The “gray zone” in fine-needle aspiration cytology of the organized mammography screening. Cytohistological correlation

2011 ◽  
Vol 152 (8) ◽  
pp. 292-295
Author(s):  
Mihály Bak ◽  
Éva Konyár ◽  
Ferenc Schneider ◽  
Mária Bidlek ◽  
Éva Szabó ◽  
...  

The National Public Health Program has established the organized mammography screening in Hungary. The aim of this study was to conduct an audit of “gray zone” smears of the organized mammography screening in comparison with histopathological diagnoses. Methods: Cytology results were rated to C3 atypia probably benign and C4 suspicious of malignancy. Results: 1361 women had aspiration cytology performed from a total of 47,718 mammography non-negative lesions. 105 (7.8%) were diagnosed as C3, whereas 78 (5.7) as C4. Of the 105 patients with C3 diagnosis 61 (58%) patients underwent surgical biopsy. Histology proved malignancy in 20 (32.8%) cases, and benign lesion in 41 (67.2%) cases. All (100%) of the 78 patients with C4 diagnosis had open biopsies; 69 (88.4%) cases were histologically malignant and 9 (11.6%) cases were benign lesions. Conclusion: The auditing results of fine needle aspiration cytology of “gray zone” in organized mammography screening meet the proposed threshold values. Authors conclude that the “gray zone” category in breast cytology is useful and of value if used judiciously. Orv. Hetil., 2011, 152, 292–295.

2010 ◽  
Vol 151 (32) ◽  
pp. 1295-1298 ◽  
Author(s):  
Mihály Bak ◽  
Éva Konyár ◽  
Ferenc Schneider ◽  
Mária Bidlek ◽  
Éva Szabó ◽  
...  

A Nemzeti Népegészségügyi Program az emlőrák szervezett szűrését biztosítja. Célkitűzés: Dolgozatunk célja a szervezett emlőrákszűrés során a mammográfia, illetve ultrahangvizsgálatokkal nem negatív elváltozások aspirációs citológiai diagnózisainak minőségbiztosítása. Módszer: A citológiai diagnózisokat 5 kategóriába (C1, C2, C3, C4, C5) soroltuk. A citológiai módszer diagnosztikus érzékenységét a szövettani eredményekhez viszonyítva elemeztük. Eredmények: Összesen 47718 mammográfiás és ultrahangvizsgálattal a kóros emlőelváltozásokból 1361 citológiai vizsgálatot végeztünk. A leggyakoribb diagnózis benignus (805 eset, 59, 1%), illetve carcinoma (187 eset, 13,7%) volt. Az összesített pozitív, negatív esetek számításánál a szenzitivitás 91%, a specificitás 88%, a pozitív prediktív érték 96,6%, a negatív prediktív érték 71%-nak (p<0,001) bizonyult. Megbeszélés: Megállapítottuk, hogy tanulmányunkban az emlőelváltozások vékonytű-aspirációs citológiai vizsgálatainak minőségbiztosítási eredményei megfelelnek, és több tekintetben jobbak a nemzetközileg elvárt követelményeknél.


CytoJournal ◽  
2021 ◽  
Vol 18 ◽  
pp. 23
Author(s):  
Shruti Gupta ◽  
Pranab Dey

Fine-needle aspiration cytology (FNAC) is an excellent technique for rapid diagnosis due to its speed, accuracy, and cost-effectiveness. However, there are many gray-zone areas in cytology that needs attention. These lesions in the aspiration cytology can be overcome by applying the selective use of the series of tests. This review discusses the diagnostic challenges in the gray-zone areas in FNAC. It emphasizes the use of selective ancillary techniques to solve the problems in this area.


1997 ◽  
Vol 38 (5) ◽  
pp. 815-820 ◽  
Author(s):  
S. Ciatto ◽  
M. Rosselli Del Turco ◽  
D. Ambrogetti ◽  
P. Bravetti ◽  
S. Catarzi ◽  
...  

Purpose: To evaluate the contribution of guided fine-needle aspiration cytology in reducing unnecessary biopsies of benign solid nonpalpable breast lesions with low suspicion of malignancy at mammography. Material and Methods: An evaluation was made of a consecutive series of 2444 solid nonpalpable breast lesions detected by mammography and undergoing guided (sonography or stereotaxy) fine-needle aspiration cytology. Surgical biopsy was made in the presence of strong suspicion of malignancy at mammography and/or of abnormal cytology. Results: The sensitivity was 96.7% and the specificity 77.7% (average follow-up 2.77 years). False-negative/inadequate cytology associated with low suspicion of malignancy at mammography resulted in a diagnostic delay in 27 cancer cases (invasive 20, intraductal 7). On the other hand, cytology led to surgical biopsy in 53 cancer cases which might not otherwise have been biopsied because of low radiological suspicion of cancer. Surgical biopsy of all cases, to avoid diagnostic delays, would have increased the benign biopsy rate by a factor of 4.5, with a rise in the benign: malignant biopsy ratio from 0.44:1 to 1.93:1. Conclusion: Stereotaxy- or ultrasound-guided fine-needle aspiration cytology of nonpalpable mammographic abnormalities can achieve a sharp reduction in unnecessary benign biopsies in cases of low suspicion of malignancy at mammography.


2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Neha Meena ◽  
Pooja Arora

<p class="Body"><span lang="EN-US">Giant cell tumour of the tendon sheath (GCTTS) is a slow-growing, usually painless benign lesion of soft tissues<span style="font-size: 8.33333px;">.</span> We report the case of a 38-year-old male with a painless, slowly enlarging swelling on right thumb in order to highlight the role of fine-needle aspiration cytology (FNAC) in diagnosing GCTTS.</span></p>


2020 ◽  
Vol 7 (12) ◽  
pp. 3951
Author(s):  
Y. Ananta Lakshmi ◽  
K. V. Narasimha Reddy

Background: The solitary node in thyroid is a palpably discrete swelling within an apparently normal thyroid gland. It is usually a benign lesion but from clinical standpoint the possibility of neoplastic disease is of major concern for surgeon and patient. AS there is variability in the conclusion of various authors and there is no work about clinicopathology of solitary nodules of thyroid in our region. Present study has been designed to evaluate the epidemiology, fine needle aspiration cytology and incidence of malignancy in solitary nodule.Methods: As per exclusion and inclusion criteria 80 patients with solitary nodule of thyroid were included in this study. Various data like age, sex, family history, duration of nodule, site and size of nodule were recorded. Thyroid function test, fine needle aspiration cytology and ultrasonographic finding were recorded from case record.Results: Out of all histopathological finding of nodules follicular adenoma was most common followed by multinodular goitre (25%) and Adenomatous goitre (7.5%). Carcinoma was present in (17.5 %) and thyroiditis is 7.5% patients.Conclusions: Most of the patients were Euthyroid and benign condition was more common than malignancy. Follicular adenoma was most common among benign lesion and papillary carcinoma was more common neoplasm. Most of the patients required hemithyroidectomy.


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