Established and Emerging Applications of Magnetic Resonance Late Enhancement Imaging in Cardiology

2007 ◽  
Vol 3 (1) ◽  
pp. 58
Author(s):  
Frank Grothues ◽  
2012 ◽  
Vol 8 (2) ◽  
pp. 101
Author(s):  
Brage H Amundsen ◽  
Anders Thorstensen ◽  
Asbjørn Støylen ◽  
◽  
◽  
...  

The aim of this article is to discuss the present and future potential of deformation imaging by echocardiography and scar visualisation by magnetic resonance imaging (MRI) in patients with coronary artery disease (CAD). The two methods are clearly different: one is concerned with function, the other with morphology. Echocardiography, with its versatility of methods and high applicability, will continue to be the workhorse in cardiac imaging of patients with CAD. Important additional information can be extracted from deformation imaging methods, especially due to the high temporal resolution in tissue Doppler. Deformation measurements in 3D images are still limited by their lower resolution compared with 2D but will continue to improve. The standardisation of image analysis and the collaboration within the echocardiographic community to conduct larger studies will be important tasks in the attempt to establish evidence for the new methods. Late enhancement MRI is a method with unique properties and will continue to be an important alternative in selected patients and settings, as well as an invaluable research tool.


2013 ◽  
Vol 91 (8) ◽  
pp. 617-624 ◽  
Author(s):  
Edit Lukács ◽  
Balázs Magyari ◽  
Levente Tóth ◽  
Örs Petneházy ◽  
Zsolt Petrási ◽  
...  

The diagnostic characteristics of electromechanical mapping (EMM) were evaluated in porcine myocardial infarction (MI) models with the parallel application of cardiac magnetic resonance imaging (cMRI) from the aspect of different pathophysiology and localization. Balloon occlusion in the left anterior descending coronary artery (LAD balloon group) or coil deployment in the LAD (LAD coil group) or circumflex artery (Cx coil group) was applied percutaneously in 16 domestic pigs. Regional left ventricular viability data were captured via cMRI and EMM. The unipolar voltage (UV) value was significantly decreased in segments containing transmural and subendocardial late enhancement compared with viable segments in the LAD balloon, LAD coil, and Cx coil groups. Receiver operating characteristic analysis revealed area under the curve values of 0.809 and 0.691 in the LAD infarct territory, and 0.864 and 0.855 in the Cx infarct territory for the UV compared with cMRI viability results as transmural late enhancement or viable tissue and subendocardial late enhancement or viable tissue, respectively. In conclusion, the UV value detected the presence of scar tissue with differential transmural extent and which represented proper diagnostic features both in the reperfused and nonreperfused models. This data could provide additional benefit in the clinical use of EMM for diagnostic purposes.


2014 ◽  
Vol 83 (4) ◽  
pp. 660-664 ◽  
Author(s):  
Patrick Doeblin ◽  
Rene Schilling ◽  
Moritz Wagner ◽  
Reny Luhur ◽  
Alexander Huppertz ◽  
...  

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