Порівняльна оцінка препаратів фенбендазолу за інвазії курей-несучок нематодами Heterakis gallinarum
The article presents data on the effectiveness of two fenbendazole-based drugs for oral application: «Feboral» (in the form of a solution) and «Brovadazol 20%» (the reference drug in the form of powder). For this purpose, 420-day-old chickens were examined by a flotation coproscopic method in order to detect intestinal invasions. The therapeutic efficacy of the drugs was determined according to the data of the coproscopic examinations carried out using the modified quantitative McMaster counting method. The study of the efficacy of «Febboral» and «Brovadazol 20%» preparations was performed under the conditions of vivarium of the State scientific-research control institute of veterinary medicinal products and feed additives.During the experiment birds of experimental groups used preparations on the basis of fenbendazole: hens of the first experimental group, the drug «Feboral» was poured out with water (1.0 ml of the preparation for 10 kg of b. w., twice for two days), the second – the drug «Brovadazol 20%» they were given with food (0.5 g of the preparation at 10 kg b. w., for five days). Birds in the control group were given water and food without the contents of drugs.According to the results of research in hens were found invasion by Heterakis galinarum. The average rate of invasion of hens by nematodes during treatment with drugs was 176 eggs per 1 g of litter. In the hens of the first and second experimental groups, the average intensity of the helminth infestation on the seventh day of the experiment was 84.5 eggs per 1 g of litter, while the intensity of the infection of the control group was 211 eggs per 1 g of litter. On the fourteenth day of the experiment, the excretion of eggs from the pathogen in the hens of both experimental groups was not noted, while in the hens of the control group, the intensity of the invasion amounted to 238 eggs heterakis in 1 gram of litter.Consequently, the extenseffectivity of the drug «Febboral» and the reference drug «Brovadazol 20%» for heterakoses of chickens was 100%.