scholarly journals Effect of hypertonicity on the dynamic state of erythrocyte spectrin network as revealed by thermal dielectroscopy

2016 ◽  
Vol 14 (1) ◽  
pp. 96-102 ◽  
Author(s):  
B. Paarvanova ◽  
I. Ivanov
Keyword(s):  
Dynamic State ◽  
Spectrin Network

Pinocytotic-Like Forms of Mitochondria From Rat Anterior Pituitary

1968 ◽  
Vol 26 ◽  
pp. 146-147
Author(s):  
Burton B. Silver
Keyword(s):  
Electron Micrographs ◽  
Conformational Changes ◽  
Anterior Pituitary ◽  
Dynamic State ◽  
Surrounding Cell ◽  
The Matrix ◽  
The Moment ◽  
Cell Medium ◽  
Sectioned Tissue ◽  
State Of Activity

Sectioned tissue rarely indicates evidence of what is probably a highly dynamic state of activity in mitochondria which have been reported to undergo a variety of movements such as streaming, divisions and coalescence. Recently, mitochondria from the rat anterior pituitary have been fixed in a variety of configurations which suggest that conformational changes were occurring at the moment of fixation. Pinocytotic-like vacuoles which may be taking in or expelling materials from the surrounding cell medium, appear to be forming in some of the mitochondria. In some cases, pores extend into the matrix of the mitochondria. In other forms, the remains of what seems to be pinched off vacuoles are evident in the mitochondrial interior. Dense materials, resembling secretory droplets, appear at the junction of the pores and the cytoplasm. The droplets are similar to the secretory materials commonly identified in electron micrographs of the anterior pituitary.

Proteomics: Opportunities and Challenges

2011 ◽  
Vol 3 (4) ◽  
pp. 1165-1172 ◽  
Author(s):  
Parag A Pathade ◽  
Vinod A Bairagi ◽  
Yogesh S. Ahire ◽  
Neela M Bhatia
Keyword(s):  
Biomedical Research ◽  
Therapy Monitoring ◽  
Dynamic State ◽  
Data Sets ◽  
Protein Markers ◽  
Drug Target Discovery ◽  
Proteomic Data ◽  
Cell Tissue ◽  
A Cell ◽  
Analytical Tools

‘‘Proteomics’’, is the emerging technology leading to high-throughput identification and understanding of proteins. Proteomics is the protein equivalent of genomics and has captured the imagination of biomolecular scientists, worldwide. Because proteome reveals more accurately the dynamic state of a cell, tissue, or organism, much is expected from proteomics to indicate better disease markers for diagnosis and therapy monitoring. Proteomics is expected to play a major role in biomedical research, and it will have a significant impact on the development of diagnostics and therapeutics for cancer, heart ailments and infectious diseases, in future. Proteomics research leads to the identification of new protein markers for diagnostic purposes and novel molecular targets for drug discovery.  Though the potential is great, many challenges and issues remain to be solved, such as gene expression, peptides, generation of low abundant proteins, analytical tools, drug target discovery and cost. A systematic and efficient analysis of vast genomic and proteomic data sets is a major challenge for researchers, today. Nevertheless, proteomics is the groundwork for constructing and extracting useful comprehension to biomedical research. This review article covers some opportunities and challenges offered by proteomics.   

scholarly journals The transport and dynamic state of exogenous glycerol- and palmitic acid-labeled tripalmitin

1960 ◽  
Vol 1 (3) ◽  
pp. 241-247
Author(s):  
Raymond Reiser ◽  
Mary C. Williams ◽  
Mary F. Sorrels
Keyword(s):  
Palmitic Acid ◽  
Dynamic State

scholarly journals Structure of end moraines and dynamics of the recession phase of the Warta Stadial ice sheet, Kłodawa Upland, Central Poland

2020 ◽  
Vol 12 (1) ◽  
pp. 753-763
Author(s):  
Magdalena Anna Drążczyk
Keyword(s):  
Cross Sections ◽  
Ice Sheet ◽  
Geological Mapping ◽  
Dynamic State ◽  
Central Poland ◽  
The Creation ◽  
Key Sites ◽  
Marginal Zones

AbstractThe occurrence of end moraines reflects the dynamics of an ice sheet, and their inner structure is determined by processes taking place in marginal zones. In the southern part of the Kłodawa Upland of Central Poland, such moraines were formed, but opinions conflict as to their origin, including the influence of local transgression of the ice sheet, as well as its areal and frontal recession. The primary aim of this article is to analyse the inner structure of forms to define the dynamic state of the Warta Stadial ice sheet of the Odra Glaciation (Saalian). The conducted research includes fieldwork at four key sites, where lithofacial analysis was performed, as well as a geomorphological and geological mapping that included two cross-sections in greater detail. In exposures, the work focused on deformed structures of sediments. Description of key sites was extended by the creation and the analysis of general geological cross-sections. Considering the results of the research, the Kutno end moraines should not be classified as push moraines – they were revealed to be accumulative in character.

scholarly journals Limits of reproducibility and hydrodynamic noise in atmospheric regional modelling

2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Beate Geyer ◽  
Thomas Ludwig ◽  
Hans von Storch
Keyword(s):  
Regional Climate Model ◽  
Computer Architecture ◽  
Climate Model ◽  
Initial Conditions ◽  
Regional Climate ◽  
Quality Criterion ◽  
Dynamic State ◽  
Regional Modelling ◽  
Simulation Results ◽  
Mathematical Operations

AbstractReproducibility of research results is a fundamental quality criterion in science; thus, computer architecture effects on simulation results must be determined. Here, we investigate whether an ensemble of runs of a regional climate model with the same code on different computer platforms generates the same sequences of similar and dissimilar weather streams when noise is seeded using different initial states of the atmosphere. Both ensembles were produced using a regional climate model named COSMO-CLM5.0 model with ERA-Interim forcing. Divergent phase timing was dependent on the dynamic state of the atmosphere and was not affected by noise seeded by changing computers or initial model state variations. Bitwise reproducibility of numerical results is possible with such models only if everything is fixed (i.e., computer, compiler, chosen options, boundary values, and initial conditions) and the order of mathematical operations is unchanged between program runs; otherwise, at best, statistically identical simulation results can be expected.

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