Smart Materials with Dynamically Controllable Surfaces

MRS Bulletin ◽  
2005 ◽  
Vol 30 (3) ◽  
pp. 185-188 ◽  
Author(s):  
Joerg Lahann ◽  
Robert Langer

AbstractRecent progress in various biotechnology fields, such as microfluidics, tissue engineering, and cellular biology, has created a great demand for substrates that can undergo defined remodeling with time. As a result, the latest research on materials with dynamically controllable surface properties has led to a variety of novel smart surface designs.

Author(s):  
Timothy M. O’Shea ◽  
Alexander L. Wollenberg ◽  
Alexander M. Bernstein ◽  
Darren B. Sarte ◽  
Timothy J. Deming ◽  
...  

Author(s):  
Kun Zhang ◽  
Shuaimeng Guan ◽  
Longlong Cui ◽  
Jiankang Li ◽  
Jiaheng Liang ◽  
...  

2020 ◽  
Vol 11 (3) ◽  
pp. 47
Author(s):  
Floris Honig ◽  
Steven Vermeulen ◽  
Amir A. Zadpoor ◽  
Jan de Boer ◽  
Lidy E. Fratila-Apachitei

The ability to control the interactions between functional biomaterials and biological systems is of great importance for tissue engineering and regenerative medicine. However, the underlying mechanisms defining the interplay between biomaterial properties and the human body are complex. Therefore, a key challenge is to design biomaterials that mimic the in vivo microenvironment. Over millions of years, nature has produced a wide variety of biological materials optimised for distinct functions, ranging from the extracellular matrix (ECM) for structural and biochemical support of cells to the holy lotus with special wettability for self-cleaning effects. Many of these systems found in biology possess unique surface properties recognised to regulate cell behaviour. Integration of such natural surface properties in biomaterials can bring about novel cell responses in vitro and provide greater insights into the processes occurring at the cell-biomaterial interface. Using natural surfaces as templates for bioinspired design can stimulate progress in the field of regenerative medicine, tissue engineering and biomaterials science. This literature review aims to combine the state-of-the-art knowledge in natural and nature-inspired surfaces, with an emphasis on material properties known to affect cell behaviour.


Author(s):  
Pierre P.D. Kondiah ◽  
Yahya E. Choonara ◽  
Pariksha J. Kondiah ◽  
Thashree Marimuthu ◽  
Lisa C. du Toit ◽  
...  

2005 ◽  
Vol 288-289 ◽  
pp. 437-440 ◽  
Author(s):  
Guo Qiang Chen ◽  
Qiong Wu ◽  
Ya Wu Wang ◽  
Zhong Zheng

Poly(hydroxybutyrate-co-hydroxyhexanoate) (PHBHHx) has improved mechanical properties over the existing PHA and our results have shown that PHBHHx has better biocompatibility over polyhydroxybutyrate (PHB) and polylactic acid (PLA). Surface treatment with lipases dramatically changed the material surface properties and increased the biocompatibility of the PHBHHx. PHBHHx and its PHB blends had been used to make three dimensional structures and it has been found that cartilage, osteoblast, and fibroblasts all showed strong growth on the PHBHHx scaffolds. The growth was much better compared with PLA. The molecular studies also showed that mRNA encoding cartilages were strongly expressed when cartilage cells were grown on the PHBHHx. As PHBHHx has strong mechanical properties, easily processible and biodegradable, this material can be used to develop a new class of tissue engineering materials.


2003 ◽  
Author(s):  
Piotr Staszczuk ◽  
Dariusz Sternik

Molecules ◽  
2020 ◽  
Vol 25 (18) ◽  
pp. 4246 ◽  
Author(s):  
Yujie Chen ◽  
Chi Chen ◽  
Hafeez Ur Rehman ◽  
Xu Zheng ◽  
Hua Li ◽  
...  

Shape-memory materials are smart materials that can remember an original shape and return to their unique state from a deformed secondary shape in the presence of an appropriate stimulus. This property allows these materials to be used as shape-memory artificial muscles, which form a subclass of artificial muscles. The shape-memory artificial muscles are fabricated from shape-memory polymers (SMPs) by twist insertion, shape fixation via Tm or Tg, or by liquid crystal elastomers (LCEs). The prepared SMP artificial muscles can be used in a wide range of applications, from biomimetic and soft robotics to actuators, because they can be operated without sophisticated linkage design and can achieve complex final shapes. Recently, significant achievements have been made in fabrication, modelling, and manipulation of SMP-based artificial muscles. This paper presents a review of the recent progress in shape-memory polymer-based artificial muscles. Here we focus on the mechanisms of SMPs, applications of SMPs as artificial muscles, and the challenges they face concerning actuation. While shape-memory behavior has been demonstrated in several stimulated environments, our focus is on thermal-, photo-, and electrical-actuated SMP artificial muscles.


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