two (6.5%) patients had postoperative asymptomatic bacteriuria that resolved with oral antibiotic therapy. Conclusion Fosfomycin tromethamine is safe in preventing urinary tract infection and decreases the need for postoperative parenteral antibiotics in pregnant women who require lower urinary tract endoscopic procedures.

scholarly journals THE CURRENT STATE OF ANTIBIOTIC RESISTANCE AND THE COMPOSITION OF PATHOGENS OF URINARY TRACT INFECTIONS IN PREGNANT WOMEN

2018 ◽  
Vol 6 (2) ◽  
pp. 13-20 ◽  
Author(s):  
K. L. Lokshin ◽  
V. N. Shirshov ◽  
A. S. Popko ◽  
Yu. L. Demidko ◽  
N. D. Luchenkova
Keyword(s):  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Antibiotic Therapy ◽  
Pregnant Women ◽  
Urinary Tract Infections ◽  
Asymptomatic Bacteriuria ◽  
Resistance Rate ◽  
Acute Cystitis ◽  
E Coli ◽  
Tract Infections

Introduction.The main treatment component of asymptomatic bacteriuria, acute cystitis and pyelonephritis in pregnant women is antibiotic therapy, which in many patients is prescribed empirically. For successful selection of the drug, it is necessary to know both the structure of pathogens and the current profile of their antibiotic resistance.Purpose of research.The study of species composition and resistance to antibiotics of bacteria that cause urinary tract infections (UTIs) in pregnant women in the Moscow RegionMaterials and methods.The study included 104 pregnant women with uncomplicated UTIs who were observed and treated at the Lapino Clinical Hospital between 2016 and 2017. The material for bacteriological studies was the midstream portion of urine or urine collected by a catheter.Results.90 patients had asymptomatic bacteriuria, 10 had acute cystitis, and 4 had acute gestational pyelonephritis. The structure of the pathogens of UTI is presented: E. coli, Enterococcus faecalis, Klebsiella pneumoniae, Proteus spp., Staphylococcus spp., Streptococcus spp., Enterobacter cloacae. The most frequently detected pathogens were E. coli (67.3%) and E. faecalis (50%). Resistance rate of E.coli strains more than 20% was detected to ampicillin (36.4%), amoxicillin / clavulanate (23.2%), trimethoprim / sulfamethoxazole (27.4%), nalidixic acid (20.7%), cephalosporins 2 and 3 generation (respectively, 25.7% and 24.3%). Resistance rate more than 20% in Enterobacteriaceae family strains was detected to trimethoprim/sulfamethoxazole (24.4%), nalidixic acid (20.7%), cephalosporins 2 generations (21.7%). Antibiotic resistance of E.coli and other Enterobacteriaceae family taxons less than 10% was noted only with respect to carbapenems (0%) and fosfomycin (1.5% and 3.5%, respectively).Conclusions.It is expedient to use the obtained data on the composition and sensitivity profile of uropathogens in UTIs in pregnant women when choosing starting empirical antibiotic therapy. Disclosure: The study did not have sponsorship. The authors have declared no conflicts of interest.

scholarly journals Optimization of methods for the diagnosis and treatment of urinary tract infections in pregnant women

2019 ◽  
Vol 68 (5) ◽  
pp. 115-122
Author(s):  
Alexandra M. Khudovekova ◽  
Elena V. Mozgovaya
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Urinary Tract Infections ◽  
Contemporary Literature ◽  
Clinical Signs ◽  
Diagnosis And Treatment ◽  
The Past ◽  
Tract Infections

A urinary tract infection (UTI) during pregnancy remains one of the most important problems of obstetrics, urology, and nephrology. Pregnancy as physiological process contributes to UTI. This is caused by urinary clinical signs changing during pregnancy, approaches to diagnosis and treatment, as well as to the risk of developing urological, obstetric and neonatal complications. This article analyzes contemporary literature over the past 10 years.

Urinary Tract Infections

PEDIATRICS ◽  
1991 ◽  
Vol 87 (5) ◽  
pp. 746-746
Author(s):  
ELLEN F. CRAIN ◽  
JEFFREY C. GERSHEL
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Incidental Finding ◽  
Asymptomatic Bacteriuria ◽  
Positive Urine ◽  
Tract Infections

In Reply.— Dr Roscelli calls attention to the 16 infants in our sample with positive urine cultures but negative urinalyses and admission diagnoses other than urinary tract infection (UTI). These patients, Dr Roscelli suggests, could have had asymptomatic bacteriuria with a different source for their fever. Although we doubt that these infants had asymptomatic bacteriuria, in theory it is possible that the bacteriuria was not the cause of the fever. However, as Dr Roscelli states, "at this time there no way to determine if the bacteriuria is causing the patient's fever or is simply an incidental finding."

scholarly journals URINARY TRACT INFECTION IN PREGNANCY

2017 ◽  
pp. 126-140
Author(s):  
L. Lebid
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Urinary Tract Infections ◽  
Treatment And Prevention ◽  
Topical Diagnosis ◽  
Tract Infections ◽  
Prevention Of Relapse ◽  
In Pregnancy

the review contains information about modern conception of the urinary tract infections in pregnant women, the scheme of treatment and prevention of relapse in view of topical diagnosis and category of the teratogenicity of drugs on the criteria of FDA

scholarly journals Risk Indicators for Urinary Tract Infections in Low Risk Pregnancy and the Subsequent Risk of Preterm Birth

Antibiotics ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1055
Author(s):  
Dominique E. Werter ◽  
Brenda M. Kazemier ◽  
Caroline Schneeberger ◽  
Ben W. J. Mol ◽  
Christianne J. M. de Groot ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Preterm Birth ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Asymptomatic Bacteriuria ◽  
Risk Indicators ◽  
Recurrent Urinary Tract Infections ◽  
Increased Risk ◽  
Tract Infections

Symptomatic urinary tract infections are associated with preterm birth. However, data on risk indicators for urinary tract infections are limited and outdated. The research is a secondary analysis. The study was a prospective multicenter cohort study of low-risk pregnant women. Logistic regression was used to identify risk indicators for urinary tract infections. The incidence of urinary tract infections was 9.4%. Multivariate logistic regression showed that a history of recurrent urinary tract infections and the presence of asymptomatic bacteriuria in the present pregnancy were associated with urinary tract infections (resp. OR 3.14, 95%CI 1.40–7.02 and OR 1.96 95%CI 1.27–3.03). Women with a urinary tract infection were at increased risk of preterm birth compared to women without a urinary tract infection (12 vs. 5.1%; adjusted HR 2.5 95%CI 1.8–3.5). This increased risk was not found in women with the identified risk indicators (resp. 5.3% vs. 5.1%, adjusted HR 0.35 95%CI 0.00–420 and adjusted HR 1.5 95CI% 0.59–3.9). In conclusion, in low-risk pregnant women, risk indicators for urinary tract infections are: a history of recurrent urinary tract infections and the presence of asymptomatic bacteriuria. The risk of preterm birth is increased in women with a urinary tract infection in this pregnancy. However, women with recurrent urinary tract infections and asymptomatic bacteriuria this pregnancy appear not to be at increased risk of preterm birth.

scholarly journals Epidemiological, bacteriological profile and bacterial resistance of urinary tract infections at pregnant woman in prenatal consultation in African setting

2020 ◽  
Vol 9 (2) ◽  
pp. 461
Author(s):  
Koffi Abdoul Koffi ◽  
Edèle Kacou Aka ◽  
Horo Apollinaire ◽  
Alice Mlan Britoh ◽  
Jean Marie Perel Konan
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Urinary Tract Infections ◽  
Significant Risk ◽  
University Hospital ◽  
First Choice ◽  
Tract Infections

Background: Urinary tract infection is a common pathology during pregnancy due to hormonal and morphological changes. Objective of this study was to improve management of urinary tract infection during prenatal care.Methods: A total of 987 pregnant women who have been in prenatal care have freely accepted to participate in cross-sectional study carried out from 1st May 2016 to 30th April 2017 at Yopougon University Hospital (Abidjan Côte d’Ivoire) were included. Patients were submitted to questionnaire by one of investigators for epidemiological component and then physical examination was carried out by her attending physician for clinical component. Then at laboratory urine was taken for culture after dipstick test.Results: Of the 987 patients included 9.4% had a urinary tract infection of which 81.7% were asymptomatic. Significant risk factors retained were existence of a history of urinary tract infection (OR=0.46; p=0,038) and gestational age of pregnancy (OR=0.44; p=0.05). Urine culture isolated germs were mainly Escherichia Coli (51.6%) and Klebsiella pneumoniaie (23.6%). These germs were all susceptible to cephalosporins. They had resistances of more than 50% to penicillins.Conclusions: Escherichia coli and Klebsiella pneumoniae are most common germs of urinary tract infections in pregnant women. Escherichia coli is not susceptible to penicillins with a resistance of 70% for penicillins except for clavulanic acid amoxicillin. It appears as first choice antibiotic for our prescriptions in case of probabilistic antibiotic therapy.

scholarly journals The Effect of Theory of Planned Behavior-Based Education in Adopting the Urinary Tract Infection Prevention Behavior in Pregnant Women: A Randomized Controlled Trial

2020 ◽  
Author(s):  
Sheida Moradpour ◽  
Hossein Shahnazi ◽  
Akbar Hassanzadeh
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Theory Of Planned Behavior ◽  
Pregnant Women ◽  
Planned Behavior ◽  
Urinary Tract Infections ◽  
Educational Intervention ◽  
Behavior Based ◽  
Tract Infections

Abstract Background: Urinary tract infection (UTI) is a common infection in women, and it is more likely to occur during pregnancy due to mechanical and hormonal changes in pregnant women. Urinary tract infections can cause many complications for both mother and fetus. Given the roles of health behavior in the prevention of urinary tract infections and the nature of the theory of planned behavior-based education in behavioral change, the present study aimed to determine the effect of the theory of planned behavior-based education in teaching the urinary tract infection prevention behavior in pregnant women.Methods: The present study was a randomized controlled trial in which 100 pregnant women, who visited the comprehensive health service centers of Zarinshahr City, were randomly divided into two groups, intervention and control, containing 50 individuals. The data collection tools were a urine test and a questionnaire designed based on the theory of planned behavior. Five education sessions were held based on the constructs of the theory of planned behavior. We analyzed the effect of education review and data using independent t-tests, Mann-Whitney test, chi-square test, and repeated measures ANOVA (analysis of variance) one and three months after the educational intervention.Results: After implementing the educational intervention, the mean scores of knowledge and constructs of the theory of planned behavior significantly increased in the intervention group over time (P <0.001), while the difference was not significant in the control group over time. After the educational intervention, the incidence of urinary tract infections was 4.3 % in the intervention group and 21.3% in the control group.Conclusion: Given the positive effect of education based on the theory of planned behavior in changing the pregnant mothers' behavior, the theory can be used as a suitable intervention framework for implementing the educational programs to prevent urinary tract infections.Trial registration: Name: Iranian Registry of Clinical Trials. Registration number: IRCT20170214032575N1. Registration date: 2019-12-12 [retrospectively registered].

scholarly journals Urinary tract infections in obstetrics and gynecology: current issues of diagnosis and antibiotic therapy

2020 ◽  
Vol 68 (6) ◽  
pp. 19-28
Author(s):  
Tatyana A. Khusnutdinova
Keyword(s):  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antibiotic Therapy ◽  
Urinary Tract Infections ◽  
Clinical Manifestations ◽  
Clinical Importance ◽  
Obstetrics And Gynecology ◽  
Tract Infections

Urinary tract infections are among the most common infectious diseases in women and often complicate the course of pregnancy. This article reviews current scientific and methodical literature on the management of pregnant women with urinary tract infection. Aspects of clinical importance of urinary tract infections during pregnancy (epidemiology, clinical manifestations, and complications) are discussed, with current recommendations for diagnosis and management of urinary tract infections summarized. Special attention is paid to the problem of antibiotic resistance of urinary tract infection pathogens.

Risk Factors in Diabetes and Pregnant Women with Urinary Tract Infections Compared to Younger Aged Female.

2018 ◽  
Vol 1 (3) ◽  
pp. 26-38
Author(s):  
Abdulghani Mohamed Alsamarai ◽  
Shler Ali Khorshed
Keyword(s):  
Risk Factors ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Female Student ◽  
Mean Value ◽  
Infected Female ◽  
Significant Difference ◽  
Tract Infections

Background: Urinary tract infection is common with health impact in women and characterised by failure to treatment and recurrent episodes. Aim: This study was conducted to determine the risk factors for the development of urinary tract infection in diabetic and pregnant women in comparison to student female. Materials and methods: A prospective cross-sectional study conducted during the period from 1st of June 2015 to the end of January 2016. The population included in the study are 563 women, of them 425 were outpatients, and 138 were inpatients. Their age range between 18 and 80 years, with a mean age of 33.59±15.29 years. Urine samples collected and cultured on blood agar and MacConkey agar by spread plate technique. Bacterial colonies with different morphology were selected, purified and identified according to their biochemical characteristics using conventional standard methods. Results: In diabetic women, there were no significant difference in mean age and BMI values between culture positive and culture negative groups. However, pus cell mean scale was significantly higher [P=0.000] in women with urinary tract infection [1.76±1.25] than in those with negative culture [0.69±1.00]. In pregnant women, BMI mean value was significantly [P=0.013] lower in pregnant women with UTI [26.14] as compared to those without infection [26.99]. Pus cell scale mean value was significantly [P=0.000] higher in pregnant women with UTI [1.55] than women with negative UTI [0.85]. While there was no significant difference in mean age between UTI positive and negative pregnant women. In female student, there was a significant difference between UTI infected and non-infected in mean age [P=0.041] and pus cell scale [P=0.000]. However, BMI was not significantly different between infected and non-infected female student. Other risk factors association are variables in the 3 groups when analysed using X2, while AUC and OR show different trends of association between risk factors and UTI. Conclusion: BMI, pus cell scale, child number, delivery method, operation history and hospital setting were significantly associated with culture positivity in the 3 studied groups as determined by AUC. While OR confirmed association with pus sale scale in the 3 groups.

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