Interaction of Alpha Particle Beams with Fe-Based and FeNi-Based Glassy Ferromagnets

1995 ◽  
Vol 396 ◽  
Author(s):  
Monica Sorescu ◽  
D. Barb

AbstractSamples of Fe78B13Si9 and Fe40Ni38Mo4B18 metallic glasses were irradiated with alpha particle beams (W=2.8 MeV) using radiation doses of 1016 and 1017 cm-2. Irradiation-induced effects on the magnetic texture and phase composition of alloy samples were studied by Mössbauer spectroscopy. Related morphological changes and resultant crystalline precipitates were characterized by scanning electron microscopy. The evolution of phases and microstructure during the radiation-induced amorphous-to-crystalline transformation was found to depend on the particle flux and sample composition. The lowest radiation dose employed was found to be more effective in inducing amorphous-to-crystalline transformations in both ferromagnetic alloys studied. In addition, the FeNi-based amorphous system investigated was found to be more stable than the Fe-based metallic glass, exposed to the same particle-beam irradiation conditions. By stimulating unconventional pathways for the crystallization process, the interaction of alpha particle beams with glassy ferromagnets offers unique opportunities to understand the fundamentals of nucleation and growth in amorphous magnets.

1996 ◽  
Vol 438 ◽  
Author(s):  
Monica Sorescu ◽  
D. Barb

AbstractSamples of Fe78B13Si1 and Fe66Co18B15Si1 metallic glasses were irradiated with alpha particle beams (W=2.8 MeV) using radiation doses of 1016 and 1017 cm2. Irradiation-induced effects on the magnetic and structural properties of alloy samples were studied by transmission and conversion electron Mbssbauer spectroscopy. The evolution of phases and microstructure during the radiation-induced amorphous-to-crystalline transformation was found to depend on the particle flux and sample composition. Differences between bulk and surface irradiation behaviors were demonstrated.


2004 ◽  
Vol 851 ◽  
Author(s):  
Monica Sorescu

ABSTRACTIn view of the potential use of amorphous magnets as radiation-resistant materials, we performed a comparative study between laser and particle beam induced effects in amorphous alloy systems. We irradiated Fe81B13.5 Si3.5C2, Fe40Ni38Mo4B18, Fe66Co18B15Si1 and Fe72.6Cr22Al4.8Si0.3Y0.3 with pulsed laser radiation as well as with high (W=7 MeV) and low energy (W=30 and 50 keV) electrons and with 2.8 MeV alpha particles. The irradiation effects in these systems were investigated using several complementary techniques: transmission and conversion electron Mössbauer spectroscopy, magnetometry and electron microscopy. We were able to deduce details of the mechanism of magnetic texture formation and of the amorphous-to-crystalline phase transformations in the studied amorphous alloys.


Author(s):  
Bagher Farhood ◽  
Gholamreza Hassanzadeh ◽  
Peyman Amini ◽  
Dheyauldeen Shabeeb ◽  
Ahmed Eleojo Musa ◽  
...  

Aim: In this study, we aimed to determine possible mitigation of radiationinduced toxicities in the duodenum, jejunum and colon using post-exposure treatment with resveratrol and alpha-lipoic acid. Background: After the bone marrow, gastrointestinal system toxicity is the second critical cause of death following whole-body exposure to radiation. Its side effects reduce the quality of life of patients who have undergone radiotherapy. Resveratrol has an antioxidant effect and stimulates DNA damage responses (DDRs). Alpha-lipoic acid neutralizes free radicals via the recycling of ascorbic acid and alpha-tocopherol. Objective: This study is a pilot investigation of the mitigation of enteritis using resveratrol and alpha-lipoic acid following histopathological study. Methods: 60 male mice were randomly assigned to six groups; control, resveratrol treatment, alpha-lipoic acid treatment, whole-body irradiation, irradiation plus resveratrol, and irradiation plus alpha-lipoic acid. The mice were irradiated with a single dose of 7 Gy from a cobalt-60 gamma-ray source. Treatment with resveratrol or alpha-lipoic acid started 24 h after irradiation and continued for 4 weeks. All mice were sacrificed after 30 days for histopathological evaluation of radiation-induced toxicities in the duodenum, jejunum and colon. Results and Conclusion: Exposure to radiation caused mild to severe damages to vessels, goblet cells and villous. It also led to significant infiltration of macrophages and leukocytes, especially in the colon. Both resveratrol and alpha-lipoic acid were able to mitigate morphological changes. However, they could not mitigate vascular injury. Conclusion: Resveratrol and alpha-lipoic acid could mitigate radiation-induced injuries in the small and large intestine. A comparison between these agents showed that resveratrol may be a more effective mitigator compared to alpha-lipoic acid.


2014 ◽  
Vol 29 (10) ◽  
pp. 1372 ◽  
Author(s):  
Yongkan Ki ◽  
Wontaek Kim ◽  
Heunglae Cho ◽  
Kijung Ahn ◽  
Youngmin Choi ◽  
...  

2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Tien T Tang ◽  
Janice A Zawaski ◽  
Shelli R Kesler ◽  
Christine A Beamish ◽  
Wilburn E Reddick ◽  
...  

Abstract Background Cranial radiotherapy (CRT) is an important part of brain tumor treatment, and although highly effective, survivors suffer from long-term cognitive side effects. In this study we aim to establish late-term imaging markers of CRT-induced brain injury and identify functional markers indicative of cognitive performance. Specifically, we aim to identify changes in executive function, brain metabolism, and neuronal organization. Methods Male Sprague Dawley rats were fractionally irradiated at 28 days of age to a total dose of 30 Gy to establish a radiation-induced brain injury model. Animals were trained at 3 months after CRT using the 5-choice serial reaction time task. At 12 months after CRT, animals were evaluated for cognitive and imaging changes, which included positron emission tomography (PET) and magnetic resonance imaging (MRI). Results Cognitive deficit with signs of neuroinflammation were found at 12 months after CRT in irradiated animals. CRT resulted in significant volumetric changes in 38% of brain regions as well as overall decrease in brain volume and reduced gray matter volume. PET imaging showed higher brain glucose uptake in CRT animals. Using MRI, irradiated brains had an overall decrease in fractional anisotropy, lower global efficiency, increased transitivity, and altered regional connectivity. Cognitive measurements were found to be significantly correlated with six image features that included myelin integrity and local organization of the neural network. Conclusions These results demonstrate that CRT leads to late-term morphological changes, reorganization of neural connections, and metabolic dysfunction. The correlation between imaging markers and cognitive deficits can be used to assess late-term side effects of brain tumor treatment and evaluate efficacy of new interventions.


2016 ◽  
Vol 115 ◽  
pp. 113-124 ◽  
Author(s):  
C. Duchemin ◽  
M. Essayan ◽  
A. Guertin ◽  
F. Haddad ◽  
N. Michel ◽  
...  

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