Detection of Protein by Reduced Graphene Oxide Field-Effect Transistor

ABSTRACTWe confirmed a specific detection of immunoglobulin E(IgE) by using an aptamer immobilized reduced graphene oxide(rGo) field effect transistor(FET). A detection limit and dynamic range were estimated 8.1 ng/ml and 10000 respectively. These characteristics are comparable with current fluorescent markers. Although a mobility of rGo FET was around 5 cm2/V.sec, and this is two to three orders lower than mechanically exfoliated pristine graphene FET, a sensitivity of it was only one order lower than using pristine graphene.