Case 2: Refractory Respiratory Failure and Pneumothorax in a Full-Term Newborn

NeoReviews ◽  
2018 ◽  
Vol 19 (2) ◽  
pp. e109-e111 ◽  
Author(s):  
Benjamin D. Reed ◽  
Shreyas Arya ◽  
Kevin R. Dufendach ◽  
Daniel Leino
2020 ◽  
Vol 11 ◽  
Author(s):  
Martin Jouza ◽  
Tomas Jimramovsky ◽  
Eva Sloukova ◽  
Jakub Pecl ◽  
Anna Seehofnerova ◽  
...  

2010 ◽  
Vol 31 (1) ◽  
pp. 70-72 ◽  
Author(s):  
M Ciantelli ◽  
P Ghirri ◽  
S Presi ◽  
E Sigali ◽  
M Vuerich ◽  
...  

PEDIATRICS ◽  
1993 ◽  
Vol 92 (1) ◽  
pp. 135-139
Author(s):  
Hatem Khammash ◽  
Max Perlman ◽  
Julian Wojtulewicz ◽  
Michael Dunn

Objective. In light of the paucity of published data on the use of surfactant in full-term infants with respiratory failure due to meconium aspiration syndrome and respiratory distress syndrome, we report our experience with this therapy. Our goal was to explore possible justification for randomized controlled trials of surfactant treatment in similar patients at an earlier, less severe stage of the disease. Methods. Retrospective consecutive case series of 20 infants with severe meconium aspiration syndrome and 29 infants with severe respiratory distress syndrome who received bovine surfactant between March 1990 and December 1992 in three neonatal intensive care units in a regionalized setting. Outcome of treatment was assessed by comparing changes in several respiratory indices including the oxygenation index, between 4 and 6 hours and 1 and 3 hours before and after the first dose of surfactant. Differences were analyzed using analysis of variance for repeated measures, with treatment and time as co-variates. Results. In the meconium aspiration group the mean oxygenation index decreased from 36 ± 12 at 1 to 3 hours presurfactant to 24 ± 14 at 1 to 3 hours postsurfactant (P < .001). In the patients with respiratory distress syndrome the mean oxygenation index fell from 30 ± 17 at 1 to 3 hours presurfactant to 12 ± 6 at 1 to 3 hours postsurfactant (P = .0001). Three of 20 patients with meconium aspiration syndrome and 3 of 29 patients with respiratory distress syndrome received extracorporeal membrane oxygenation. Conclusions. Surfactant therapy in full-term infants with respiratory failure due to the meconium aspiration and respiratory distress syndromes is often effective in improving gas exchange. A randomized controlled trial of surfactant therapy at an earlier stage in the course of the illness should be performed.


2021 ◽  
Vol 1 (3) ◽  
pp. 414
Author(s):  
Franco Benvenuto ◽  
LuisDiaz Gonzalez ◽  
MaríaCeleste Mansilla ◽  
Adriana Fandiño

PEDIATRICS ◽  
1985 ◽  
Vol 75 (3) ◽  
pp. 617-618
Author(s):  
CARLO CORCHIA ◽  
MARIA RUIU ◽  
MARCELLO ORZALESI

To the Editor.— Osborn et al1 have reported a positive association between breast-feeding and neonatal hyperbilirubinemia in full-term infants. To give further support to the findings of Osborn et al, we wish to report the results of two similar studies that have been completed in two different hospitals. The first study was carried out in the nursery of the Second School of Medicine of Naples.2 Rooming-in was practiced from 9 am to 12 pm, and during the day, breastfed babies were only offered a supplement of 5% dextrose in water when appropriate.


1997 ◽  
Vol 35 (1) ◽  
pp. 286-287 ◽  
Author(s):  
C Alonso-Vega ◽  
N Wauters ◽  
D Vermeylen ◽  
M F Muller ◽  
E Serruys

PEDIATRICS ◽  
1964 ◽  
Vol 33 (6) ◽  
pp. 999-999
Author(s):  
STANTON G. AXLINE ◽  
HAROLD J. SIMON

Studies on the clinical pharmacology of drugs in newborn infants have uncovered a problem of overdosage which may be more common than generally appreciated. Several medicaments are available only in a limited number of highly concentrated formulations. The requirements of premature and full-term newborn infants for very small total dosages necessitate very careful measurements of minute quantities of drug, and overdosage can readily occur. Specifically, Kanamycin is available in only two formulations for injection containing respectively 250 and 333 mg/ml. The dosage of this agent for newborn infants is approximately 8 mg/Kg of body weight 12 hourly.


Sign in / Sign up

Export Citation Format

Share Document