scholarly journals 2020 Asian Pacific Society of Cardiology Consensus Recommendations on Antithrombotic Management for High-risk Chronic Coronary Syndrome

2021 ◽  
Vol 16 ◽  
Author(s):  
Jack Wei Chieh Tan ◽  
Derek P Chew ◽  
David Brieger ◽  
John Eikelboom ◽  
Gilles Montalescot ◽  
...  

The unique characteristics of patients with chronic coronary syndrome (CCS) in the Asia-Pacific region, heterogeneous approaches because of differences in accesses and resources and low number of patients from the Asia-Pacific region in pivotal studies, mean that international guidelines cannot be routinely applied to these populations. The Asian Pacific Society of Cardiology developed these consensus recommendations to summarise current evidence on the management of CCS and provide recommendations to assist clinicians treat patients from the region. The consensus recommendations were developed by an expert consensus panel who reviewed and appraised the available literature, with focus on data from patients in Asia-Pacific. Consensus statements were developed then put to an online vote. The resulting recommendations provide guidance on the assessment and management of bleeding and ischaemic risks in Asian CCS patients. Furthermore, the selection of long-term antithrombotic therapy is discussed, including the role of single antiplatelet therapy, dual antiplatelet therapy and dual pathway inhibition therapy.

2021 ◽  
Vol 16 ◽  
Author(s):  
Jack WC Tan ◽  
Derek P Chew ◽  
Muhamad Ali SK Abdul Kader ◽  
Junya Ako ◽  
Vinay K Bahl ◽  
...  

The unique characteristics of patients with acute coronary syndrome in the Asia-Pacific region mean that international guidelines on the use of dual antiplatelet therapy (DAPT) cannot be routinely applied to these populations. Newer generation P2Y12 inhibitors (i.e. ticagrelor and prasugrel) have demonstrated improved clinical outcomes compared with clopidogrel. However, low numbers of Asian patients participated in pivotal studies and few regional studies comparing DAPTs have been conducted. This article aims to summarise current evidence on the use of newer generation P2Y12 inhibitors in Asian patients with acute coronary syndrome and provide recommendations to assist clinicians, especially cardiologists, in selecting a DAPT regimen. Guidance is provided on the management of ischaemic and bleeding risks, including duration of therapy, switching strategies and the management of patients with ST-elevation and non-ST-elevation MI or those requiring surgery. In particular, the need for an individualised DAPT regimen and considerations relating to switching, de-escalating, stopping or continuing DAPT beyond 12 months are discussed.


2021 ◽  
Vol 16 ◽  
Author(s):  
Luokai Wang ◽  
Tee Joo Yeo ◽  
Benedict Tan ◽  
Bernard Destrube ◽  
Khim Leng Tong ◽  
...  

Sports-related sudden cardiac death is a rare but devastating consequence of sports participation. Certain pathologies underlying sports-related sudden cardiac death could have been picked up pre-participation and the affected athletes advised on appropriate preventive measures and/or suitability for training or competition. However, mass screening efforts – especially in healthy young populations – are fraught with challenges, most notably the need to balance scarce medical resources and sustainability of such screening programmes, in healthcare systems that are already stretched. Given the rising trend of young sports participants across the Asia-Pacific region, the working group of the Asian Pacific Society of Cardiology (APSC) developed a sports classification system that incorporates dynamic and static components of various sports, with deliberate integration of sports events unique to the Asia-Pacific region. The APSC expert panel reviewed and appraised using the Grading of Recommendations Assessment, Development, and Evaluation system. Consensus recommendations were developed, which were then put to an online vote. Consensus was reached when 80% of votes for a recommendation were agree or neutral. The resulting statements described here provide guidance on the need for cardiovascular pre-participation screening for young competitive athletes based on the intensity of sports they engage in.


2021 ◽  
Vol 16 ◽  
Author(s):  
Natalie Koh ◽  
Brian A Ference ◽  
Stephen J Nicholls ◽  
Ann Marie Navar ◽  
Derek P Chew ◽  
...  

The prevalence of dyslipidaemia has been increasing in the Asia-Pacific region and this is attributed to dietary changes and decreasing physical activity. While there has been substantial progress in dyslipidaemia therapy, its management in the region is hindered by limitations in awareness, adherence and healthcare costs. The Asian Pacific Society of Cardiology (APSC) developed these consensus recommendations to address the need for a unified approach to managing dyslipidaemia. These recommendations are intended to guide general cardiologists and internists in the assessment and treatment of dyslipidaemia and are hoped to pave the way for improving screening, early diagnosis and treatment. The APSC expert panel reviewed and appraised the evidence using the Grading of Recommendations Assessment, Development, and Evaluation system. Consensus recommendations were developed, which were then put to an online vote. The resulting consensus recommendations tackle contemporary issues in the management of dyslipidaemia, familial hypercholesterolaemia and lipoprotein(a) in the Asia-Pacific region.


Author(s):  
Yuchen Shi

The Asia-Pacific region is one of the most important “poles” of world economic development, but the region lacks a mechanism for regional integration and coordination to counter challenges and risks. ASEAN is the earliest example of integration in the region. Thanks to the active promotion and efforts of this organization regional integration in East Asia has formed a new development model, which gives a new idea for the development of regional integration in the Asia-Pacific region.


Author(s):  
S. Sevast'yanov

Since late 80-s of XX century active integration processes are undergoing in the Asia-Pacific region. Asian countries are trying to minimize the negative effects of the shocking changes in the system of international relations and of the global or regional economic crises. United States are quite actively involved in the regional integration. By using the “old” and creating “new” associations USA try to oppose the growing influence of China here. Russia, for its part, is also looking for the effective ways to connect to the Asian integration projects that can improve the socio-economic situation of the population of the Far East and will enable us to make a significant contribution to the development of economic cooperation in the Asia-Pacific region.


2016 ◽  
Vol 202 ◽  
pp. 861-869 ◽  
Author(s):  
Mark Y. Chan ◽  
Xin Du ◽  
David Eccleston ◽  
Changsheng Ma ◽  
Padinhare P. Mohanan ◽  
...  

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