Innovations in Biomaterials: Achievements and Opportunities

MRS Bulletin ◽  
2005 ◽  
Vol 30 (7) ◽  
pp. 540-545 ◽  
Author(s):  
Rebecca M. Bergman

AbstractThis article is an edited transcript based on a presentation given by Rebecca M. Bergman (Medtronic Inc.) as part of Symposium X—Frontiers of Materials Research on November 30, 2004, at the Materials Research Society Fall Meeting in Boston. Materials innovations have been at the heart of many important advances in implantable medical devices. Miniaturization, improved durability and longevity, enhanced biocompatibility, and controlled delivery are several areas where materials innovations have been important in advancing medical products and therapies. The demands on materials used in the physiological environment are stringent and include requirements related to materials properties as well as safety, quality, and reliability. Looking ahead, materials will undoubtedly continue to be an enabling technology for future innovations in medicine, including novel therapies such as tissue engineering, cell therapy, and gene therapy.

2018 ◽  
Vol 11 (1) ◽  
pp. 127-146 ◽  
Author(s):  
Hatice Ceylan Koydemir ◽  
Aydogan Ozcan

Mobile health technologies offer great promise for reducing healthcare costs and improving patient care. Wearable and implantable technologies are contributing to a transformation in the mobile health era in terms of improving healthcare and health outcomes and providing real-time guidance on improved health management and tracking. In this article, we review the biomedical applications of wearable and implantable medical devices and sensors, ranging from monitoring to prevention of diseases, as well as the materials used in the fabrication of these devices and the standards for wireless medical devices and mobile applications. We conclude by discussing some of the technical challenges in wearable and implantable technology and possible solutions for overcoming these difficulties.


MRS Bulletin ◽  
2006 ◽  
Vol 31 (6) ◽  
pp. 477-485 ◽  
Author(s):  
Robert Langer

AbstractThe following article is an edited transcript based on the Von Hippel Award presentation by Robert Langer of the Massachusetts Institute of Technology on November 30, 2005, at the Materials Research Society Fall Meeting in Boston. Langer was honored with MRS's highest award for his “pioneering accomplishments in the science and application of biomaterials in drug delivery and tissue engineering, particularly in inventing the use of materials for protein and DNA delivery, and for his achievements in interdisciplinary research which have generated new medical products, created new fields of biomaterials science, and inspired research programs throughout the world.”


Author(s):  
Gen Satoh ◽  
Caian Qiu ◽  
Syed Naveed ◽  
Y. Lawrence Yao

The continued advancement of implantable medical devices has resulted in the need to join a variety of dissimilar, biocompatible metal pairs to enable selective use of their unique properties. Typical materials used in implantable medical devices include stainless steel (SS), titanium, platinum (Pt), as well as shape memory materials such as NiTi. Joining these dissimilar metal pairs, however, often results in excessive formation of brittle intermetallics, which significantly reduce the strength of the joints. The use of filler materials to combat the formation of intermetallics, however, results in reduced biocompatibility. Autogenous laser brazing is a novel process that is able to form thin, localized joints between dissimilar metal pairs without filler materials. In this study, the formation of autogenous laser brazed joints between NiTi and SS wires is investigated through experiments and numerical simulations. The strength, composition, microstructure, and phase formation of the resultant joints are investigated as a function of processing parameters and thermal, fluid flow, and phase prediction simulations are used to aid in understanding the joint formation mechanism.


MRS Bulletin ◽  
2003 ◽  
Vol 28 (7) ◽  
pp. 506-510
Author(s):  
Michelle Aubert

AbstractThe following article is based on a presentation given as part of Symposium X—Frontiers of Materials Research on December 4, 2002, at the 2002 Materials Research Society Fall Meeting. The cinema is just over 100 years old. From the beginning of motion pictures in the mid-1890s, the materials used for films have been at the heart of cinema technology. The material first used was cellulose nitrate film—unrivaled in its mechanical, physical, and aesthetic qualities, and also dangerously flammable. In the 1950s, cellulose nitrate was replaced, for safety reasons, by cellulose triacetate. Today, polyester film is widely used; nevertheless, the fact remains that the majority of the world's film heritage exists on two main material formats, cellulose nitrate and cellulose triacetate, both of which decay over time. Film archivists are engaged in a race to save historic film footage from being lost forever. Digital technology, now widely used in cinema, does not resolve the issue of the long-term preservation of films because digital formats are still evolving. This article discusses the materials used in motion-picture technology over the years, the mechanisms active in film decomposition, and international efforts to preserve and restore historic films.


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