Solutochromic Molecular Spectroscopy with a Reference Hydrogen-Bond Acid Dendrimer

2012 ◽  
Vol 1403 ◽  
Author(s):  
R. Andrew McGill ◽  
Duane Simonson ◽  
Julie H. Ta ◽  
Viet Nguyen ◽  
Yasar Ozten ◽  
...  
Keyword(s):  
Hydrogen Bond ◽  
Functional Groups ◽  
Molecular Spectroscopy ◽  
Spectroscopic Techniques ◽  
Hazardous Chemicals ◽  
Zeroth Order ◽  
Molecular Sensing ◽  
Molecular Binding ◽  
Selective Sorbent ◽  
Ir Spectroscopic

A zeroth order dendritic carbosilane structure, SiFA4H with four hexafluoroisopropanol (HFIP) functional groups attached via propyl ligand arms to a central silicon atom, has been developed as a model hydrogen-bond (HB) acid sorbent coating and candidate reference HB acid. The HB donor interaction, through the hydroxyl of the HFIP moiety, with a solute HB base can be monitored by observing the hydroxyl stretching frequency through measurements of SiFA4H FTIR spectra before and during vapor exposure. HFIP hydroxyl stretch shifts, upwards of 700 cm-1 have been observed depending on the HB base. For a range of HB bases, the resulting hydroxyl stretch shifts correlate directly with the solute HB basicity scale, “B”, developed by Abraham et al [1]. A variety of techniques exist to measure solute HB basicity, however, the applicability to examine HB bases delivered as vapors or gases and the simplicity of the measurements described herein, with a reusable reference HB acid sorbent coating and standard FTIR spectrophotometer techniques is attractive for some applications including those with hazardous chemicals. Moreover, as an extension of this work we propose employing SiFA4H or related sorbents as molecular sensing coatings, where the semi-selective sorbent is examined by various infrared (IR) spectroscopic techniques to monitor and identify hazardous chemicals, taking advantage of molecular binding phenomena which occur in the sorbent [2].

scholarly journals Synthesis characterization and antibacterial studies of 4-aminoantipyrine schiff’s bases

2017 ◽  
Vol 2 (01) ◽  
pp. 8-14 ◽  
Author(s):  
K Sunand ◽  
K Vinay Kumar ◽  
K Ashwini ◽  
P Suresh Kumar ◽  
S Vishnu ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Schiff Bases ◽  
Vital Role ◽  
Spectroscopic Techniques ◽  
Schiff’S Bases ◽  
Pharmacological Activities ◽  
Schiff's Bases ◽  
Ir Spectroscopic

Aim: To synthesize and evaluate 4-aminoantipyrine related schiff’s bases as antibacterial agents. Objective: To synthesize, purify, characterize and evaluate 4-aminoantipyrine. Method: Schiff bases derived from 4-aminoantipyrine play a vital role in biological and pharmacological activities. Knowing the importance of 4-aminoatipyrine schiff bases and their analogues wide varieties of bioactivities like analgesic, antiviral, antipyretic, anti-rheumatic, antimicrobial and anti-inflammatory activities have been widely studied. 4-aminoantipyrine compounds C1 (anisaldehyde), C2 (p-hydroxybenzaldehyde) and C3(vanillin) were prepared by condensation between 4-amino antipyrine and substituted aromatic benzaldehydes. The products were purified by recrystallization by using ethanol, characterized by IR spectroscopy. The N-H stretching in 4-aminoantipyrine is shown at 3430 cm-1 and -3325 cm-1. The -HC=N- stretching is observed in the range of 1508-1504 cm-1 The –OCH3 stretching is found at 1888 cm-1. 4-amino antipyrine related schiff’s bases evaluated their activity as antimicrobials in-vitro by spread plate method against E.coli. Schiff bases have potent antibacterial activity with gram negative bacteria E.coli. Results: Synthesis and characterization of a schiff bases derived from substituted benzaldehydes and 4-aminoantipyrine was evaluated and characterized with the IR spectroscopic techniques and schiff bases have shown potent antibacterial activity against E.Coli.

scholarly journals MINERALOGICAL CHARACTERIZATION STUDIES ON UNBURNT CERAMIC PRODUCT MADE FROM ROCK RESIDUE ADDITIVES BY FT-IR SPECTROSCOPIC TECHNIQUE

2013 ◽  
Vol 22 ◽  
pp. 62-70 ◽  
Author(s):  
R. VIJAYARAGAVAN ◽  
S. MULLAINATHAN ◽  
M. BALACHANDRAMOHAN ◽  
N. KRISHNAMOORTHY ◽  
S. NITHIYANANTHAM ◽  
...  
Keyword(s):  
Qualitative Analysis ◽  
Functional Groups ◽  
Spectroscopic Technique ◽  
Ceramic Product ◽  
Minor Constituent ◽  
Mineralogical Characterization ◽  
Ceramic Samples ◽  
Ft Ir ◽  
Characterization Studies ◽  
Ir Spectroscopic

The usability of waste rock (rock residue) powder as an additive material in ceramic samples was investigated. Qualitative analysis was carried out to determine the major and minor constituent minerals present in ceramic bodies made from rock residue powder by using FT-IR spectroscopic technique. Further, the representative ceramic bodies are analyzed by FT-IR technique to yield more information about the functional groups and also to estimate the order or disorder of kaolinite structure.

Steroid Compounds Isolation from Carthamus tinctorius Linn as Antimalarial

2021 ◽  
pp. 5297-5304
Author(s):  
Rini Hamsidi ◽  
Wahyuni Wahyuni ◽  
Adryan Fristiohady ◽  
Muhammad Hajrul Malaka ◽  
Idin Sahidin ◽  
...  
Keyword(s):  
Antimalarial Activity ◽  
Carthamus Tinctorius ◽  
Spectroscopic Techniques ◽  
1H And 13C Nmr ◽  
Marker Compound ◽  
Ic50 Value ◽  
Ft Ir ◽  
Ir Spectroscopic

Carthamus tinctorius Linn, also known as safflower, is a plant with the potential of being used in the production of antimalarial drugs. The purpose of this study was to isolate and identify the steroid compounds in the safflower and determine its antimalarial activity in vitro. The isolation process was conducted through extraction and chromatography methods. Then, the characterization of the isolated compounds was conducted through spectroscopic techniques which include Fourier Transform Infrared Spectroscopy (FT-IR), NMR 1-D (1H and 13C-NMR), and NMR 2-D (HMQC, HMBC, and H-H COZY) as well as comparing data with the existing literatures. In addition, the tests conducted were with variations of isolate concentrations (10, 1, 0.1, 0.01, and 0.001 μg/mL) against 3D7 strain of Plasmodium falciparum. Based on the FT-IR spectroscopic data, the steroid compounds isolated from safflowers might be stigmasterols. In addition, the isolates had -OH functional group in the region of 3431 cm-1, C-O in the region of 1053 cm-1, and Csp3-H in regions of 2960, 2934, and 2865 cm-1. The NMR 1-D data showed presence of 29 carbon atoms, while the protons were 48 in number. Furthermore, the IC50 value of the compound was 34.03 μg/mL with a percentage inhibition of 43.92% against the growth of P. falciparum. Therefore, it was classified as inactive agent in inhibiting the growth of malaria parasites, however, it could be used as a marker compound in C. tinctorius Linn extract.

scholarly journals Conversion of fisheries waste as magnetic hydroxyapatite bionanocomposite for the removal of heavy metals from groundwater

2017 ◽  
Vol 18 (4) ◽  
pp. 1406-1419
Author(s):  
F. Elmi ◽  
R. Chenarian Nakhaei ◽  
H. Alinezhad
Keyword(s):  
Heavy Metals ◽  
Freundlich Isotherm ◽  
Spectroscopic Techniques ◽  
Order Kinetic ◽  
Fish Scale ◽  
X Ray Diffraction ◽  
X Ray ◽  
Removal Of Heavy Metals ◽  
Order Kinetic Model ◽  
Ir Spectroscopic

Abstract This study is the first report of its type demonstrating the synthesis of mHAP on the basis of magnetic functionalization with nHAP, which were synthesized using Rutilus frisii kutum fish scale as a benign fishery waste by-product. The mHAP was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray diffraction (EDX), and Fourier transform infrared (FT-IR) spectroscopic techniques. The XRD pattern confirmed the formation of a single-phase nHAP without any extra steady phases. It was also found that the pseudo-second-order kinetic model gave a satisfactory fit to the experimental data (R2 = 0.99). The maximum removal percentages of Cu and Zn ions in optimal conditions (adsorbent dosage at 0.1 g, 30 min contact time at 25 ± 1 °C and pH = 5 ± 0.1) by mHAP were 97.1% and 93.8%, respectively. Results also demonstrated that mHAP could be recycled for up to five cycles in the case of copper and zinc. The Langmuir isotherm was proved to have a better correlation compared with that of the Freundlich isotherm. The thermodynamic parameters indicated that it was a spontaneously endothermic reaction. In conclusion, mHAP could be regarded as a powerful candidate for efficient biosorbent, capable of adsorbing heavy metals from aqueous solutions.

A strong asymmetric N–H–N hydrogen bond: Neutron diffraction and IR spectroscopic studies of 4‐aminopyridine hemiperchlorate

1980 ◽  
Vol 72 (11) ◽  
pp. 6117-6122 ◽  
Author(s):  
J. Rozière ◽  
Jack M. Williams ◽  
E. Grech ◽  
Z. Malarski ◽  
L. Sobcyzk
Keyword(s):  
Hydrogen Bond ◽  
Neutron Diffraction ◽  
Spectroscopic Studies ◽  
Ir Spectroscopic

scholarly journals Crystal Structure and Antitumor Activity of the Novel Zwitterionic Complex of tri-n-Butyltin(IV) with 2-Thiobarbituric Acid

2008 ◽  
Vol 2008 ◽  
pp. 1-5 ◽  
Author(s):  
Vasilios I. Balas ◽  
Sotiris K. Hadjikakou ◽  
Nick Hadjiliadis ◽  
Nikolaos Kourkoumelis ◽  
Mark E. Light ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Thiobarbituric Acid ◽  
Wistar Rat ◽  
In Vitro Cytotoxicity ◽  
Spectroscopic Techniques ◽  
X Ray Diffraction ◽  
Polycyclic Aromatic ◽  
Zwitterionic Complex ◽  
Ir Spectroscopic

A novel tri-n-butyl(IV) derivative of 2-thiobarbituric acid (HTBA) of formula[(n-Bu)3Sn(TBA)⋅H2O](1) has been synthesized and characterized by elemental analysis and119Sn-NMR and FT-IR spectroscopic techniques. The crystal structure of complex1has been determined by single crystal X-ray diffraction analysis at 120(2) K. The geometry around Sn(IV) is trigonal bipyramidal. Threen-butyl groups and one oxygen atom from a deprotonated 2-thiobarbituric ligand are bonded to the metal center. The geometry is completed with one oxygen from a water molecule. Compound1exhibits potent, in vitro, cytotoxicity against sarcoma cancer cells (mesenchymal tissue) from the Wistar rat, polycyclic aromatic hydrocarbons (PAH, benzo[a]pyrene) carcinogenesis. In addition, the inhibition caused by1, in the rate of lipoxygenase (LOX) catalyzed oxidation reaction of linoleic acid to hyperoxolinoleic acid, has been also kinetically and theoretically studied. The results are compared to that of cisplatin.

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