scholarly journals Comparison of erythromycin and oxytetracycline for the treatment of ovine footrot

2001 ◽  
Vol 49 (2) ◽  
pp. 131-139 ◽  
Author(s):  
S. Píriz ◽  
T. Pobel ◽  
Ruth Jiménez ◽  
E. M. Mateos ◽  
P. Martín-Palomino ◽  
...  
Keyword(s):  
Success Rate ◽  
Intramuscular Injection ◽  
The Other ◽  
Penicillin G ◽  
Bacterial Isolates ◽  
Microbiological Study ◽  
Dichelobacter Nodosus

A microbiological study of 25 cases of ovine footrot was performed. Cultures belonging to Dichelobacter nodosus were isolated in 48% of the sampled animals. The sensitivity of the 99 strict anaerobic bacterial isolates to 5 antibiotics (penicillin G, amoxycillin, spiramycin, erythromycin and oxytetracycline) was studied. The percentage of resistant cultures was in all cases higher than 30%. The efficacy of erythromycin and oxytetracycline in the treatment of ovine footrot was studied. To conduct this test, an intramuscular injection was applied, of one antimicrobial or the other, at the beginning of the treatment. The tolerance of animals to the antimicrobials, the success rate of treatment and the severity of lameness were evaluated. The percentage of animals cured within 15 days was around 75%. In contrast, only 44% improvement was achieved in the lameness. No differences were found between the two antimicrobials in the above indices.

Cytochemical Studies of Cell Wall Biosynthesis in Staphylococcus Aureus

1972 ◽  
Vol 30 ◽  
pp. 328-329
Author(s):  
Masaatsu Koike ◽  
Koichi Nakashima ◽  
Kyoko Iida
Keyword(s):  
Staphylococcus Aureus ◽  
Periodate Oxidation ◽  
Early Time ◽  
The Other ◽  
Penicillin G ◽  
Cell Wall Biosynthesis ◽  
Septal Wall ◽  
Peptidoglycan Biosynthesis ◽  
Gram Positive Bacteria ◽  
Cross Linkage

Penicillin exerts the activity to inhibit the peptide cross linkage between each polysaccharide backbone at the final stage of wall-peptidoglycan biosynthesis of bacteria. Morphologically, alterations of the septal wall and mesosome in gram-positive bacteria, which were occurred in early time after treatment with penicillin, have been observed. In this experiment, these alterations were cytochemically investigated by means of silver-methenamine staining after periodate oxidation, which is applied for detection of localization of wall mucopolysaccharide.Staphylococcus aureus strain 209P treated with 100 u/ml of penicillin G was divided into two aliquotes. One was fixed by Kellenberger-Ryter's OSO4 fixative at 30, 60 and 120 min after addition of the antibiotic, dehydrated through alcohol series, and embedded in Epon 812 (Specimen A). The other was fixed by 21 glutaraldehyde, dehydrated through glycolmethacrylate series and embedded in glycolmethacrylate mixture, according to Bernhard's method (Specimen B).

Tissue Damage Caused by the Intramuscular Injection of Long-Acting Penicillin

PEDIATRICS ◽  
1985 ◽  
Vol 75 (4) ◽  
pp. 741-744
Author(s):  
Harry Schanzer ◽  
Julius H. Jacobson
Keyword(s):  
New Zealand ◽  
Femoral Artery ◽  
Normal Saline ◽  
Tissue Damage ◽  
Intramuscular Injection ◽  
Penicillin G ◽  
Left Femoral Artery ◽  
New Zealand White Rabbits ◽  
Long Acting ◽  
The Right

In order to elucidate whether tissue damage produced on occasion by intramuscular injection of longacting penicillin is due to accidental intra-arterial injection or vasospasm, two types of experiments were carried out in rabbits. In the first set of experiments, six New Zealand White rabbits were given intra-arterial injections of 0.4 mL of a mixture containing 300,000 U of penicillin G benzathine and 300,000 units of penicillin procaine per milliliter (Bicillin C-R) into the left femoral artery and 0.4 mL of normal saline into the right femoral artery as autocontrol. In a second set of experiments, 0.4 mL of the same penicillin preparation was injected in the space surrounding the left femoral artery in five New Zealand rabbits, and 0.4 mL of normal saline was injected in a similar fashion around the right femotal artery as control. The legs of the rabbits that received the intra-arterial injection of penicillin invariably developed ischemic manifestations. None of the legs of rabbits given intra-arterial injections of normal saline had pathologic manifestations. None of the rabbits that received the periarterial penicillin preparation or normal saline developed abnormalities. These results strongly suggest that the tissue damage produced by penicillin is secondary to the intra-arterial administration of the drug.

STUDIES OF PENICILLIN IN PEDIATRICS

PEDIATRICS ◽  
1950 ◽  
Vol 5 (4) ◽  
pp. 664-671
Author(s):  
B. M. KAGAN ◽  
M. NIERENBERG ◽  
D. GOLDBERG ◽  
A. MILZER
Keyword(s):  
Intramuscular Injection ◽  
Room Temperature ◽  
Serum Levels ◽  
Sesame Oil ◽  
Peanut Oil ◽  
Penicillin G ◽  
Procaine Penicillin ◽  
Pertinent Data ◽  
Significant Difference ◽  
Pediatric Use

Table I summarizes most of the pertinent data in this report on the serum penicillin concentrations 12 and 24 hours after intramuscular injection of K penicillin G in peanut oil and beeswax, which is fluid at room temperature, and of three different procaine penicillin preparations. These three preparations are procaine penicillin G in sesame oil, procaine penicillin G in peanut oil with 2% aluminum monostearate, and procaine penicillin G in water with Na-carboxymethylcellulose. When they were given in a dosage of 8000 u./lb. to infants and children, weighing between 4.5 and 18.0 kg., there was no statistically significant difference in the serum levels obtained. A dosage schedule for these preparations is suggested for pediatric use. The aqueous preparation offers some advantages which are discussed. Experiences are reported which emphasize the necessity of avoiding intravenous administration of all these preparations.

scholarly journals SOSIALISASI TEMPE SEBAGAI MAKANAN ORGANIK DAN SEHAT KEPADA IBU RUMAH TANGGA DI KOTA TANGERANG SELATAN

2018 ◽  
Vol 2 (2) ◽  
pp. 92-103
Author(s):  
Anastasi Tatik Hartanti ◽  
Yasinta Ratna Esti Wulandari ◽  
Rory Anthony Hutagalung ◽  
Tati Barus
Keyword(s):  
Success Rate ◽  
Community Service ◽  
Food Processing ◽  
Healthy Food ◽  
The Other ◽  
Survey Method ◽  
Community Knowledge ◽  
Survey Results ◽  
Strongly Agree

Tempeh is a traditional Indonesian food that has many advantages as food and the process of making it is quite simple. However, the community knowledge about tempeh and the skills to produce healthy tempeh are still low. This community service aimed to increase the knowledge about tempeh and to improve the skills of its manufacturers in making healthy and good quality tempeh. The activities were carried out for mothers living in Villa Dago Tol complex, Ciputat, South Tangerang 15414, by using the methods of counseling, demonstration, and mentoring. Monitoring was conducted to measure the success rate of participants in producing healthy tempeh. The level of community knowledge about tempeh was evaluated through survey method. The results of counseling, demonstration, and mentoring succeeded in improving the participant skills as seen from the participants' success in following the healthy tempeh-making procedure. The results were also reinforced by the results of monitoring where all participants managed to create healthy tempeh. Survey results showed participants’ increasing knowledge of healthy tempeh and motivation in producing healthy tempeh. Assessment of participants showed good results, especially in improving knowledge (73% stated strongly agree and the rest agree). The ability of the facilitators in delivering the material was also considered good by the participants (92% stated strongly agree and the rest agree). As a follow-up, the participants suggested that the training be extended to the other communities and the training also include a variety of topics such as the manufacturing of tofu, healthy food processing, sewing, and many others.

Isolation and Molecular Characterization of Klebsiella And Enterobacter Species Recovered in Sunflower Seed Agar from Cases Resembling Respiratory Cryptococcosis

2021 ◽  
Author(s):  
Felix Emele Emele ◽  
Kehinde Caleb Daramola ◽  
Arthur Ebelenna Anyabolu
Keyword(s):  
Sunflower Seed ◽  
The Other ◽  
Klebsiella Pneumonia ◽  
Bacterial Isolates ◽  
Viral Etiology ◽  
Enterobacter Species ◽  
Cryptococcus Species ◽  
Enterobacter Ludwigii ◽  
Pcr Techniques

Respiratory cryptococcosis caused by Cryptococcus species can present with symptoms indistinguishable from bacterial or viral etiology. Cryptococcus species produce typical colonial features on Sunflower Seed Agar (SSA), which aids in rapid diagnoses of cryptococcosis. In studying respiratory cryptococcosis, we observed bacterial growths on SSA that resembled Cryptococcus species in colonial characteristics. This study aimed at identifying and characterizing those bacterial isolates for documentation. Sputum samples were collected from 201 patients with symptoms suggestive of respiratory cryptococcosis. The samples were inoculated onto SSA, incubated at 37oC for two weeks. Suspected colonies were further evaluated. Of the samples, none yielded Cryptococcus species, although a total of twenty Cryptococcus-resembling bacterial colonies were encountered and isolated. Eight of the isolates could not amplify by PCR techniques. The other twelve were identified as follows: Klebsiella pneumonia (8 or 67%), Klebsiella ozaneae (3 or 25%), and Enterobacter ludwigii (1 or 8%). All isolates were susceptible to Ertapenem, Meropenem, and Fosfomycin but resistant to ampicillin. Results show that Klebsiella and Enterobacter pneumonia-like illnesses can be misidentified as cryptococcosis using SSA.  Reliance on microscopic rather than macroscopic, colonial features on SSA will prevent misdiagnosis.

Rheumatic Fever Article Questioned

PEDIATRICS ◽  
1984 ◽  
Vol 74 (6) ◽  
pp. 1133-1134
Author(s):  
SYLVIA P. GRIFFITHS
Keyword(s):  
Rheumatic Fever ◽  
Intramuscular Injection ◽  
Group A Streptococcus ◽  
Penicillin G ◽  
Benzathine Penicillin ◽  
Benzathine Penicillin G ◽  
Group A

To the Editor.— The suggestion of Nordin1 that there may be a need to re-evaluate the current recommended prophylaxis for children with rheumatic fever is valid, particularly if carefully planned and controlled studies could be carried out. However, the author's contention that "It has been assumed that the levels of penicillin [following monthly intramuscular injection of 1.2 million units of benzathine penicillin G] are adequate to prevent reinfection with group A streptococcus, and hence to prevent recurrences of rheumatic fever" has always been qualified by others.

Impact of Social Media Readiness on Social Media Usage and Competitive Advantage

2019 ◽  
pp. 246-267
Author(s):  
Apoorv Durga ◽  
M. L. Singla
Keyword(s):  
Social Media ◽  
Competitive Advantage ◽  
Success Rate ◽  
Failure Rate ◽  
Media Use ◽  
The Other ◽  
Value Chains ◽  
Media Usage ◽  
Effective Implementation ◽  
Use Of Social Media

Usage of social media within organizations' value chains has been increasing rapidly. There are several benefits and savings projected due to usage of social media. As a result, there is also a lot of hype that is typical of any new web phenomenon. On the other hand, saner voices are cautioning against excessive hype and point to high failure rate of social media initiatives. Lack of best practices or frameworks and incomplete understanding of how to make best use of social media are some of the reasons cited for this high failure of social media initiatives. In addition, there are several other aspects related to governance, people, and processes that need to be addressed to improve success rate of these initiatives. Therefore, effective implementation of a social media initiative includes addressing all those aspects that relate to governance, people, and processes. The authors use a construct, “Social Media Readiness,” that encapsulates these aspects. This chapter summarizes research that shows how readiness can impact social media use.

A Practical Evaluation of the Delvotest P Multi Plate Test in Screening Raw Milk for Antibiotics

1986 ◽  
Vol 49 (11) ◽  
pp. 868-870 ◽  
Author(s):  
LYSE LAROCQUE ◽  
G. A. NEVILLE
Keyword(s):  
Bacillus Subtilis ◽  
Staphylococcus Epidermidis ◽  
Raw Milk ◽  
The Other ◽  
Penicillin G ◽  
Antibiotic Residues ◽  
Plate Test ◽  
Milk Samples ◽  
Practical Evaluation ◽  
Bacillus Subtilis Atcc

The Delvotest P Multi plate test was evaluated by screening 100 milk samples for total antibiotic residues (penicillin G, streptomycin and neomycin). The samples were taken in conjunction with an antibiotic depletion study in milk derived from six cows treated with a multiple antibiotic, intramammary infusion product. Within the limits of sensitivity of the Delvotest, only penicillin G persisted in milk samples taken beyond 60 h, whereas in some samples, the other antibiotics appeared to be depleted as early as 48 h. More sensitive tests, however, detected neomycin (Staphylococcus epidermidis, ATCC 12228) in 50% of samples taken at 60 h and streptomycin (Bacillus subtilis, ATCC 6633) at 14.5 d after discontinuation of infusion.

scholarly journals Microdilution Antimicrobial Susceptibilities of Selected Gram-Negative Veterinary Bacterial Isolates

1993 ◽  
Vol 5 (4) ◽  
pp. 541-547 ◽  
Author(s):  
G. E. Burrows ◽  
R. J. Morton ◽  
W. H. Fales
Keyword(s):  
Escherichia Coli ◽  
Bimodal Distribution ◽  
Pasteurella Haemolytica ◽  
Penicillin G ◽  
Animal Disease ◽  
Bacterial Isolates ◽  
Diagnostic Laboratory ◽  
Gram Negative ◽  
Minimal Inhibitory Concentrations ◽  
Different Tissues

Gram-negative bacterial isolates (63 5) obtained from routine submissions to the Oklahoma Animal Disease Diagnostic Laboratory during 1983–1987 were tested for antimicrobial susceptibility. Minimal inhibitory concentrations (MICs) were determined for the following antimicrobials using commercially prepared microdilution assay materials: ampicillin, cephalothin, chloramphenicol, erythromycin, gentamicin, kanamycin, oxytetracycline, penicillin G, spectinomycin, sulfachlorpyridazine, sulfadimethoxine, and tylosin. Results for isolates from cattle, dogs, horses, and pigs are presented. In only a few instances were differences in MICs apparent among bacterial isolates from different tissues. Aminocyclitol MICs for equine uterine isolates of Klebsiella pneumoniae differed from MICs for isolates from other tissues, and ampicillin, kanamycin, and spectinomycin MICs for bovine fecal isolates of Escherichia coli differed from MICs for isolates obtained from other tissues. In several instances, bimodal distribution of susceptibilities was apparent for ampicillin, kanamycin, and/or oxytetracycline. There was also a bimodal distribution pattern for erythromycin against Pasteurella haemolytica of bovine origin.

Pharmacokinetics of benzathine penicillin G: Serum levels during the 28 days after intramuscular injection of 1,200,000 units

1989 ◽  
Vol 115 (1) ◽  
pp. 146-150 ◽  
Author(s):  
Edward L. Kaplan ◽  
Ximena Berrios ◽  
John Speth ◽  
Thomas Siefferman ◽  
B. Guzman ◽  
...  
Keyword(s):  
Intramuscular Injection ◽  
Serum Levels ◽  
Penicillin G ◽  
Benzathine Penicillin ◽  
Benzathine Penicillin G
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