Selective detection of folic acid in the midst of other biomolecules using water-soluble AgInS2 quantum dots

2019 ◽  
Vol 9 (4) ◽  
pp. 1306-1310 ◽  
Author(s):  
Bambesiwe M.M. May ◽  
Sundararajan Parani ◽  
Jose Varghese Rajendran ◽  
Oluwatobi S. Oluwafemi
Keyword(s):  
Quantum Dots ◽  
Folic Acid ◽  
Water Soluble ◽  
Selective Detection ◽  
Image Position

Abstract

Cell viability assessments of green synthesized water-soluble AgInS2/ZnS core/shell quantum dots against different cancer cell lines

2019 ◽  
Vol 34 (24) ◽  
pp. 4037-4044 ◽  
Author(s):  
Oluwatobi S. Oluwafemi ◽  
Bambesiwe M.M. May ◽  
Sundararajan Parani ◽  
Jose Varghese Rajendran
Keyword(s):  
Quantum Dots ◽  
Cell Viability ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Water Soluble ◽  
Core Shell ◽  
Image Position

Abstract

Detection of ascorbic acid and folic acid based on water-soluble CuInS2 quantum dots

The Analyst ◽  
2012 ◽  
Vol 137 (19) ◽  
pp. 4598 ◽  
Author(s):  
Siyu Liu ◽  
Junjie Hu ◽  
Xingguang Su
Keyword(s):  
Quantum Dots ◽  
Ascorbic Acid ◽  
Folic Acid ◽  
Water Soluble ◽  
Cuins2 Quantum Dots

The Synthesis of the Folate Acid Quantum Dots and Its Endocytosis in the Hepatoma Cells Mediated by the Folate Receptor

2019 ◽  
Vol 9 (6) ◽  
pp. 770-777
Author(s):  
Xiao-Li Zhu ◽  
Jing-Cheng Tang ◽  
Bing-Jiu Xu
Keyword(s):  
Quantum Dots ◽  
Folic Acid ◽  
Hepg2 Cells ◽  
Folate Receptor ◽  
Synthetic Medium ◽  
Water Soluble ◽  
Mercaptoacetic Acid ◽  
Green Method ◽  
Cds Qds ◽  
Hepg2 Cell Lines

Objectives: To synthesize folate acid conjugated quantum dots (QDs) by a simple and green method and explore endocytosis of the QD-folic acid conjugates (FA-QDs) into hepG2 cells. Methods: CdS QDs were prepared using stearic acid as synthetic medium, and were conjugated with mercaptoacetic acid (MAA) to be water-soluble. Then folic acid moiety was coupled to the surface of the QDs using EDC (1-ethyl-3-(3-dimethylamino propyl)carbodiimide) as a coupling agent. The CdS QDs and FA-QDs were characterized by X-ray spectroscopy (XRD), transmission electron microscopy (TEM), spectro fluorimetry and infrared spectroscopy. Endocytosis of the FA-QDs into hepG2 cells was observed by confocal microscopy and TEM. Results: TEM shows that the CdS QDs and FA-QDs were spherical in shape and had a diameter of 10 nm. Fluorescence spectrum of the QDs also shows their narrow size distribution. Confocal microscopic and TEM results show that FA-QDs were successfully internalized into the hepG2 cells. In addition, confocal results show that when the cells were first be saturated with excess free FA, the endocytosis of the FA-QDs became less, and CdS QDs that were not conjugated with FA were not able to be internalized into the hepG2 cells. Conclusions: The FA-QDs can be synthesized by a simple and green method and be used to successfully target tumor cells: hepG2 cell lines, which was probably mediated by the FA receptor.

A green one-pot synthesis of nitrogen and sulfur co-doped carbon quantum dots for sensitive and selective detection of cephalexin

2017 ◽  
Vol 95 (6) ◽  
pp. 641-648 ◽  
Author(s):  
Farhad Akhgari ◽  
Naser Samadi ◽  
Khalil Farhadi ◽  
Mehrdad Akhgari
Keyword(s):  
Quantum Dots ◽  
Carbon Dots ◽  
Limit Of Detection ◽  
Carbon Quantum Dots ◽  
Water Soluble ◽  
Soluble Nitrogen ◽  
Selective Detection ◽  
Photoluminescence Intensity ◽  
Doped Carbon Dots ◽  
Co Doped

The article reports a simple, economic, and green method for preparing water-soluble, nitrogen and sulfur co-doped carbon quantum dots via a one-step hydrothermal method. Pomegranate juice served as the carbon source, and the L-cysteine provided nitrogen and sulfur. Co-doped carbon dots were characterized by X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), and Fourier transform infrared (FTIR) spectroscopy techniques. The co-doped carbon dots served as fluorescent probes for sensitive and selective detection of cephalexin. Briefly, the co-doped carbon dot systems showed quenching of photoluminescence intensity in the presence of cephalexin. The decrease of fluorescence intensity made it possible to analyze cephalexin with satisfactory detection limits and linear ranges. The Sterne–Volmer plot showed a linear relationship (R2 = 0.998) between F0/F and the concentration of cephalexin over the range from 0.3 to 10 μmol L−1. The limit of detection (LOD) was estimated to be 1 × 10−7 mol L−1 (at a signal to noise ratio of 3). To validate the applicability, the described method was successfully applied for the detection of cephalexin in human urine and raw milk samples.

High selectivity in water soluble MoS2 quantum dots for sensing nitro explosives

2016 ◽  
Vol 4 (26) ◽  
pp. 6321-6326 ◽  
Author(s):  
Dhrubaa Haldar ◽  
Diptiman Dinda ◽  
Shyamal Kumar Saha
Keyword(s):  
Quantum Dots ◽  
High Selectivity ◽  
Water Soluble ◽  
Selective Detection ◽  
Amine Functionalized ◽  
Nitro Explosives ◽  
Aromatic Nitro

Rapid and highly selective detection of Aromatic Nitro explosive Trinitrophenol by amine functionalized MoS2 QDs.

scholarly journals CdTe Quantum Dots Modified with Cysteamine: A New Efficient Nanosensor for the Determination of Folic Acid

Sensors ◽  
2019 ◽  
Vol 19 (20) ◽  
pp. 4548 ◽  
Author(s):  
Doris E. Ramírez-Herrera ◽  
Ana Patricia Reyes-Cruzaley ◽  
Giselle Dominguez ◽  
Francisco Paraguay-Delgado ◽  
Antonio Tirado-Guízar ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Folic Acid ◽  
Fluorescence Quenching ◽  
Low Cost ◽  
Water Soluble ◽  
Cdte Quantum Dots ◽  
Photoluminescence Intensity ◽  
Beverage Samples ◽  
Cdte Qds

In this paper, we report the synthesis, characterization, and application of a new fluorescent nanosensor based on water-soluble CdTe quantum dots (QDs) coated with cysteamine (CA) for the determination of folic acid (FA). CdTe/CA QDs were characterized by high-resolution transmission electron microscopy, the zeta potential, and Fourier-transform infrared (FT-IR), UV-visible, and fluorescence spectroscopy. CdTe QDs coated with mercaptopropionic acid (MPA) and glutathione (GSH) were prepared for comparison purposes. The effect of FA on the photoluminescence intensity of the three thiol-capped QDs at pH 8 was studied. Only CdTe/CA QDs showed a notable fluorescence quenching in the presence of FA. Then, a nanosensor based on the fluorescence quenching of the CdTe QDs at pH 8 was explored. Under optimum conditions, the calibration curve showed a linear fluorescence quenching response in a concentration range of FA from 0.16 to 16.4 μM (R2 = 0.9944), with a detection limit of 0.048 μM. A probable mechanism of fluorescence quenching was proposed. The nanosensor showed good selectivity over other possible interferences. This method has been applied for FA quantification in orange beverage samples with excellent results (recoveries from 98.3 to 103.9%). The good selectivity, sensitivity, low cost, and rapidity make CdTe /CA QDs a suitable nanosensor for FA determination.

Water-soluble plasmonic nanosensors with synthetic receptors for label-free detection of folic acid

2015 ◽  
Vol 51 (47) ◽  
pp. 9678-9681 ◽  
Author(s):  
Randa Ahmad ◽  
Nordin Félidj ◽  
Leïla Boubekeur-Lecaque ◽  
Stéphanie Lau-Truong ◽  
Sarra Gam-Derouich ◽  
...  
Keyword(s):  
Folic Acid ◽  
Molecularly Imprinted Polymers ◽  
Water Soluble ◽  
Selective Detection ◽  
Label Free ◽  
Molecularly Imprinted ◽  
Label Free Detection ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Gold nanorods were coated by molecularly imprinted polymers for the selective detection of folic acid using surface-enhanced Raman scattering.

Sign in / Sign up

Export Citation Format

Share Document