Effect of enteral feeding on gallbladder function in dogs

2012 ◽  
Vol 60 (2) ◽  
pp. 211-222 ◽  
Author(s):  
Roland Psáder ◽  
Ágnes Sterczer ◽  
Kinga Pápa ◽  
Andrea Harnos ◽  
Viktória Szilvási ◽  
...  
Keyword(s):  
Enteral Feeding ◽  
Feeding Tube ◽  
Fundamental Principle ◽  
Gallbladder Motility ◽  
Gallbladder Emptying ◽  
Beagle Dogs ◽  
Ultrasound Guided ◽  
Gallbladder Contraction ◽  
Gallbladder Function ◽  
Duodenojejunal Junction

Nutritional support in critically ill patients is a fundamental principle of patient care. Little is known about gallbladder motility during the interdigestive phase and in response to enteral feeding. The objective of this study was to investigate the effect of enteral feeding on gallbladder function in dogs. The cholagogue meal (Lipofundin infusion) was applied in four anatomical positions (jejunum, duodenojejunal junction, descending duodenum, stomach) in five healthy Beagle dogs. Gallbladder volume (GBV) was monitored by ultrasonography. Lipofundin infusion given through the feeding tube caused a maximal gallbladder contraction of 9.2% (range 3.7–13.9%) in the jejunum, 16.5% (9.1–22.1%) at the duodenojejunal junction and 26.3% (22.8–29.5%) in the descending duodenum. When the cholagogue meal was given through the mouth, it caused a mean 33.8% (28.6–46.5%) maximum gallbladder contraction in the same animals. In conclusion, we can establish that the ultrasound-guided gallbladder emptying method proved to be a useful technique for monitoring the cholagogue effect of Lipofundin meal applied in different anatomical positions of the intestine. The deeper the position of application, the smaller and shorter gallbladder contraction was evoked.

Cholagogue-induced gallbladder emptying in the diagnosis of canine biliary obstruction

2012 ◽  
Vol 60 (2) ◽  
pp. 199-209 ◽  
Author(s):  
Ágnes Sterczer ◽  
Jenő Reiczigel ◽  
Roland Psáder ◽  
Kinga Pápa ◽  
Károly Vörös ◽  
...  
Keyword(s):  
Magnesium Sulphate ◽  
Biliary Obstruction ◽  
Surgical Intervention ◽  
Gallbladder Emptying ◽  
Beagle Dogs ◽  
Ultrasound Guided ◽  
Gallbladder Contraction ◽  
Maximum Reduction ◽  
Hepatobiliary Diseases ◽  
Stimulation Of

The efficacy of ultrasound-guided cholagogue-induced gallbladder emptying for differentiating obstructive from non-obstructive hepatobiliary diseases was studied in icteric dogs. In 7 healthy Beagle dogs, Lipofundin 20% infusion (2 ml/kg orally) evoked a vigorous gallbladder contraction of 44.2% (range: 35.3–57.6%) and proved to be a useful, well-tolerable meal for routine use. In 24 icteric dogs, gallbladder contraction was evoked by different cholagogues: the maximum reduction in gallbladder volume (%) for the three non-obstructive icteric dogs was 43.9% (range, 39.0–46.5%). The average gallbladder contraction of the 21 dogs with biliary obstruction was less than 5%. In conclusion, the stimulation of gallbladder contraction with orally applied magnesium sulphate (MgSO4) or Lipofundin can be well demonstrated by ultrasound in dogs. The examination of cholagogue-induced gallbladder emptying is a valuable technique in icteric patients to indicate surgical intervention.

Group I: Choosing the Appropriate Method of Placement of an Enteral Feeding Tube in the High-Risk Population

1997 ◽  
Vol 12 (1) ◽  
pp. S54-S55 ◽  
Author(s):  
Timothy O. Lipman ◽  
Oliver W. Cass ◽  
Chia Sing Ho ◽  
Patrick J. Kearns ◽  
Scott A. Shikora
Keyword(s):  
High Risk ◽  
Enteral Feeding ◽  
Feeding Tube ◽  
High Risk Population ◽  
Risk Population ◽  
Enteral Feeding Tube ◽  
Group I ◽  
Method Of Placement

scholarly journals Manipulations of Oral Medications in Paediatric Neurology and Oncology Care at a Swedish University Hospital: Health Professionals’ Attitudes and Sources of Information

Pharmaceutics ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1676
Author(s):  
Rania Kader ◽  
Gunnar Liminga ◽  
Gustaf Ljungman ◽  
Mattias Paulsson
Keyword(s):  
Enteral Feeding ◽  
Product Information ◽  
Feeding Tube ◽  
Paediatric Oncology ◽  
Working Environment ◽  
University Hospital ◽  
Hazardous Substances ◽  
Oral Dosage ◽  
Sources Of Information ◽  
Oral Medications

Oral administration of medications to children requires age-appropriate dosage forms and strengths. In this study, we: (i) assessed the extent of oral dosage form manipulations, (ii) documented how it is carried out, and (iii) examined the attitudes and sources of information regarding the handling from healthcare professionals. Prospective reviews of electronic records, ward observations, and clinician surveys were performed at a paediatric neurology ward and a paediatric oncology ward in Sweden during April to May of 2018. Approximately 15% of oral medications were manipulated for the studied patient group (median age 12.9 years in oncology, 5.8 years in neurology) with approximately 30% of the patients having an enteral feeding tube. Manipulations were performed both to obtain an appropriate dose from, for example, a fraction of the original tablet or to obtain a powder that could be used to prepare a slurry for administration through enteral feeding tubes. Risks identified were related to patient safety such as cross contamination, suboptimal absorption/pharmacokinetics and inaccurate dose. When examining the working environment of nurses, we observed safe handling of hazardous substances but the nurses occasionally experienced stress and a fear of making mistakes due to absence of information. Paediatricians experienced a lack of time to search for proper information on manipulations. As a step towards improving safety in paediatric medication, we suggest the introduction of clinical pharmacists into the team and further evaluating the possibilities of using more ready-to-administer medications with necessary product information and pharmacovigilance support.

Motor cycles with phase III in antrum are associated with high motilin levels and prolonged gallbladder emptying

1993 ◽  
Vol 264 (4) ◽  
pp. G596-G600 ◽  
Author(s):  
M. F. Stolk ◽  
K. J. van Erpecum ◽  
A. J. Smout ◽  
L. M. Akkermans ◽  
J. B. Jansen ◽  
...  
Keyword(s):  
Bile Acid ◽  
Cycle Length ◽  
Phase Iii ◽  
Gallbladder Motility ◽  
Gallbladder Emptying ◽  
Motor Complex ◽  
Group 2 ◽  
Relationship Of ◽  
The Relationship ◽  
Group 1

We examined the relationship of interdigestive gallbladder emptying with the different phases of the migrating motor complex (MMC) and with plasma levels of cholecystokinin (CCK) and motilin. In 10 volunteers 20 cycles of the MMC were recorded. In 11 cycles phase III occurred in antrum and duodenum (group 1). In nine cycles phase III was observed only in duodenum (group 2). In group 1 gallbladder emptying started at 30% of total cycle length and continued until the end of the cycle. Maximal gallbladder emptying was 33.3 +/- 3.3% (SE). In group 2 gallbladder emptying also started at 30% of total cycle length but ended at 60%. Maximal gallbladder emptying in this group was 24.3 +/- 3.1% (P < 0.05). Motilin levels were higher in group 1 than in group 2 during phase IIB (240.1 +/- 28.5 and 142.1 +/- 30.9 pg/ml, respectively, P < 0.05) and during phase III (210.8 +/- 24.3 and 93.5 +/- 12.5 pg/ml, respectively, P < 0.05). We conclude that: 1) phase III activities starting in the antrum are preceded by greater and prolonged gallbladder emptying, higher motilin levels, and higher intraduodenal bile acid concentrations than phase III activities starting in the duodenum and 2) no relationship between interdigestive gallbladder motility and CCK levels could be demonstrated.

scholarly journals Evaluation of the profile of drug therapy administered through enteral feeding tube in a general hospital in Rio de Janeiro

2011 ◽  
Vol 47 (2) ◽  
pp. 331-337 ◽  
Author(s):  
Mario Jorge Sobreira da Silva ◽  
Carlos Eduardo Meireles Cava ◽  
Patrícia Kaiser Pedroso ◽  
Débora Omena Futuro
Keyword(s):  
Drug Therapy ◽  
Enteral Feeding ◽  
Rio De Janeiro ◽  
Clinical Status ◽  
Nutritional Therapy ◽  
Feeding Tube ◽  
Oral Feeding ◽  
Enteral Feeding Tube ◽  
Effective Use ◽  
Recommended Guidelines

Enteral nutrition (EN) is the method of choice for patients that cannot adequately receive oral feeding despite good gastrointestinal tract condition. Enteral diets may be administered through tube or ostomy placed in the stomach, duodenum or jejunum. The administration of drugs via enteral feeding tube (EFT) is a common practice in hospitals due to patient clinical status, and requires special attention from professionals involved in this process. This study entailed an analysis of the profile of drug therapy through EFT based on evaluation of medical prescriptions of the Medical Clinic of the Hospital dos Servidores do Estado (HSE) of Rio de Janeiro sent to the Pharmacy Service between January and June 2007, according to standard protocols in place. Prescription of drugs via EFT outside recommended guidelines was observed, besides potential drug-nutrient incompatibilities associated with this practice. These results point to the need for improvement of enteral route access and the adoption of measures to promote safe and effective use of drugs and nutritional therapy.

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