Nanotechnology and DNA Delivery

MRS Bulletin ◽  
2005 ◽  
Vol 30 (9) ◽  
pp. 654-658 ◽  
Author(s):  
Dan Luo

AbstractNonviral DNA delivery systems have great therapeutic and prophylactic potential, but their clinical utility has been limited by three major barriers: (1) inefficient uptake by the cell, (2) insufficient release of DNA within the cell, and (3) ineffective nuclear targeting and transport. Since the size of most cells is in the micrometer regime and the space inside a cell is extremely crowded, ideal DNA delivery systems must be in the nanometer range. Advancements in nanoscale science and nanotechnology have provided us with novel nanoparticles that may overcome all of these barriers, leading to higher-efficiency DNA delivery. This review article will focus on the recent developments in nanoscale DNA delivery systems that consist of chemical dendrimers, DNA dendrimers, nanospheres, nanolayers, nanorods, and nanotubes. The future of DNA delivery systems that interface with nanotechnology is also discussed.

2017 ◽  
Vol 10 (9) ◽  
pp. 1885-1910 ◽  
Author(s):  
Xiao Zhao ◽  
Hui Zhou ◽  
Vineet Singh Sikarwar ◽  
Ming Zhao ◽  
Ah-Hyung A. Park ◽  
...  

This review article focuses on the challenges and opportunities of biomass-based chemical looping technologies and explores fundamentals, recent developments and future perspectives.


2021 ◽  
Vol 06 ◽  
Author(s):  
Ayekpam Chandralekha Devi ◽  
G. K. Hamsavi ◽  
Simran Sahota ◽  
Rochak Mittal ◽  
Hrishikesh A. Tavanandi ◽  
...  

Abstract: Algae (both micro and macro) have gained huge attention in the recent past for their high commercial value products. They are the source of various biomolecules of commercial applications ranging from nutraceuticals to fuels. Phycobiliproteins are one such high value low volume compounds which are mainly obtained from micro and macro algae. In order to tap the bioresource, a significant amount of work has been carried out for large scale production of algal biomass. However, work on downstream processing aspects of phycobiliproteins (PBPs) from algae is scarce, especially in case of macroalgae. There are several difficulties in cell wall disruption of both micro and macro algae because of their cell wall structure and compositions. At the same time, there are several challenges in the purification of phycobiliproteins. The current review article focuses on the recent developments in downstream processing of phycobiliproteins (mainly phycocyanins and phycoerythrins) from micro and macroalgae. The current status, the recent advancements and potential technologies (that are under development) are summarised in this review article besides providing future directions for the present research area.


1968 ◽  
Vol 5 (1) ◽  
pp. 83-94 ◽  
Author(s):  
Ronald E. Frank ◽  
Paul E. Green

Recent developments in numerical taxonomy appear to show applicability for many classification problems in marketing. This review article describes some of the approaches to numerical classification and presents illustrative marketing applications. Current limitations of the procedures are also discussed.


Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1986
Author(s):  
Xiaoming Ma ◽  
Sanjun Zhi ◽  
Wei Zhang

Multicomponent reactions (MCRs) have inherent advantages in pot, atom, and step economy (PASE). This important green synthetic approach has gained increasing attention due to high efficiency, minimal waste, saving resources, and straightforward procedures. Presented in this review article are the recent development on 5-compoment reactions (5CRs) of the following six types: (I) five different molecules A + B + C + D + E; pseudo-5CRs including (II) 2A + B + C + D, (III) 2A + 2B + C, (IV) 3A + B + C, (V) 3A + 2B, and (VI) 4A + B. 5CRs with more than five-reaction centers are also included.


2021 ◽  
Vol 11 (9) ◽  
pp. 4242
Author(s):  
Manggar Arum Aristri ◽  
Muhammad Adly Rahandi Lubis ◽  
Sumit Manohar Yadav ◽  
Petar Antov ◽  
Antonios N. Papadopoulos ◽  
...  

This review article aims to summarize the potential of using renewable natural resources, such as lignin and tannin, in the preparation of NIPUs for wood adhesives. Polyurethanes (PUs) are extremely versatile polymeric materials, which have been widely used in numerous applications, e.g., packaging, footwear, construction, the automotive industry, the lighting industry, insulation panels, bedding, furniture, metallurgy, sealants, coatings, foams, and wood adhesives. The isocyanate-based PUs exhibit strong adhesion properties, excellent flexibility, and durability, but they lack renewability. Therefore, this study focused on the development of non-isocyanate polyurethane lignin and tannin resins for wood adhesives. PUs are commercially synthesized using polyols and polyisocyanates. Isocyanates are toxic, costly, and not renewable; thus, a search of suitable alternatives in the synthesis of polyurethane resins is needed. The reaction with diamine compounds could result in NIPUs based on lignin and tannin. The research on bio-based components for PU synthesis confirmed that they have good characteristics as an alternative for the petroleum-based adhesives. The advantages of improved strength, low curing temperatures, shorter pressing times, and isocyanate-free properties were demonstrated by lignin- and tannin-based NIPUs. The elimination of isocyanate, associated with environmental and human health hazards, NIPU synthesis, and its properties and applications, including wood adhesives, are reported comprehensively in this paper. The future perspectives of NIPUs’ production and application were also outlined.


Author(s):  
Teena Sheethal Dsouza ◽  
Mithra N. Hegde ◽  
Kelvin Peter Pais

AbstractThe sudden outbreak of the coronavirus disease 2019 pandemic has compelled universities worldwide to implement strategies for resuming academic courses by transferring some courses to a virtual modality. e-Learning has provided an excellent platform for education during this crisis. This review article discusses the various aspects of e-learning process that have to be considered before implementation, and the strengths and flaws of online education during this pandemic. It also sheds light on the necessary actions required to enhance the efficiency of e-learning in the future.


1978 ◽  
Vol 5 (3) ◽  
pp. 334-339
Author(s):  
Brian E. Sullivan

The transit system serving Greater Vancouver has high ridership and a high rate of growth. Using as a base the well-designed, well-patronized trolleybus grid in the City of Vancouver, an inter-connected suburban bus network has been created, with radial, cross-radial, and local routes meeting on a timed connection basis at suburban shopping centres and other foci. Planners' thoughts for the future include greater emphasis on the micro and macro aspects of land use and relations to transit; the use of capital intensive modes for heavy trunk routes; and the use of various forms of para-transit for low-density and certain feeder applications.


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