scholarly journals Az endokrin orbitopathia differenciáldiagnosztikája

2016 ◽  
Vol 157 (8) ◽  
pp. 310-315
Author(s):  
Annamária Erdei ◽  
Zita Steiber ◽  
Annamária Gazdag ◽  
Miklós Bodor ◽  
Eszter Berta ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Literature Review ◽  
Graves Disease ◽  
Endocrine Orbitopathy ◽  
Common Cause ◽  
Graves Orbitopathy ◽  
Eye Symptoms

Graves’ orbitopathy is the extrathyroidal manifestation of Graves’ disease, which is the most common cause of exophthalmos. As eye symptoms usually coincide with the development of thyrotoxicosis, the diagnosis of the disease is rarely difficult. The aim of the authors was to summarize the differential diagnosis of Graves’ orbitopathy based on literature review and presentation of their own four problematic cases on this topic. They conclude that symptoms similar to endocrine orbitopathy are present in other disorders. Endocrinologists need to be aware of these other conditions to avoid treatment failures. Orv. Hetil., 2016, 157(8), 310–315.

scholarly journals Description of Colonoscopy and Histopathology of Chronic Diarrhea Causes in Non-Neoplasm: Literature Review

2021 ◽  
Vol 22 (1) ◽  
pp. 52-59
Author(s):  
Afifah Sakdyyah ◽  
Muhammad Begawan Bestari ◽  
Sri Suryanti
Keyword(s):  
Differential Diagnosis ◽  
Risk Factor ◽  
Literature Review ◽  
Chronic Diarrhea ◽  
Microscopic Colitis ◽  
Differential Diagnoses ◽  
Definite Diagnosis ◽  
Infectious Colitis ◽  
Common Cause

Chronic diarrhea is a diarrhea symptom which persists for ≥ 4 weeks as a symptom of a disease. Chronic diarrhea is a symptom which often becomes the patient’s cause to be referred to gastroenterology. In general, the prevalence of chronic diarrhea is approximated to be 5% in each populations, but there are obstacles in diagnosing the cause of chronic diarrhea, due to many differential diagnoses of the cause of chronic diarrhea. The cause of chronic diarrhea could be neoplasm and non-neoplasm. In several studies, through results of colonoscopy and histopathology, it was found that the most common cause of chronic diarrhea was non-neoplasm, including IBD, microscopic colitis as a risk factor, and infectious colitis as a differential diagnosis. Each of those diseases has similar symptoms, but different pathological description. Through descriptions of colonoscopy and histopathology of chronic diarrhea causes, it is possible to differentiate each non-neoplasm causes of chronic diarrhea. It could facilitate in finding the differences among the causes of chronic diarrhea especially in non-neoplasm cases, therefore possibly establishing a definite diagnosis. 

Novel treatment opportunities in Graves’ orbitopathy

2014 ◽  
Vol 155 (33) ◽  
pp. 1295-1300
Author(s):  
Annamária Erdei ◽  
Annamária Gazdag ◽  
Miklós Bodor ◽  
Eszter Berta ◽  
Mónika Katkó ◽  
...  
Keyword(s):  
Clinical Experience ◽  
Clinical Course ◽  
Treatment Protocol ◽  
Treatment Modalities ◽  
Graves Disease ◽  
Novel Treatment ◽  
Graves Orbitopathy ◽  
Cd20 Antibody ◽  
Anti Cd20 ◽  
Novel Therapeutic

Graves’ orbitopathy is the most common extrathyroidal manifestation of Graves’ disease. Up to now, curative treatment modalities for the most severe sight-threatening cases have not been developed. Here the authors summarize the treatment protocol of Graves’ orbitopathy and review novel therapeutic options. They review the literature on this topic and present their own clinical experience. The authors point out that anti-CD20 antibody could positively influence the clinical course of Graves’ orbitopathy. Selenium is efficient in mild cases. Further prospective investigations are warranted. Orv. Hetil., 2014, 155(33), 1295–1300.

scholarly journals Cerebral fat embolization with paroxysmal sympathetic hyperactivity syndrome and septic shock at high altitude: a case report and literature review

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Min Li ◽  
Gang Zhu ◽  
Hao Guo ◽  
Shun Nan Ge ◽  
Guo Dong Gao ◽  
...  
Keyword(s):  
Septic Shock ◽  
Differential Diagnosis ◽  
Case Report ◽  
Literature Review ◽  
High Altitude ◽  
Fat Embolism ◽  
Neurological Rehabilitation ◽  
Case Presentation ◽  
Sympathetic Hyperactivity ◽  
Paroxysmal Sympathetic Hyperactivity

AbstractBackgroundCerebral fat embolism (CFE) syndrome at high altitude was rare complicated with paroxysmal sympathetic hyperactivity (PSH) syndrome and septic shock. It is a challenge to differential diagnosis and treatment at high altitude.Case presentationThis case presents a CFE with PSH and septic shock of a 23-year-old man occurred at high altitude of 3800 m above sea level, transferred by airplane successfully and cured in the department of neurosurgery, Xi’an Tangdu Hospital.ConclusionsIt is key that CFE with PSH can be rapid diagnosed and treatment bundles of septic shock should be initiated as soon as possible. Early neurological rehabilitation played an important role for good outcome.

Clinical relevance of T lymphocyte subsets in pediatric Graves’ disease

2020 ◽  
Vol 33 (11) ◽  
pp. 1425-1430
Author(s):  
Ting Chen ◽  
Linqi Chen ◽  
Haojie Song ◽  
Xiuli Chen ◽  
Rongrong Xie ◽  
...  
Keyword(s):  
T Cell ◽  
Peripheral Blood ◽  
Clinical Characteristics ◽  
Hepatic Dysfunction ◽  
Lymphocyte Subsets ◽  
Cytotoxic T Cell ◽  
Graves Disease ◽  
T Lymphocyte Subsets ◽  
Graves Orbitopathy ◽  
Normal Alanine Aminotransferase

AbstractObjectivesGraves’ disease (GD) is an autoimmune disease involving intimate response of both T cells and B cells. Immunophenotyping of peripheral blood lymphocyte subsets in GD children with different clinical characteristics can provide further information of the pathogenesis of GD.MethodsWe studied the lymphocyte subsets in peripheral blood of 141 children with GD. We repeatedly divided the patients into two groups in accordance with different clinical characteristics (abnormal or normal alanine aminotransferase (ALT) levels, the presence or absence of Graves’ orbitopathy (GO), and the presence or absence of hematuria. Then we compared the lymphocyte subsets measurements between two paired groups.ResultsWe found that serum ALT levels correlated positively with CD3+CD8+ T cell percentages in children with GD. Moreover, we detected higher percentages of CD3−CD19+ cells and higher ratio of CD4/CD8 in patients with GO. However, no correlation was found between GO status and lymphocyte subsets after excluding confounding effect of TRAb. No difference of lymphocyte subset percentages was found between groups with or without hematuria.ConclusionsSerum ALT levels correlate positively with cytotoxic T cell percentages in the peripheral blood of children with GD. The cytotoxic T cell may play a role in the pathogenesis of hepatic dysfunction in children with GD.

Case Report and Literature Review of Nodular Hidradenoma, a Rare Adnexal Tumor That Mimics Breast Carcinoma, in a 20-Year-Old Woman

2019 ◽  
Vol 50 (3) ◽  
pp. 320-325
Author(s):  
Vanya Jaitly ◽  
Richard Jahan-Tigh ◽  
Tatiana Belousova ◽  
Hui Zhu ◽  
Robert Brown ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Breast Carcinoma ◽  
Literature Review ◽  
Sweat Glands ◽  
Rare Presentation ◽  
Adnexal Tumor ◽  
Nodular Hidradenoma ◽  
Growing Mass ◽  
Uncommon Tumor

Abstract Nodular hidradenoma is an uncommon cutaneous adnexal tumor arising from sweat glands. In the skin, it usually presents as a solitary dermal nodule; excision is curative in most cases. In rare instances, it may present as a breast mass and can mimic breast carcinoma clinically and radiologically, causing diagnostic dilemmas for the treating physician and pathologist. Herein, we discuss a case of nodular hidradenoma in a 20-year-old Hispanic woman as a rapidly growing mass in the breast that mimicked breast carcinoma. We discuss the rare presentation of this uncommon tumor and the differential diagnosis of this entity, as well as the results of our literature review on the topic.

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