Evaluation of vascular function by modern non-invasive methods

2012 ◽  
Vol 153 (48) ◽  
pp. 1887-1895 ◽  
Author(s):  
Attila Nemes ◽  
Tamás Forster
Keyword(s):  
Early Detection ◽  
Coronary Flow Reserve ◽  
Vascular Injury ◽  
Vascular Function ◽  
Coronary Flow ◽  
Morphological Changes ◽  
Non Invasive ◽  
Flow Reserve ◽  
Clinical Methods ◽  
Myocardial Flow

Vascular functional alterations frequently precede morphological changes and, therefore, their recognition may theoretically improve early detection of vascular injury. The aim of this review is to demonstrate recently available non-invasive clinical methods including vascular stiffness examinations, flow-mediated vasodilatation, coronary flow reserve and myocardial flow reserve measurements. Orv. Hetil., 2012, 153, 1887–1895.

P940Effects of IQOS smoking on vascular function, coronary flow reserve, myocardial deformation and myocardial work index during one month of use

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
I Ikonomidis ◽  
K Katogiannis ◽  
K Kourea ◽  
G Kostelli ◽  
D Vlastos ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Coronary Flow Reserve ◽  
Vascular Function ◽  
Coronary Flow ◽  
Smoking Status ◽  
Myocardial Strain ◽  
Chronic Phase ◽  
Myocardial Deformation ◽  
Flow Reserve ◽  
Work Index

Abstract Background IQOS smoking (heat-no burn smoke product) is proposed to reduce harm compared to conventional smoking. We examined its effects on vascular function, myocardial deformation and ventricular arterial coupling. Methods Thirty-seven current smokers (mean age 48±5 years, >20 cigarettes /day) without cardiovascular disease and 20 healthy subjects with similar age sex and risk factors participated in the study. All subjects were instructed to smoke only IQOS for one month. Measurements were performed at baseline and 1 month after smoking IQOS. we measured a) the aortic PWV (PWV) and central aortic systole blood pressure (SBPc) by Complior; b) the exhaled CO level (parts per million-ppm) as a smoking status marker; and c) brachial systolic (SBP)and diastolic (DBP) blood pressure and heart rate (HR) a) flow mediated dilation (FMD) of the brachial artery b) coronary flow reserve (CFR) after adenosine infusion by Doppler echocardiography and c) global longitundinal strain (GLS) peak twisting and untwisting velocity and myocardial work index derived by pressure –myocardial strain loops by speckle tracking imaging PWV to GLS ratio was also used as a marker of ventricular arterial coupling Results At baseline exhaled CO, PWV, SBPc, FMD, PWV/GLS ratio, myocardial work index and peak untwisting velocity were higher and CFR was lower in smokers compared to controls (14.9±7 vs. 4.2±1 ppm, p<0.001, 8.7±1.4 vs 10.0±1.6 m/s, p<0.05; 118±16 vs 110±7 mmHg p<0.001, 6.9±2 vs 9.5±2% p<0.001, −0.61±0.21 vs. −0.45±0.11 m/sec%, p<0.001, 1926±284 vs 1826±300 mmHg% p=0.04, −122±36 vs −95±25 deg/sec, p=0.02, 2.5±0.9 vs. 3.1±0.8 p=0.001 respectively). In the chronic phase we observed a significant improvement of FMD, CFR, GLS, PWV/GLS, myocardial work index and peak untwisting velocity compared to baseline (12±2% vs. 6.9±2%, p=0.03; 3.2±0.6 vs. 2.5±0.9 p=0.001; −19.3±2.2% vs. −21.1±2.8%, p=0.001; −0.61±0.21 vs. −0.47±0.12 m/sec% p=0.03; 1926±284 vs 1830±343 mmHg% p=0.03, −122±36 vs −105±25 deg/sec, p=0.03, respectively) in parallel with reduction of the exhaled CO (14.9±7 vs. 6±4.9 ppm, p<0.001). HR remained unchanged throughout the study and there was a borderline reduction of central aortic systolic blood pressure (118±16 vs. 114±19 mmHg, p=0.048). Conclusions Replacement of conventional cigarettes with IQOS results in improved LV longitundinal myocardial deformation, LV untwisting and reduced LV myocardial work index possibly linked to the concomitant improvement of aortic elasticity, endothelial and coronary microcirculatory function and ventricular-arterial coupling within 1 month.

scholarly journals CORRELATION BETWEEN FRAILTY AND NON-INVASIVE CORONARY FLOW RESERVE: A CROSS SECTIONAL STUDY

2017 ◽  
Vol 69 (11) ◽  
pp. 2541
Author(s):  
Amjad M. Ahmed ◽  
Ihab Sulaiman ◽  
Mousa Alfaris ◽  
Dalia Ahmed ◽  
Ahmed Aljizeeri ◽  
...  
Keyword(s):  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Non Invasive ◽  
Flow Reserve

scholarly journals 152 Determinants of non invasive coronary flow reserve in severe aortic stenosis

2012 ◽  
Vol 4 (1) ◽  
pp. 48-49
Author(s):  
Patrick Meimoun ◽  
Anne Laure Germain ◽  
Frederic Elmkies ◽  
Tahar Benali ◽  
Jacques Boulanger ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
Severe Aortic Stenosis ◽  
Non Invasive ◽  
Flow Reserve
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