scholarly journals Cornealis elváltozások Wilson-kórban

2019 ◽  
Vol 160 (14) ◽  
pp. 555-557 ◽  
Author(s):  
Zoltán Sohajda ◽  
Márta Hódos ◽  
László Módis
Keyword(s):  
Metabolic Disease ◽  
Optical Coherence Tomography ◽  
Autosomal Recessive ◽  
Wilson’S Disease ◽  
Anterior Segment ◽  
Corneal Topography ◽  
Specular Microscopy ◽  
Optical Coherence ◽  
Examination Methods ◽  
Corneal Disorder

Abstract: Wilson’s disease is an autosomal recessive hereditary metabolic disease with a pathological accumulation of copper in tissues. This study presents the case of a family, where two females and one male from among six siblings had this disease. While in the case of the two women only the liver was affected, the young man presented with both psychiatric and ophthalmic disorders. Modern examination methods (anterior segment optical coherence tomography, corneal topography, endothelial specular microscopy) were used to gather data on the corneal disorder that manifested with the classic Kayser–Fleischer ring. We underline the importance of ophthalmological checkup which may help to diagnose this disease. Orv Hetil. 2019; 160(14): 555–557.

Diagnostic Accuracy of Anterior Segment Optical Coherence Tomography Pachymetry Mapping and Detection for Early Keratoconus using Corneal Topography as Gold Standard

2021 ◽  
Vol 15 (10) ◽  
pp. 2796-2799
Author(s):  
Hafiz Huzaifa Akhlaq ◽  
Syed Ahmad Hassan Waqas Subzwari ◽  
Fatima Akbar Shah ◽  
Rafih Razzaq Wattoo ◽  
Umair Tariq Mirza ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Diagnostic Accuracy ◽  
Predictive Value ◽  
Gold Standard ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Corneal Topography ◽  
Optical Coherence ◽  
Cutoff Value ◽  
Department Of Ophthalmology

Background: Optical coherence tomography (OCT) derived pachymetry mapping has potential in diagnosis of early and advancing keratoconus. The OCT corneal pachymetry map–based logistic regression formula and the keratoconus risk scoring system has been proven to provide very accurate results in keratoconus identification. In keratoconus screening these techniques might be helpful. Objectives: To ascertain the diagnostic accuracy of anterior segment optical coherence tomographic corneal pachymetry to diagnose the cases the cases of early keratoconus by using corneal topography as a high standard with which other techniques of these kinds are compared. Study Design: Cross-sectional (validation) study. Duration: One year from July 01, 2019 to June 30, 2020. Settings: Department of Ophthalmology, Allied Hospital/DHQ Hospital, Faisalabad Pakistan. Methodology: A total of 195 patients having asymmetrical astigmatism (>1 diopter), 12-40 years of age of both genders were included. Patients with corneal ulcer and corneal opacity were excluded. After complete examination corneal topography and anterior segment optical coherence tomography was performed. Tomographic minimum central corneal thickness was recorded and assessed for cutoff value, if exceeding cutoff value patient was diagnosed with the early keratoconus. Results: In OCT pachymetry positive patients, 103 (True Positive) had early keratoconus and 05 (False Positive) had no early keratoconus on corneal topography. Among 87, OCT pachymetry negative patients, 04 (False Negative) had early keratoconus on corneal topography whereas 83 (True Negative) had no early keratoconus on corneal topography (p=0.0001). Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of anterior segment optical coherence tomographic corneal pachymetry to diagnose the cases of early keratoconus in the suspected individuals by using corneal topography as gold standard was 96.26%, 94.32%, 95.37%, 95.40% and 95.38% respectively. Conclusion: This study concluded that diagnostic accuracy of anterior segment optical coherence tomographic corneal pachymetry to find out the cases of early keratoconus is very high. Keywords: Optical coherence tomographic corneal pachymetry, Keratoconus, Sensitivity

scholarly journals Comparison of Four Methods for Corneal Thickness Measurement

2013 ◽  
Vol 6 (1) ◽  
pp. 37-42
Author(s):  
Teodora L. Marinova ◽  
Vesela Ivancheva ◽  
Svilena S. Peeva ◽  
Christina N. Grupcheva
Keyword(s):  
Optical Coherence Tomography ◽  
Laser Scanning ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Laser Scanning Confocal Microscopy ◽  
Thickness Measurement ◽  
Specular Microscopy ◽  
Optical Coherence ◽  
Cornea Thickness

Summary The aim of the study was to evaluate the thickness of the normal cornea in order to establish correlation between four methods of measuring including: ultrasound pachymetry (USP), anterior segment optical coherence tomography (ASOCT), non-contact tono/pachymetry (TONOPACHY) and laser-scanning confocal microscopy (LSCM). The study was based on evaluating repeatability and comparability of four different methods formeasuring the corneal thickness. Non contact specular microscopy was first performed on all 27 patients (aged between 20 and 24 years) to evaluate corneal characteristics and confirm the absence of pathological changes. Each participant was examined by USP, ASOCT and TONOPACHY, and 13 eyes of 10 persons were also examined by LSCM. The values of average central corneal thickness measured by USP, ASOCT, TONOPACHY and LSCM were 532.20±4.5 pm, 553.33±12.1 pm, were 548.20±5.62 pm and 573.33±7.22 pm, respectively. There was a high correlation between the instruments. The mean differences for central corneal thickness measurements were 41.43±1.67 pm between USP and LSCM, 20.43±2.4 pm between USP and ASOCT, and 22.1 ±3.88 pm between USB and TONOPACHY. Anterior segment optical coherence tomography overestimated corneal thickness as compared with that measured by USP, which is believed to be a gold standard. Anterior segment optical coherence tomography had better agreement with USP, as compared with LSCM. However, the results of measured cornea thickness by TONOPACHY were very close to cornea thickness measured by ASOCT.

Pediatric Free-floating Anterior Chamber Cyst of the Iris Pigment Epithelium

2018 ◽  
Vol 1 ◽  
pp. 3
Author(s):  
Joshua S Agranat ◽  
Yoshihiro Yonekawa
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Chamber ◽  
Incidental Finding ◽  
Pigment Epithelium ◽  
Anterior Segment ◽  
Ultrasound Biomicroscopy ◽  
Optical Coherence ◽  
Visual Axis ◽  
Associated Malignancy ◽  
Anatomic Locations

Iris pigment epithelial (IPE) cysts are a subset of iris cysts that arise from the IPE. They are spontaneously erupting epithelial-lined cavities that are found in various anatomic locations of the iris, including the iris pupillary margin, midzone, periphery, and free floating in the vitreous or anterior chamber. We report the case of an asymptomatic 13-year-old boy with an incidental finding of a dislodged anterior chamber cyst diagnosed on routine examination. Modern multimodal image analysis of the cyst including anterior segment optical coherence tomography and ultrasound biomicroscopy (UBM) was utilized to characterize the microstructural anatomy of the lesion. The patient was managed conservatively without complications. Cysts of the IPE typically do not affect vision or ocular health and can be monitored and observed after ascertaining no associated malignancy. Initial diagnostic investigation can include UBM and anterior segment optical coherence tomography. Intervention should be reserved only for cases where the cyst growth leads to obstruction of the visual axis and/or other secondary complications.

Sign in / Sign up

Export Citation Format

Share Document