Demonstration of Molecular Sensing Using QCM Device Coated with Stimuli-sensitive Hydrogel

2012 ◽  
Vol 1498 ◽  
pp. 151-156 ◽  
Author(s):  
Yoshimi. Seida ◽  
Yuri Nakano ◽  
Yoshio Nakano
Keyword(s):  
Resonance Frequency ◽  
Quartz Crystal ◽  
Impedance Analysis ◽  
Stimuli Responsive ◽  
Polymer Hydrogel ◽  
Molecular Sensing ◽  
Resonance Behavior ◽  
Highly Sensitive ◽  
Stimuli Sensitive ◽  
Collapse Phase

ABSTRACTMolecular sensing using stimuli-responsive viscoelastic property of amphiphilic polymer hydrogel was demonstrated. Thermo-responsive poly(N-isopropylacrylamide); NIPA, hydrogel immobilizing bovine serum albumin (BSA) in its polymer chain was synthesized on the AT-cut QCM (Quartz crystal microbalance). The device was provided to the sensing of anti-BSA antibody. The resonance behavior of QCM in response to the adsorption of anti-BSA antibody on the hydrogel was observed based on both the resonance frequency and resistance of QCM with impedance analysis. The QCM device coated with the LCST polymer hydrogel revealed a characteristic resonance behavior in response to the adsorption of anti-BSA antibody in the collapse phase of gel at which the gel lost most of its hydrated water. The resonance frequency and resistance in the collapsed gel were highly sensitive and their changes in response to the target adsorption were much larger than in the swelling state of gel. The use of the device at the LCST of NIPA gel is ideal because the largest amplification of the adsorption signal is available along with the largest phase change of NIPA gel.

Smart Polymers and their Applications: A Review

2017 ◽  
Vol 8 (03) ◽  
Author(s):  
Gore S. A. ◽  
Gholve S. B. ◽  
Savalsure S. M. ◽  
Ghodake K. B. ◽  
Bhusnure O. G. ◽  
...  
Keyword(s):  
Oil Recovery ◽  
Water Soluble ◽  
Solution Temperature ◽  
Smart Polymers ◽  
Stimuli Responsive ◽  
Responsive Materials ◽  
Water Soluble Polymers ◽  
Commercial Applications ◽  
Stimuli Sensitive ◽  
External Stimuli

Smart polymers are materials that respond to small external stimuli. These are also referred as stimuli responsive materials or intelligent materials. Smart polymers that can exhibit stimuli-sensitive properties are becoming important in many commercial applications. These polymers can change shape, strength and pore size based on external factors such as temperature, pH and stress. The stimuli include salt, UV irradiation, temperature, pH, magnetic or electric field, ionic factors etc. Smart polymers are very promising applicants in drug delivery, tissue engineering, cell culture, gene carriers, textile engineering, oil recovery, radioactive wastage and protein purification. The study is focused on the entire features of smart polymers and their most recent and relevant applications. Water soluble polymers with tunable lower critical solution temperature (LCST) are of increasing interest for biological applications such as cell patterning, smart drug release, DNA sequencing etc.

Sensitive Mechanocontrolled Luminescence in Cross-Linked Polymer Films

2019 ◽  
Author(s):  
Ayumu Karimata ◽  
Pradnya Patil ◽  
Eugene Khaskin ◽  
Sébastien Lapointe ◽  
robert fayzullin ◽  
...  
Keyword(s):  
Mechanical Stress ◽  
Polymer Films ◽  
Soft Matter ◽  
Small Strain ◽  
Visual Methods ◽  
Photoluminescence Intensity ◽  
Stimuli Responsive ◽  
Responsive Materials ◽  
Highly Sensitive ◽  
Mechanical Stretching

Direct translation of mechanical force into changes in chemical behavior on a molecular level has important implication not only for the fundamental understanding of mechanochemical processes, but also for the development of new stimuli-responsive materials. In particular, detection of mechanical stress in polymers via non-destructive methods is important in order to prevent material failure and to study the mechanical properties of soft matter. Herein, we report that highly sensitive changes in photoluminescence intensity can be observed in response to the mechanical stretching of cross-linked polymer films when using stable, (pyridinophane)Cu-based dynamic mechanophores. Upon stretching, the luminescence intensity increases in a fast and reversible manner even at small strain (< 50%) and applied stress (< 0.1 MPa) values. Such sensitivity is unprecedented when compared to previously reported systems based on organic mechanophores. The system also allows for the detection of weak mechanical stress by spectroscopic measurements or by direct visual methods.<br>

UV Light Detection Using Resonance Frequency of Piezoelectric Quartz Crystal

2021 ◽  
pp. 1-5
Author(s):  
Surajit Das ◽  
Ashok Kumar ◽  
Ajay Kumar ◽  
Jitendra Singh ◽  
Rajan Jha ◽  
...  
Keyword(s):  
Resonance Frequency ◽  
Quartz Crystal ◽  
Uv Light ◽  
Light Detection ◽  
Piezoelectric Quartz ◽  
Piezoelectric Quartz Crystal

Miniaturized, highly sensitive single-chip multichannel quartz-crystal microbalance

2002 ◽  
Vol 81 (26) ◽  
pp. 5069-5071 ◽  
Author(s):  
Vu Ngoc Hung ◽  
Takashi Abe ◽  
Phan Ngoc Minh ◽  
Masayoshi Esashi
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Single Chip ◽  
Highly Sensitive

Viscoelastic Characterization of Electrochemically Prepared Conducting Polymer Films by Impedance Analysis at Quartz Crystal

2006 ◽  
Vol 153 (7) ◽  
pp. C455 ◽  
Author(s):  
A. Arnau ◽  
Y. Jimenez ◽  
R. Fernández ◽  
R. Torres ◽  
M. Otero ◽  
...  
Keyword(s):  
Conducting Polymer ◽  
Polymer Films ◽  
Quartz Crystal ◽  
Impedance Analysis ◽  
Conducting Polymer Films
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