scholarly journals Experimental study action autostrains Aerococcus viridans on the model Pseudomonas infection

2017 ◽  
Vol 8 (3) ◽  
pp. 313-316
Author(s):  
D. O. Stepanskyi ◽  
G. M. Kremenchutskyi ◽  
I. P. Koshova
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Clinical Signs ◽  
Solution Concentration ◽  
Control Group ◽  
Infection Model ◽  
Treatment And Prevention ◽  
Aerococcus Viridans ◽  
Group A ◽  
Recovery Dynamics ◽  
Experimental Group

The paper presents the results of a study of the action of Aerococcus autostrains on the model of a chronic blue pus infection. For the study of the action of Aerococcus autosymbiont strains on Pseudomonas aeruginosa, three of the most biochemically and antagonistically active isolates were selected: 1) 5m2015 (isolated from mice); 2) 3k2015 (isolated from rats); 3) 3ch2015 (isolated from humans). Experiments were conducted on 84 white outbred mice weighing 16–17 g, 60 were used as the experimental, and 24 as the control group. In the experimental group of animals, infected wounds were treated by Aerococcus autosymbiont strains once daily (0.2 billion ml–1) till recovery. The drug was administered under the eschar with a syringe. In the control animals the wound was treated by isotonic sodium chloride solution (concentration 0.9%) with the same route of administration and for the same period of time. It was found that from the very first days of application of Aerococci autosymbiont strains, perifocal inflammation was less severe in most animals in the research group compared with the control group. Starting from the fourth day of usage of Aerococcus autosymbiont strains the number of pseudomonades, contained in secretions from wounds in the experimental group of mice was significantly lower than in the control animals. It was revealed that in case of application of Aerococcus strain (5m2015) isolated from mice, the animals had better indicators of recovery, dynamics of local clinical signs of inflammation and the number of pseudomonades contained in the wound in comparison with other Aerococcus autostrains isolated from rats and humans. The wounds purified from pus and covered with dry eschar faster. For example, wounds completely healed with dry eschar rejection by the 11th day of observation in 44 of 58 surviving mice (75.9%). In the control group a similar pattern was observed in only 3 of 17 mice (17.6%) by the that period. The number of Pseudomonas aeruginosa (equivalent to 1 ml of secretions wounds), expressed in logarithms, was 5.00 ± 0.16 on average on the 4th day in the treated mice, while the control group had the same amount of pseudomonades detected in the wounds (lg 5.22 ± 0.38; lg 5.12 ± 0.30) only on the 13–14th days of observation. We found different activity of strains, depending on the origin of microorganism and type host. Aerococcus viridians autosymbionts showed higher rates in the study of their activity in terms of the blue pus infection model in the treatment of the host and lower activity in treatment.of other species. The obtained data may warrant further study of application of Aerococcus autostrains for treatment and prevention of wound infection caused by pseudomonades. 

scholarly journals Parenting Stress and Need Assessment of Families with Disabled Children across Himachal Himalaya

2015 ◽  
Vol 3 (2) ◽  
pp. 38 ◽  
Author(s):  
Randhir S. Ranta ◽  
Vijay Kumar Sharma ◽  
Pankaj Gupta
Keyword(s):  
Parenting Stress ◽  
Assessment Scale ◽  
Control Group ◽  
Disabled Children ◽  
Normal Children ◽  
Need Assessment ◽  
Significant Difference ◽  
Group A ◽  
And Control ◽  
Experimental Group

The study pertains to the parenting stress, which is believed to be the resultant of child disability and further assesses the needs of the families across selected pockets of Himachal Himalaya. Perceived Stress Questionnaire (PSQ) and Need Assessment Scale were used for the purpose. For assessing the stress level among the parents, PQS was administered among two hundred parents having disabled children, herein called experimental group and two hundred parents with normal children, herein called control group. A three point Need assessment scale was used to measure the needs of 200 families on five different parameters. The result of t-test shows the significant difference between experimental and control groups indicating that the parents of disabled children experience more stress than their control counterpart. The study indicates that people need proper guidance and information regarding a child’s disability, nutritional requirements of a child, vocational training and child management. There is a need for proper counselling for parents suffering from stress and creating consciousness among parents of children with disabilities and in the society.

Histopathologic lesions in conventional pigs experimentally infected with Haemophilus parasuis serovar 5

2015 ◽  
Vol 43 (02) ◽  
pp. 91-96 ◽  
Author(s):  
R.-L. Austin-Busse ◽  
A. Ladinig ◽  
G. Balka ◽  
S. Zoels ◽  
M. Ritzmann ◽  
...  
Keyword(s):  
Clinical Signs ◽  
Control Group ◽  
Post Inoculation ◽  
Haemophilus Parasuis ◽  
Tissue Samples ◽  
Group A ◽  
Pathologic Lesions ◽  
Group B ◽  
Kidney Lesions ◽  
Challenge Group

Summary Objective: In the present study various tissues of pigs were investigated for the presence of histopathologic lesions after an experimental infection with Haemophilus (H.) parasuis serovar 5. Material and methods: Conventional pigs (n = 36) were divided into a control group B (n = 9) and a challenge group A (n = 27), which was infected intratracheally. Pigs that did not die prior to study termination were euthanized on day 14 post inoculation. Postmortem samples of the lung, heart, liver, kidney, spleen, left tarsal joint capsule and brain were collected. Results: All but one pig with detectable histopathologic lesions (n = 11) showed typical macroscopic changes. Histopatho logic examination of all tissue samples identified pyelitis (n = 10), synovitis (n = 7) and meningitis (n = 7) and all those animals were euthanized prior to study termination. No histopathologic lesions were found in pigs of the control group. The correlations between pyelitis and meningitis, pyelitis and synovitis and synovitis and meningitis were significant (p < 0.001). No significant correlation could be observed between the histopathologic and the clinical examination of the joints. The investigation of samples from the joints by PCR was not significantly correlated with the observed synovitis. The clinical observation of neurologic signs was significantly correlated with meningitis (p = 0.03). A significant correlation (p < 0.001) could be detected between meningitis and the detection of H. parasuis by PCR in brain samples. Conclusions: H. parasuis constantly causes clinical signs and pathologic lesions as soon as it infects the brain while it can infect the joints without causing histopathologic lesions. Pigs with histopathologic lesions do not always show typical clinical signs. Only few studies described the finding of kidney lesions in pigs with Glässer’s disease and this is the first study to describe a pyelitis in pigs experimentally infected with H. parasuis. The observed pyelitis mainly occurred in acute cases.

EFFECT OF YOGA ON CARDIOVASCULAR EFFICIENCY

2019 ◽  
pp. 12-16
Author(s):  
Brij Bhushan Singh ◽  
Shubi Mirja ◽  
Samiya Husain
Keyword(s):  
Statistical Technique ◽  
Step Test ◽  
Control Group ◽  
Significant Difference ◽  
Post Test ◽  
Group A ◽  
Cardio Vascular ◽  
Level Of Significance ◽  
Group B ◽  
Experimental Group

The purpose of this study was to investigate the effects of yogic practices on cardio-vascular efficiency. Material and methods: Total Forty (40) subject’s boys/girls were selected as the sample of the study through the random sampling and their age ranged between 20 to 25 years from the Department of Physical Education, Aligarh Muslim University, Aligarh. The subjects were divided into two groups comprising 20 subjects in each group, namely group “A” (the experimental group) performs yogic practices (Asanas, Pranayamas and Kriyas) and group “B” (the control group) served as control. Statistical technique: for the assessment of the cardiovascular efficiency through Harvard step test pre and post-test was conducted and t-test was applied for the analysis. Result: revealed that there exist a significant difference between group A and group B, at .05 level of significance. On the basis of the pre and post-test among experimental and control group, experimental group found better than the control group on cardiovascular efficiency and significant result were found in this study.

EFFECT OF ACCUPRESSURE PEN ON DISTANCE VARIABLE IN SCIATICA PATIENTS -A RANDOMIZED CONTROL TRIAL

2021 ◽  
pp. 28-31
Author(s):  
Urja S. Vaidya ◽  
Roshani S. Patel
Keyword(s):  
Randomized Control Trial ◽  
Stride Length ◽  
Step Length ◽  
Control Group ◽  
Exclusion Criteria ◽  
Parametric Test ◽  
Group A ◽  
Randomized Control ◽  
Experimental Group ◽  
Distance Variable

Background: Sciatica is a radiating pain which is treated with manual accupressure and after a time electro accupressure came into introduction. Aim And Objective: Aim: To nd out the effectiveness of accupressure pen to improve the distance variable To nd out the effect of Objective: accupressure pen on pain and distance variable in sciatica patient To compare the experimental group to the control group On the basis of Method: inclusion and exclusion criteria 30 participants were selected. They were treated with electro accupressure pen for 3 alternative days / week for 3 weeks, after that re-assessment was taken with NPRS, Slump and Distance variables. The data was analyzed using SPSS Version Results: 21.Parametric test was used .In Group A improvement was seen Accupressure Conclusions: pen is effective to reduce pain and improve step length and stride length in Sciatica Patients

scholarly journals Ameliorative effects of Spinacia oleracea on sperm morphology, count, and motility by normalizing the obesity-induced oxidative stress in Sprague Dawley rats

2020 ◽  
Vol 14 (03) ◽  
pp. 124-127
Author(s):  
Somia Iqbal ◽  
Noman Sadiq ◽  
Saad Siddiqui ◽  
Hira Iqbal
Keyword(s):  
Sperm Concentration ◽  
Treated Group ◽  
Sperm Parameters ◽  
Control Group ◽  
Sprague Dawley ◽  
Normal Morphology ◽  
Sprague Dawley Rats ◽  
Group A ◽  
Group B ◽  
Experimental Group

Background: Obesity is a prevailing metabolic disorder that affects the functioning of the male reproductive system. Excessive adipose tissue enhances reactive oxygen species generation and is linked with male infertility. Spinach has demonstrated antioxidant effects. The present study was conducted to determine the antioxidant effects of spinach on sperm parameters in obese Sprague Dawley rats. Subjects and methods: This randomized control study was conducted at the animal house of the National Institute of Health Islamabad, Islamic International Medical College, Cosmesurge International Hospital, Rawalpindi, and Apollo lab, Islamabad, Pakistan from April 2016 to March 2017. Forty male Sprague Dawley rats having an age of 8 weeks and weight 160-200g were tagged from number 1 to 40. Every third rat was randomly allocated to control Group A (n=13) and remaining into the Experimental group (n=27). Rats of control Group A was given a standard diet while a high-fat diet was given to Experimental group rats to induce obesity for the duration of six weeks. Weight (g) was measured weekly and obesity was confirmed when rats attain more than 20% weight when compared with that of rats of control Group A. Then, after obesity induction, the experimental group was alienated into the obesity control group (Group B) and spinach treated group (Group C). For sample, rats of Group A and Group B were sacrificed, and the cauda epididymis of each rat was placed in a Petri dish containing normal saline and cut into pieces to allow the release of sperm and then sperm parameters (sperms concentration, motility, and morphology) were recorded under the microscope. Then, spinach (5% hot water extract) along with the persistence of fat diet was administered to Group C for 4 weeks and finally, sperm parameters were measured in this group. Results: Sperm concentration/ml, motility (%), and normal morphology (%) of Group B rats were significantly decreased as compared to Group A rats. However, sperm concentration/ml, motility (%), and normal morphology (%) of Group C (spinach treated group) rats was significantly increased (p<0.001) as compared to Group B (obesity control group) rats after administering spinach. Conclusion: The addition of Spinach in a normal diet regimen restores normal sperm morphology, improves sperm motility and concentration.

scholarly journals Peningkatan Keterampilan Sosial dan Motorik Halus Anak Melalui Pembelajaran Berbasis Proyek

2021 ◽  
Vol 1 (1) ◽  
pp. 14-33
Author(s):  
Wuni Arum Sekar Sari
Keyword(s):  
Emotional Development ◽  
Project Based Learning ◽  
Fine Motor ◽  
Control Group ◽  
Social Emotional Development ◽  
Social Emotional ◽  
Control Group Design ◽  
Post Test ◽  
Group A ◽  
Experimental Group

This study examines the effect of project-based learning on children’s social-emotional development and children’s fine motoric development. This study uses a Quasi-Experimental Design. Control-Group Design (Pre-test and Post Test) or Nonequivalent [Pretest and Post Test] Control-Group Design, the experimental group (A) and the control group (B), were selected without a random assignment procedure. In these two groups, both pretest and posttest were carried out. Only the experimental group (A) was treated. This research was conducted at RA Uniform Debit and RA Kusuma Mulia, Ngino, Plemahan, Kediri. Data were collected using observation sheets, descriptive statistical data analysis, and paired t-test with alpha <0.05.  Based on the results of different tests with the Paired t-test, the Sig. As much as 0.000, where this value is less than 0.05, reject H1 and accept H0, there are differences in social-emotional development and fine motor skills between before (pretest) and after (posttest) getting project-based learning the experimental group and the control group. The average value shows that the social-emotional development after being given the Project-Based learning was more significant than the social-emotional development, namely 26.03> 20.44 in the experimental group and 22.10> 20.23 in the control group. Likewise, fine motor development before being given the Project-Based learning, namely 14.97> 11.84 in the experimental group and 13.03> 11.97 in the control group. This means that the project-based learning given to RA students in Plemahan, Kediri is more effective than learning in the control group.

scholarly journals Comparison of a novel herbal skin care ointment with regular ointments to treat skin around the abdominal stoma: A clinical trial study

2019 ◽  
Author(s):  
Maryam Hajikari ◽  
Soheila Mojdeh ◽  
Mohsen Shariari
Keyword(s):  
Data Collection ◽  
Herbal Product ◽  
Gastric Ulcers ◽  
Control Group ◽  
Skin Ulcers ◽  
Significant Difference ◽  
Group A ◽  
The Mean ◽  
Experimental Group

Introduction The incidence of gastric ulcers in patients with abdominal stoma is high and affects the quality of patients’ life. Aim To evaluate the effect of Adib herbal ointment containing chamomile rose, black nightshade origin versus Comfeel and Conveen ointments on the skin of abdominal stoma. Material and methods This is a clinical study in which the volunteers were stoma patients. Study group consisted of 52 qualified subjects, 26 were included in the experimental group and 26 in the control group. A 2-part questionnaire was used for the data collection. The 1st part was demographic information. The 2nd part of the data collection was evaluated according to the pressure ulcer scale for healing (PUSH) tool, which used for examining skin ulcers around the stoma. P ≤ 0.05 was considered as a significant. Results and discussion The results of the Mann–Whitney test showed that between the mean score of the total score of the wound before intervention (P = 0.92) and on the 3rd day (P = 0.476), 6th (P = 0.222), 9th (P = 0.11) and 12th (P = 0.418), there was no significant difference between the control and test groups. Also, the Friedman test (intra-group) also showed that between the mean score of the total score of the wound before the intervention and the 3rd, 6th, 9th and 12th days in the control group (P = 0.0001) and in the experimental group (P = 0.0001) There was a significant statistical difference. Conclusions Based on the study, Adib herbal ointment could be recommended for the treatment of stoma to the skin as an herbal product as other common treatments.

Effectiveness of Peer Tutoring Program on Students’ Academic Performance for Engineering Course

2021 ◽  
Vol 6 (1) ◽  
pp. 71
Author(s):  
Fei Ha Chiew ◽  
Clotilda Petrus ◽  
Siti Zaidah Othman ◽  
Joe Davylyn Nyuin ◽  
Ung Hua Lau
Keyword(s):  
Peer Tutoring ◽  
Intervention Program ◽  
Solid Mechanics ◽  
Practical Significance ◽  
Control Group ◽  
Tutoring Program ◽  
Significant Difference ◽  
Group A ◽  
And Control ◽  
Experimental Group

This study investigated the effectiveness of a peer tutoring program that was implemented for Basic Solid Mechanics course, as an intervention program to improve students’ performance in the course. Ten tutors were chosen to provide tutoring services to an experimental group of 36 tutees. Tutees were required to answer an entry test before the intervention program, and another exit test after the program. A control group which shared the same instructor in their lecture classes was included in the study. Comparison between the performances for entry and exit tests of both experimental and control groups were made. Analyses showed an increase in the percentage of students that passed the exit test from the experimental group. The average marks for the experimental group in the exit test also increased, compared to their marks in the entry test. A Mann- Whitney U test conducted indicated a significant difference between the gain scores of the experimental group and control group. A further metaanalysis revealed a large effect size, signaling the practical significance of the results. The findings demonstrated the effectiveness of the peer tutoring intervention program on students’ performance of the course.

MONIZEN FORTE FOR LAMBS PARASIT-IC DISEASES

2020 ◽  
Vol 2 ◽  
pp. 84-87
Author(s):  
E. S. Engasheva ◽  
◽  
V. I. Kolesnikov ◽  
Keyword(s):  
Clinical Signs ◽  
Live Weight ◽  
Control Group ◽  
Not Given ◽  
The North ◽  
Condi Tions ◽  
High Infection ◽  
Mucous Discharge ◽  
And Control ◽  
Experimental Group

The Monizen Forte test for parasitic sheep diseases was tested under production condi-tions on 460 lambs of the North Caucasian breed, with a live weight of 25-30 kg, with high infection with nematodes, cestodes and larvae of the nasopharyngeal gadfly (Oestrus ovis), which were given orally in a mixture with half the normal rate of concentrated feed, the test drug in a dose of 1 ml per 20 kg of the animal weight. Experienced (20 ani-mals) and control (10 animals) groups of lambs with an average live weight of 28 kg were selected from these lambs according to the principle of analogues. To the lambs of the control group, the drug was not given. 10 days after administration of the drug by clini-cal and coprological studies, it was found that the lambs of the experimental group, the intensity of nematode invasion decreased and the drug’s intensity (IE) was 96.7%, and the extensivity (EE) was 95%. The lambs of the experimental group before the introduction of the drug were 40% invaded with moniesia and 50% dictiocauli, and after using Monizen Forte they were released - the ex-tensibility (EE) was 100%. Lambs of the control (untreated) group, the intensity and extent of infection with nematodes and ces-todes remained at the same level as at the beginning of the experiment. All 10 lambs (50%) of the experimental group, the clinical signs of estrosis (sneezing, snorting, serous-mucous discharge from the nose) disap- peared, and the lambs of the control group have these clinical signs persisted.

An importance of matrix-metalloprotease determination in urine of patients with bladder cancer

2021 ◽  
Vol 1 (1) ◽  
pp. 30-32
Author(s):  
Vladimir N. Tkachuk ◽  
Adel S. Al-Shukri ◽  
Dmitriy I. Danilchenko
Keyword(s):  
Bladder Cancer ◽  
Control Group ◽  
Depth Of Invasion ◽  
Matrix Metalloprotease ◽  
Cancer Occurrence ◽  
Bladder Diseases ◽  
Neoplastic Process ◽  
Group A ◽  
Experimental Group

The aimof this work is to estimate an influence of a depth and an extent of differentiation of neoplastic process on 2 and 9 matrix-metalloprotease levels in urine of patients with bladder cancer. Patients and methods.71 patients with bladder cancer have been investigated. 14 patients with chronic cystitis were included in an experimental group and 45 patients without bladder diseases were included in a control group, patients without urinary tract obstructions and infections were included in a control group. A level of metalloprotease was identified by a cimographic method. Results.It has been proved that enzymes MMP-2 and MMP-9 of urine proteolysis are high sensitive markers of bladder cancer occurrence and their concentration depends on a depth of invasion and an extent of tumor differentiation, and shows a disease course prognosis. Conclusion.It is reasonably to identify MMP-2 and MMP-9 of urine by the cimographic method for diagnostics and noninvasive determination of a depth of invasion and an extent of bladder cancer differentiation.

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