scholarly journals Pharmaceutical Applications of Xanthan Gum in Ophthalmic

2020 ◽  
Vol 8 (1) ◽  
pp. 15-22
Author(s):  
Shiveena Bhatia ◽  
Tarun Kumar ◽  
Sonali Batra ◽  
Sumit Sharma
Keyword(s):  
Xanthan Gum ◽  
Xanthomonas Campestris ◽  
Chemical Modifications ◽  
Limited Volume ◽  
Pharmaceutical Applications ◽  
Drug Loss ◽  
Ophthalmic Delivery ◽  
Mucoadhesive Property ◽  
Stability Issues ◽  
Lacrimal Drainage

Introduction: Ophthalmic delivery system is one of the challenging domains of formulation and development due to tear dilutions, drug loss due to lacrimal drainage, limited volume and pre-corneal barriers. Several pharmaceutical technologies are exploited in order to counter the challenges posed by ocular route such as emulsions and suspensions. But all these technologies have stability issues which lead to their limited use.Background: Among polysaccharides, xanthan gum, a natural occurring biodegradable exopolysaccharide extracted from bacterium Xanthomonas campestris is widely accepted as one of the potential polysaccharide in ophthalmic.Review Results: Xanthan gum is commonly used as an additive to various ophthalmic formulations due to its mucoadhesive property and imparting stability to various novel pharmaceutical technologies for ophthalmic. Xanthan gum also allows chemical modifications with various ligands which consequently allow controlled release, modified dissolution rate and viscoelasticity. Conclusion: In this review we are providing an insight over potential of pharmaceutical applications of xanthan gum. Also, we have discussed the scope of chemical modifications in xanthan gum with modified physicochemical properties.

scholarly journals Genetic and physical analyses of a cluster of genes essential for xanthan gum biosynthesis in Xanthomonas campestris.

1987 ◽  
Vol 169 (6) ◽  
pp. 2854-2861 ◽  
Author(s):  
N E Harding ◽  
J M Cleary ◽  
D K Cabañas ◽  
I G Rosen ◽  
K S Kang
Keyword(s):  
Xanthan Gum ◽  
Xanthomonas Campestris

Xanthan gum produced by Xanthomonas campestris using produced water and crude glycerin as an environmentally friendlier agent to enhance oil recovery

Fuel ◽  
2021 ◽  
pp. 122421
Author(s):  
Elias Ramos de Souza ◽  
Pamela Dias Rodrigues ◽  
Igor C.F. Sampaio ◽  
Edgard Bacic ◽  
Pedro J.L. Crugeira ◽  
...  
Keyword(s):  
Oil Recovery ◽  
Xanthan Gum ◽  
Xanthomonas Campestris ◽  
Produced Water ◽  
Crude Glycerin ◽  
Enhance Oil Recovery

scholarly journals Detection and Visualization of an Exopolysaccharide Produced by Xylella fastidiosa In Vitro and In Planta

2007 ◽  
Vol 73 (22) ◽  
pp. 7252-7258 ◽  
Author(s):  
M. Caroline Roper ◽  
L. Carl Greve ◽  
John M. Labavitch ◽  
Bruce C. Kirkpatrick
Keyword(s):  
Xanthan Gum ◽  
Xanthomonas Campestris ◽  
Polyclonal Antibodies ◽  
Xylella Fastidiosa ◽  
Enzyme Linked Immunosorbent Assay ◽  
In Planta ◽  
Mannose Residue ◽  
Pantoea Stewartii ◽  
Vascular Occlusions

ABSTRACT Many phytopathogenic bacteria, such as Ralstonia solanacearum, Pantoea stewartii, and Xanthomonas campestris, produce exopolysaccharides (EPSs) that aid in virulence, colonization, and survival. EPS can also contribute to host xylem vessel blockage. The genome of Xylella fastidiosa, the causal agent of Pierce's disease (PD) of grapevine, contains an operon that is strikingly similar to the X. campestris gum operon, which is responsible for the production of xanthan gum. Based on this information, it has been hypothesized that X. fastidiosa is capable of producing an EPS similar in structure and composition to xanthan gum but lacking the terminal mannose residue. In this study, we raised polyclonal antibodies against a modified xanthan gum polymer similar to the predicted X. fastidiosa EPS polymer. We used enzyme-linked immunosorbent assay to quantify production of EPS from X. fastidiosa cells grown in vitro and immunolocalization microscopy to examine the distribution of X. fastidiosa EPS in biofilms formed in vitro and in planta and assessed the contribution of X. fastidiosa EPS to the vascular occlusions seen in PD-infected grapevines.

Xanthan gum produced by Xanthomonas campestris from cheese whey: production optimisation and rheological characterisation

2009 ◽  
Vol 89 (14) ◽  
pp. 2440-2445 ◽  
Author(s):  
Michele Mesomo ◽  
Marceli Fernandes Silva ◽  
Gabriela Boni ◽  
Francine Ferreira Padilha ◽  
Marcio Mazutti ◽  
...  
Keyword(s):  
Xanthan Gum ◽  
Xanthomonas Campestris ◽  
Cheese Whey

Functionality of medium molecular weight xanthan gum produced by Xanthomonas Campestris ATCC 1395 in batch culture

2003 ◽  
Vol 36 (5) ◽  
pp. 425-430 ◽  
Author(s):  
A. Kiosseoglou ◽  
E. Papalamprou ◽  
E. Makri ◽  
G. Doxastakis ◽  
V. Kiosseoglou
Keyword(s):  
Molecular Weight ◽  
Batch Culture ◽  
Xanthan Gum ◽  
Xanthomonas Campestris

Production of xanthan gum by Sphingomonas bacteria carrying genes from Xanthomonas campestris

1997 ◽  
Vol 19 (2) ◽  
pp. 92-97 ◽  
Author(s):  
T J Pollock ◽  
M Mikolajczak ◽  
M Yamazaki ◽  
L Thorne ◽  
R W Armentrout
Keyword(s):  
Xanthan Gum ◽  
Xanthomonas Campestris

scholarly journals Genome Sequence of Xanthomonas campestris JX, an Industrially Productive Strain for Xanthan Gum

2012 ◽  
Vol 194 (17) ◽  
pp. 4755-4756 ◽  
Author(s):  
F. Tao ◽  
X. Wang ◽  
C. Ma ◽  
C. Yang ◽  
H. Tang ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Xanthan Gum ◽  
Xanthomonas Campestris
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