A Flexible Accelerometer System for Human Pulse Monitoring

2014 ◽  
Vol 1690 ◽  
Author(s):  
Yuanfeng Zhang ◽  
Woo Soo Kim
Keyword(s):  
Parallel Plate ◽  
High Sensitivity ◽  
Cost Effective ◽  
The Body ◽  
Light Weight ◽  
Capacitive Sensing ◽  
Direct Printing ◽  
Voltage Output ◽  
Highly Sensitive ◽  
Weight Sensor

ABSTRACTHere we introduce a cost-effective and highly sensitive flexible accelerometer system, which can sense human pulse by detecting the pulsation. The accelerometer employs capacitive sensing with a structure of two parallel plate electrodes with the optimally designed top electrode pattern in order to achieve high sensitivity. This flexible light-weight sensor is fabricated by direct-printing of silver nano-inks on pre-patterned flexible paper substrates. When the accelerometer is attached to the body surfaces: neck, inner elbow, or any other pulsation point, accurate pulse rates are obtained by reading out the voltage output signal.

scholarly journals Printable, Highly Sensitive Flexible Temperature Sensors for Human Body Temperature Monitoring: A Review

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Yi Su ◽  
Chunsheng Ma ◽  
Jing Chen ◽  
Huiping Wu ◽  
Weixiang Luo ◽  
...  
Keyword(s):  
Body Temperature ◽  
Human Body ◽  
High Sensitivity ◽  
Measurement Range ◽  
Temperature Sensors ◽  
Temperature Monitoring ◽  
The Body ◽  
Temperature Changes ◽  
Practical Applications ◽  
Highly Sensitive

Abstract In recent years, the development and research of flexible sensors have gradually deepened, and the performance of wearable, flexible devices for monitoring body temperature has also improved. For the human body, body temperature changes reflect much information about human health, and abnormal body temperature changes usually indicate poor health. Although body temperature is independent of the environment, the body surface temperature is easily affected by the surrounding environment, bringing challenges to body temperature monitoring equipment. To achieve real-time and sensitive detection of various parts temperature of the human body, researchers have developed many different types of high-sensitivity flexible temperature sensors, perfecting the function of electronic skin, and also proposed many practical applications. This article reviews the current research status of highly sensitive patterned flexible temperature sensors used to monitor body temperature changes. First, commonly used substrates and active materials for flexible temperature sensors have been summarized. Second, patterned fabricating methods and processes of flexible temperature sensors are introduced. Then, flexible temperature sensing performance are comprehensively discussed, including temperature measurement range, sensitivity, response time, temperature resolution. Finally, the application of flexible temperature sensors based on highly delicate patterning are demonstrated, and the future challenges of flexible temperature sensors have prospected.

scholarly journals Development of a Tandem Repeat-Based Polymerase Chain Displacement Reaction Method for Highly Sensitive Detection of ‘Candidatus Liberibacter asiaticus’

2018 ◽  
Vol 108 (2) ◽  
pp. 292-298 ◽  
Author(s):  
Binghai Lou ◽  
Yaqin Song ◽  
Moytri RoyChowdhury ◽  
Chongling Deng ◽  
Ying Niu ◽  
...  
Keyword(s):  
Tandem Repeat ◽  
High Sensitivity ◽  
Cost Effective ◽  
Detection Methods ◽  
Displacement Reaction ◽  
Candidatus Liberibacter Asiaticus ◽  
Highly Sensitive ◽  
Candidatus Liberibacter ◽  
Liberibacter Asiaticus ◽  
Polymerase Chain

Huanglongbing (HLB) is one of the most destructive diseases in citrus production worldwide. Early detection of HLB pathogens can facilitate timely removal of infected citrus trees in the field. However, low titer and uneven distribution of HLB pathogens in host plants make reliable detection challenging. Therefore, the development of effective detection methods with high sensitivity is imperative. This study reports the development of a novel method, tandem repeat-based polymerase chain displacement reaction (TR-PCDR), for the detection of ‘Candidatus Liberibacter asiaticus’, a widely distributed HLB-associated bacterium. A uniquely designed primer set (TR2-PCDR-F/TR2-PCDR-1R) and a thermostable Taq DNA polymerase mutant with strand displacement activity were used for TR-PCDR amplification. Performed in a regular thermal cycler, TR-PCDR could produce more than two amplicons after each amplification cycle. Sensitivity of the developed TR-PCDR was 10 copies of target DNA fragment. The sensitive level was proven to be 100× higher than conventional PCR and similar to real-time PCR. Data from the detection of ‘Ca. L. asiaticus’ with filed samples using the above three methods also showed similar results. No false-positive TR-PCDR amplification was observed from healthy citrus samples and water controls. These results thereby illustrated that the developed TR-PCDR method can be applied to the reliable, highly sensitive, and cost-effective detection of ‘Ca. L. asiaticus’.

scholarly journals Nanoengineering of eco-friendly silver nanoparticles using five different plant extracts and development of cost-effective phenol nanosensor

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Siwar Jebril ◽  
Alaeddine Fdhila ◽  
Chérif Dridi
Keyword(s):  
Silver Nanoparticles ◽  
Water Samples ◽  
High Sensitivity ◽  
Cost Effective ◽  
Water Quality Monitoring ◽  
Melia Azedarach ◽  
Leaf Extracts ◽  
Highly Sensitive ◽  
Phenol Determination ◽  
Silver Nps

AbstractThe production of environmentally friendly silver nanoparticles (AgNPs) has aroused the interest of the scientific community due to their wide applications mainly in the field of environmental pollution detection and water quality monitoring. Here, for the first time, five plant leaf extracts were used for the synthesis of AgNPs such as Basil, Geranium, Eucalyptus, Melia, and Ruta by a simple and eco-friendly method. Stable AgNPs were obtained by adding a silver nitrate (AgNO3) solution with the leaves extract as reducers, stabilizers and cappers. Only, within ten minutes of reaction, the yellow mixture changed to brown due to the reduction of Ag+ ions to Ag atoms. The optical, structural, and morphology characteristics of synthesized AgNPs were determined using a full technique like UV–visible spectroscopy, FTIR spectrum, XRD, EDX spectroscopy, and the SEM. Thus, Melia azedarach was found to exhibit smaller nanoparticles (AgNPs-M), which would be interesting for electrochemical application. So, a highly sensitive electrochemical sensor based on AgNPs-M modified GCE for phenol determination in water samples was developed, indicating that the AgNPs-M displayed good electrocatalytic activity. The developed sensor showed good sensing performances: a high sensitivity, a low LOD of 0.42 µM and good stability with a lifetime of about one month, as well as a good selectivity towards BPA and CC (with a deviation less than 10%) especially for nanoplastics analysis in the water contained in plastics bottles. The obtained results are repeatable and reproducible with RSDs of 5.49% and 3.18% respectively. Besides, our developed sensor was successfully applied for the determination of phenol in tap and mineral water samples. The proposed new approach is highly recommended to develop a simple, cost effective, ecofriendly, and highly sensitive sensor for the electrochemical detection of phenol which can further broaden the applications of green silver NPs.

Simulation of MEMS Cantilever Biosensor and Analysis of Readout Methods for Tuberculosis Detection

2013 ◽  
Vol 376 ◽  
pp. 428-433
Author(s):  
P. Sangeetha ◽  
A. Vimala Juliet
Keyword(s):  
Early Detection ◽  
Resonant Frequency ◽  
High Sensitivity ◽  
The Body ◽  
Capacitive Sensing ◽  
Diagnostic Device ◽  
Resonant Frequency Shift ◽  
Antigen 85 ◽  
Advanced Stages ◽  
Antigen Antibody

This paper deals with designing a MEMS cantilever which can function as biosensor for tuberculosis detection. In this study we investigate the MEMS based biosensor to detect Tuberculosis based on capacitive sensing, peizoresistive and resonant frequency methods. We also examine which method has enhanced performance. Early detection and treatment of diseases can facilitated only if we are able to detect pathogenic and physiologically relevant molecules in the body with high sensitivity and specificity.Early detection of diseases reduce the risk of patients being pushed to advanced stages of many diseases.This sensor is used for early detection of Tuberculosis using the antigen antibody reaction.Tuberculosis can be detected by monitoring the presence of disease causing antigen in the blood stream.The presence of disease causing antigen in the blood can be monitered by using this microcantilever based diagnostic device. The sensing principle varies according to the device, the nature of the analyte molecules, and the precision required. Capacitance, piezoresistance and resonance frequency are among the read out methods depending upon the mechanical properties of the device. The biosensor structure is designed and simulated using Coventorware, Intellisuit and HFSS software. This microcantilever based biosensor can detect tuberculosis by immobilizing specific antibodies on the microcantilever.These antibodies are specific to TB antigen 85 complex.When the patient sample containing TB antigen 85 complex is placed on the cantilever biomolecular interactions take place between TB antigens and the antibodies immobilized on the upper surface of the microcantilever.This causes microcantilever to bend and facilitates to detect the presence of Tuberculosis.Bending of the cantilever can be measured by capacitive sensing, peizoresistive and resonant frequency shift methods.

High-sensitivity detection of gold labels by high-angle dark-field STEM imaging

1990 ◽  
Vol 48 (3) ◽  
pp. 892-893 ◽  
Author(s):  
Max T. Otten
Keyword(s):  
High Sensitivity ◽  
Dark Field ◽  
Bright Field ◽  
Backscattered Electron Imaging ◽  
Backscattered Electrons ◽  
Average Atomic Number ◽  
Highly Sensitive ◽  
Backscattered Electron ◽  
Electron Imaging ◽  
High Sensitivity Detection

Labelling of antibodies with small gold probes is a highly sensitive technique for detecting specific molecules in biological tissue. Larger gold probes are usually well visible in TEM or STEM Bright-Field images of unstained specimens. In stained specimens, however, the contrast of the stain is frequently the same as that of the gold labels, making it virtually impossible to identify the labels, especially when smaller gold labels are used to increase the sensitivity of the immunolabelling technique. TEM or STEM Dark-Field images fare no better (Figs. 1a and 2a), again because of the absence of a clear contrast difference between gold labels and stain.Potentially much more useful is backscattered-electron imaging, since this will show differences in average atomic number which are sufficiently large between the metallic gold and the stains normally used. However, for the thin specimens and at high accelerating voltages of the STEM, the yield of backscattered electrons is very small, resulting in a very weak signal. Consequently, the backscattered-electron signal is often too noisy for detecting small labels, even for large spot sizes.

Role of Rasayana in Prevention of COVID-19 - A Review

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 716-722
Author(s):  
Sneha Dhakite ◽  
Sadhana Misar Wajpeyi
Keyword(s):  
Immune System ◽  
Respiratory System ◽  
Viral Infections ◽  
Cost Effective ◽  
The Body ◽  
Healthy Life ◽  
Vital Functions ◽  
Healthy Life Style ◽  
And Control

The “Coronavirus disease 19 (COVID-19)” is caused by “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)”, a newly discovered member of the Coronaviridae family of viruses which is a highly communicable. There is no effective medical treatment till date for Coronavirus disease hence prevention is the best way to keep disease away. Rasayana proved to be highly efficacious and cost effective for the Prevention and Control of viral infections when vaccines and standard therapies are lacking. Rasayana Chikitsa is one of the eight branches of Ashtanga Ayurveda which helps to maintain healthy life style. Rasayana improves immunity and performs many vital functions of human body. Vyadhikshamatva that is immune mechanism of the body is involved in Prevention of the occurrence of a new disease and it also decreases the virulence and progression of an existing disease. In COVID-19 the Respiratory system mainly get affected which is evident from its symptoms like cold, cough and breathlessness. Here the drugs help in enhancing immune system and strengthening functions of Respiratory system can be useful. For this purpose, the Rasayana like Chyavanprasha, Agastya Haritaki, Pippali Rasayana, Guduchi, Yashtimadhu, Haridra, Ashwagandha, Tulsi are used. Rasayana working on Respiratory system are best for Prevention of Coronavirus and boosting immune system. Rasayana Chikitsa can be effective in the Prevention as well as reducing symptoms of COVID-19.

Yoga in the management of Diabetes Mellitus

2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Sreeharsha N. ◽  
Bargale Sushant Sukumar ◽  
Divyasree C. H.
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Eating Habits ◽  
Cost Effective ◽  
The Body ◽  
Positive Thinking ◽  
The World ◽  
Diabetic Population ◽  
Major Factors ◽  
Excess Glucose

Diabetes mellitus is a chronic metabolic disorder in which the body is unable to make proper utilisation of glucose, resulting in the condition of hyperglycaemia. Excess glucose in the blood ultimately results in high levels of glucose being present in the urine (glycosuria). This increase the urine output, which leads to dehydration and increase thirst. India has the largest diabetic population in the world. Changes in eating habits, increasing weight and decreased physical activity are major factors leading to increased incidence of Diabetes. Lifestyle plays an important role in the development of Diabetes. Yoga offers natural and effective remedies without toxic side-effects, and with benefits that extend far beyond the physical. This system of Yoga is a simple, natural programme involving five main principles: proper exercise, proper breathing, proper relaxation, proper diet and positive thinking and meditation. It is a cost effective lifestyle intervention technique.

scholarly journals Role of MRI evaluation in acute secondary inability to walk in children

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
K. H. Sedeek ◽  
K. Aboualfotouh ◽  
S. M. Hassanein ◽  
N. M. Osman ◽  
M. H. Shalaby
Keyword(s):  
Transverse Myelitis ◽  
High Sensitivity ◽  
Acute Disseminated Encephalomyelitis ◽  
Limb Weakness ◽  
Non Invasive ◽  
Highly Sensitive ◽  
Common Causes ◽  
Bilateral Lower Limb ◽  
Severity Of The Disease

Abstract Background Acute bilateral lower limb weakness is a common problem in children which necessitates a rapid method for diagnosis. MRI is a non-invasive imaging technique that produces high-quality images of the internal structure of the brain and spinal cord. Results MRI was very helpful in reaching rapid and prompt diagnosis in children with acute inability to walk. Acute disseminated encephalomyelitis (ADEM), Guillain–Barré syndrome (GBS), and acute transverse myelitis (ATM) were the most common causes in our study. MRI proved to be of high sensitivity in detecting the lesions and reaching the diagnosis in ADEM and GBS; however, there was no significant relation between the lesions’ size, enhancement pattern, and severity of the disease or prognosis, yet in ATM the site of the lesion and number of cord segment affection were significantly related to the severity of the disease and prognosis. Conclusion MRI is a quick tool to reach the diagnosis of children with acute secondary inability to walk, and to eliminate other differential diagnosis which is essential for proper treatment and rapid full recovery. It is highly sensitive in detecting the lesions, their site and size.

scholarly journals Highly sensitive detection of nitrobenzene by a series of fluorescent 2D zinc(ii) metal–organic frameworks with a flexible triangular ligand

RSC Advances ◽  
2021 ◽  
Vol 11 (39) ◽  
pp. 23975-23984
Author(s):  
Xue Yang ◽  
Yixia Ren ◽  
Hongmei Chai ◽  
Xiufang Hou ◽  
Zhixiang Wang ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Metal Organic Frameworks ◽  
High Sensitivity ◽  
Fluorescent Sensors ◽  
Sensitive Detection ◽  
Donor Ligands ◽  
Highly Sensitive ◽  
Metal Organic ◽  
Highly Sensitive Detection

Four fluorescent 2D Zn-MOFs based on a flexible triangular ligand and linear N-donor ligands are hydrothermally prepared and used to detect nitrobenzene in aqueous solution with high sensitivity, demonstrating their potential as fluorescent sensors.

scholarly journals Pancreatic Carcinoma Metastatic to the Gingiva

2021 ◽  
Vol 11 (1) ◽  
pp. 58-64
Author(s):  
Arijan Zubović ◽  
Margita Belušić-Gobić ◽  
David Harmicar ◽  
Jasna Marušić ◽  
Damir Vučinić ◽  
...  
Keyword(s):  
Pancreatic Carcinoma ◽  
Pancreatic Tumor ◽  
Maxillofacial Surgery ◽  
The Body ◽  
Retroperitoneal Mass ◽  
Immunohistochemical Examination ◽  
Normal Result ◽  
Highly Sensitive ◽  
Gingival Neoplasm ◽  
Malignant Lesions

Metastatic tumors to the oral cavity are uncommon, representing approximately 1% of all cases of oral malignant lesions even when a metastatic disease is present. The 53-year-old female is presented complaining of abdominal pain, weight loss, and a loose stool recurring not more than three times per day. A computed tomography (CT) scan of the abdomen showed a retroperitoneal mass expanding along the body of the pancreas. Colonoscopy and gastroscopy with a gastric mucosa biopsy showed a normal result. After laparoscopic surgery, the primary site of adenocarcinoma was not confirmed. The patient was referred to the Maxillofacial Surgery Clinic with pain, swelling, and occasional bleeding around the lower right second mollar. Immunohistochemicaly, the tumor cells were positive for Cytokeratin (CK) 19, Cytokeratin (CK) 7, and homebox protein (CDX-2), which are highly sensitive markers of pancreatobiliar cancer. Therefore, the patient was diagnosed with pancreatic carcinoma. This report describes a rare metastasis of malignant pancreatic tumor to the lower right gingiva and highlights the importance of immunohistochemical examination and how it helped identify both the origin and the nature of gingival neoplasm.

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