scholarly journals Investigation of the modulatory role of Bulgarian Mentha Piperita L. oil against radiation-induced oxidative disorders and antioxidant status In Vitro

2018 ◽  
Vol 16 (3) ◽  
pp. 177-187
Author(s):  
Y. Karamalakova
Keyword(s):  
Antioxidant Status ◽  
Radical Scavenging ◽  
Mentha Piperita ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity ◽  
Radiation Induced ◽  
Dpph Scavenging ◽  
Investigation Report

This investigation report on the free radical-scavenging and radio-modulatory properties of Bulgarian M. piperita L. oil. The chemically pure oil (97 %) was tested alone and after expositer to ultraviolet radiation (290-320 nm) and gamma radiation at doses of 5, 10, 20 and 30 Gy. The in vitro antioxidant status studied by different spectrophotometrically methods of M. piperita alone was found to be lower compared to UVB and 10 Gy radiated oil. By direct EPR spectroscopy, single almost symmetrical EPR signals were registered in oil alone (g= 2.00492 ± 0.0003), UVB (g= 2.00586 ± 0.0002) and 10 Gy irradiated (g= 2.0019 ± 0.0002) samples. Antioxidant activity and radical scavenging capacity of M. piperita oil alone and after radiation was also evaluated by the DPPH test. The intensities of the EPR signals of M. piperita oil alone, and irradiated samples demonstrated the possible formation of stable radical structures. The EPR spectra considerably higher after radiation, and excellent DPPH scavenging capacity exhibited by M. piperita indicate good antioxidant potential, radio-modulatory activity and prevent effectively radiation–induced oxidative disorders.

scholarly journals Comparative in vitro antioxidant potential of different parts of Ipomoea asarifolia, Roemer & Schultes, Guiera senegalensis, J. F. Gmel and Anisopus mannii N. E. Brown

2010 ◽  
Vol 46 (2) ◽  
pp. 245-250 ◽  
Author(s):  
Sunday Ene-OjoAtawodi ◽  
Gboyega Suleiman Onaolapo
Keyword(s):  
Radical Scavenging ◽  
Stem Bark ◽  
Therapeutic Effects ◽  
Root Bark ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity ◽  
Guiera Senegalensis ◽  
Ipomoea Asarifolia

In this study, the radical scavenging capacity of Guiera senegalensis, Ipomoea asarifolia and Anisopus mannii were compared. The ascorbic acid equivalent of the stem bark (2.1 mM), leaves (2.05 mM) and root barks (1.89 mM) of Guiera senegalesis are much higher than any part of Ipomoea asarifolia or Anisopus manii. The stem bark, leaves and root bark of Guiera Senegalensis had IC50 of 15.4, 20.0 and 17.0 µL respectively, while corresponding parts of Ipomoea asarifolia showed IC50 of 50, 42 and 65 µL, respectively. These results suggest that Guiera senegalensis and Ipomoea asarifolia possess significant antioxidant capacities to warrant further detailed studies on the role of this property in their therapeutic effects.

Effect of 1-MCP on Bioavailability of Lingwu Long Jujube In Vitro Digestion

2012 ◽  
Vol 554-556 ◽  
pp. 1357-1360
Author(s):  
Zhong Li Jiang ◽  
Ai Li Wang ◽  
Xi Hong Li ◽  
Min Peng Zhu ◽  
Jun Wei Wang
Keyword(s):  
Free Radical ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Total Phenolic ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity ◽  
Control Samples

The present study investigated the effect of 1-MCP on bioavailability of Lingwu long jujube stored at 0 °C for 60 days. At the end of the storage, compared with the control samples, Lingwu long jujube treated with 1-MCP exhibited higher Vc bioaccessibility, total phenolic content and free radical scavenging capacity, which demonstrated that 1-MCP treatment could provide a better effect on maintaining the bioavailability of Lingwu long jujube.

Antioxidative properties of Sambacus nigra extracts

2015 ◽  
Vol 69 (9) ◽  
Author(s):  
Dominika Topoľská ◽  
Katarína Valachová ◽  
Peter Rapta ◽  
Stanislav Šilhár ◽  
Elena Panghyová ◽  
...  
Keyword(s):  
Acute Inflammation ◽  
Radical Scavenging ◽  
Oxidative Degradation ◽  
Protective Effects ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity ◽  
Diammonium Salt ◽  
Dose Dependent ◽  
Oxidative System

AbstractPotential protective effects of elderberry (Sambucus nigra) extracts against oxidative degradation of hyaluronan (HA) were detected in vitro. To induce free-radical-mediated HA degradation, Weissberger’s biogenic oxidative system, which mimics the situation of acute inflammation, was applied. Time- and dose-dependent changes of dynamic viscosity of the HA solutions in the presence and absence of two elderberry extracts produced in 2006 and 2012 were recorded by rotational viscometry (RV). Radical scavenging capacity of both extracts was investigated by the spectrocolorimetric ABTS [2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt] assay and the “inverted” ABTS assay. Oxygen consumption of the system oxidizing HA either in the absence or presence of the elderberry extracts was determined. The results of RV revealed that an addition of the newer extract (2012) promoted the inhibition of HA degradation more markedly compared to the older extract (2006). The same effect of both extracts on ABTS

scholarly journals A Characterization of Content, Composition and Scavenging Capacity of Phenolic Compounds in Parsnip Roots of Various Weight

2014 ◽  
Vol 9 (6) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Nada Č. Nikolić ◽  
Miodrag M. Lazić ◽  
Ivana T. Karabegović ◽  
Gordana S. Stojanović ◽  
Zoran B. Todorović
Keyword(s):  
Phenolic Compounds ◽  
Radical Scavenging ◽  
Total Phenolic ◽  
Root Weight ◽  
Dry Extract ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity ◽  
Dpph Scavenging ◽  
Root Size

The contents, composition and radical scavenging capacity of phenolic compounds from parsnips of various root weights grown in Serbia were examined. The content of phenolic compounds depended on root size, and the highest content was in the group where the samples with the lowest root size were grouped. The content of phenolic compounds varied from 109.7 to 125.3 μmol of chlorogenic acid per g dry extract, i.e.5470.8 to 6245.1 mg per kg fresh weight. Among the identified compounds were quercetin, kaempferol, apigenin and genkwanin glucosides and hydroxycinnamic and caffeoylshikimic acids. The highest antioxidant capacity was found for the group with the lowest root weight; the IC50 values ranged from 1.59 to 2.49 mg mL–1. There was positive correlation between the total phenolic content and scavenging capacity, and the kaempferol glucosides content could be an indicator of DPPH scavenging capacity of parsnip roots.

Impact of the roasting degree of coffee on the in vitro radical scavenging capacity and content of acrylamide

LWT ◽  
2007 ◽  
Vol 40 (10) ◽  
pp. 1849-1854 ◽  
Author(s):  
Carmelina A. Summa ◽  
Beatriz de la Calle ◽  
Marcel Brohee ◽  
Richard H. Stadler ◽  
Elke Anklam
Keyword(s):  
Radical Scavenging ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity

Synthesis, Characterization, Free-radical Scavenging Capacity and Antioxidant Activity of Novel Series of Hydrazone, 1,3,4-oxadiazole and 1,2,4- triazole Derived from 3,5-dimethyl-1H-pyrazole

2019 ◽  
Vol 16 (7) ◽  
pp. 712-720 ◽  
Author(s):  
Khalid Karrouchi ◽  
Saad Fettach ◽  
Smaail Radi ◽  
El bekkaye Yousfi ◽  
Jamal Taoufik ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Free Radical ◽  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity ◽  
Anti Cancer ◽  
Ic50 Values

Background: Pyrazole is an important class of heterocyclic compound, has been shown to exhibit diverse biological and pharmacological activities such as anti-inflammatory, anti-cancer, antioxidant, etc. Methods: In this study, a series of novel 3,5-dimethyl-1H-pyrazole derivatives containing hydrazine 4a-l have been synthesized via the reaction of the 2-(3,5-dimethyl-1H-pyrazol-1-yl)acetohydrazide. All synthesized compounds have been tested for their in vitro antioxidant activities via utilization of 1,1-biphenyl-2-picrylhydrazyl (DPPH) as a free radical scavenging reagent. Results: The data reported herein indicates that compound 4k showed potential radical scavenging capacity and compounds 4f and 4g exhibited best activity for the iron binding while comparing with positive controls. Conclusion: Good activity was noted for some compounds. In particular, compound 4k showed the highest antioxidant activity with IC50 values of 22.79 ± 3.64 and 1.35 ± 0.66 μg/mL in the DPPH and ABTS tests, respectively.

In-vitro Cytotoxic and Antioxidant Activity of Bauhinia racemosa Root

2021 ◽  
pp. 3333-3336
Author(s):  
Aravanan P. ◽  
Jayakumari S
Keyword(s):  
Antioxidant Activity ◽  
Cell Line ◽  
Cell Lines ◽  
Inhibitory Concentration ◽  
Radical Scavenging ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity ◽  
Line Analysis ◽  
Mcf 7

Objective: To evaluate cytotoxic and antioxidant activity of the plant Bauhinia racemosa root by in-vitro cell line analysis. Methods: MCF-7 cell lines were used for the study to find the inhibitory concentration of the extract. DPPH and NO scavenging assays were performed to study the antioxidant nature of the extract. Results and Conclusion: In MCF-7 cell line cytotoxicity effect was observed in tested sample concentrations in 48 hours treatment, it also revealed that increased concentration of drug shown increased cytotoxicity over the MCF-7 cell lines. DPPH and NO scavenging Assay revealed a concentration dependent radical scavenging capacity of the tested sample concentrations of Bauhinia racemosa root spectrophotometrically.

An in vitro study of the peroxyl and hydroxyl radical scavenging capacity of the calcium antagonist amlodipine

2004 ◽  
Vol 58 (8) ◽  
pp. 423-426 ◽  
Author(s):  
Ferdinando Franzoni ◽  
Gino Santoro ◽  
Francesco Regoli ◽  
Yvonne Plantinga ◽  
Francesca R. Femia ◽  
...  
Keyword(s):  
Calcium Antagonist ◽  
Hydroxyl Radical ◽  
Radical Scavenging ◽  
In Vitro Study ◽  
Vitro Study ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity
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