scholarly journals Ameliorative Potential of Aminophylline In Restrain Stress Induced Behavioural and Biochemical Alterations

2017 ◽  
Vol 5 (2) ◽  
pp. 117-133
Author(s):  
Rajneet Kaur ◽  
Manjinder Kaur ◽  
Poonam Arora
Keyword(s):  
Oxidative Stress ◽  
Locomotor Activity ◽  
Social Behaviour ◽  
Biochemical Markers ◽  
Immobilization Stress ◽  
Biochemical Alterations ◽  
Behavioural Changes ◽  
Behavioural Patterns ◽  
Therapeutic Doses ◽  
And Oxidative Stress

This study is designed to investigate the attenuating prospective of aminophylline in immobilization stress generated behavioural changes in rats. Animals were exposed to restrain stress before being subjected to varying doses of aminophylline (1mg/kg, 2mg/kg and 4mg/kg). Behavioural changes were analyzed to assess the intensity and the degree of the stress, by estimating the changes in the exploratory behaviour, spontaneous activity and social behaviour using various paradigms. As a consequence of stress, the behavioral patterns so changed were assessed in the terms of changes in the locomotor activity, number of head dips and increased avoidance behaviour. Aminophylline (4mg/kg) modulated the stress produced changes in the behaviour and oxidative stress generated biochemical alterations in a significant manner (p<0.001). The results so obtained suggest that upon exposure to stress, animal behavioural patterns, biochemical markers levels changed and these changes wereefficiently modulated by aminophylline at therapeutic doses.

scholarly journals Studies on Levels of Some Biochemical Markers of Reproduction and Oxidative Stress in Male Partners of Subfertile Couples in a Nigerian Community

2018 ◽  
Vol 150 (suppl_1) ◽  
pp. S66-S67
Author(s):  
Constance Nwadike ◽  
Harrison Nwanjor ◽  
Majesty Duru ◽  
Catherine Onyejiekwe ◽  
Roy Ezekwe
Keyword(s):  
Oxidative Stress ◽  
Biochemical Markers ◽  
Male Partners ◽  
And Oxidative Stress

scholarly journals Effect of transient scrotal hyperthermia on sperm parameters, seminal plasma biochemical markers, and oxidative stress in men

2015 ◽  
Vol 17 (4) ◽  
pp. 668 ◽  
Author(s):  
Wei Xia ◽  
Chang-Hong Zhu ◽  
Meng Rao ◽  
Xiao-Ling Zhao ◽  
Jing Yang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Seminal Plasma ◽  
Biochemical Markers ◽  
Sperm Parameters ◽  
And Oxidative Stress

Biochemical impact of soccer: an analysis of hormonal, muscle damage, and redox markers during the season

2014 ◽  
Vol 39 (4) ◽  
pp. 432-438 ◽  
Author(s):  
João Renato Silva ◽  
António Rebelo ◽  
Franklim Marques ◽  
Laura Pereira ◽  
André Seabra ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Glutathione Reductase ◽  
Muscle Damage ◽  
Muscle Function ◽  
Biochemical Markers ◽  
Reductase Activity ◽  
Recovery Period ◽  
Soccer Players ◽  
Professional Soccer ◽  
And Oxidative Stress

This study aimed to analyze changes in performance, muscle function, and stress-related biochemical markers in professional soccer players (n = 14) at 4 timepoints (3 for performance and 4 for stress-related biochemical markers) during the soccer season [Formula: see text] preseason (E1), midseason (E2), end of the season (E3) [Formula: see text] and after the end of the recovery period (E4). Performance in 5- and 30-m sprints, countermovement jump, and agility, and maximal isokinetic knee extension and knee flexion strength were measured (E1 to E3). We observed increased in-season levels of myoglobin (E2 > E1 and E4; p < 0.05), a higher testosterone/cortisol ratio (T/C), and increased levels of creatine kinase (CK), C-reactive protein, superoxide dismutase (SOD), protein sulfhydryls (–SH), and malondialdehyde (E2 and E3 > E1 and E4; p < 0.05). Lower cortisol concentrations (E3 < E1 and E4; p < 0.05) and glutathione reductase activity (E3 < E2 and E4; p < 0.05) were observed at the end of the season. T/C, CK, SOD, –SH, and malondialdehyde decreased during the off-season, and cortisol and glutathione reductase increased (E3 < E4; p < 0.05). Agility increased in E2 and E3 (p < 0.01). Significant correlations were found during the season between hormonal and muscle function parameters (r = 0.56–0.86; p < 0.05). In addition, in E2, significant associations were observed between match-accumulated time (MATE2; minutes played by each player during the competition period), performance, and hormonal and redox parameters (r = 0.456–0.615; p < 0.05). In conclusion, this study shows that soccer players face significant changes in biomarkers of physiologic strain (muscle damage and oxidative stress-related markers) during the season, but values return to normal during the off-season. Additionally, MAT influences physical, hormonal, and oxidative stress-related parameters in professional soccer players.

Haemato-biochemical alterations and oxidative stress associated with naturally occurring porcine circovirus2 infection in pigs

2020 ◽  
Vol 52 (5) ◽  
pp. 2243-2250
Author(s):  
J. B. Rajesh ◽  
S. Rajkhowa ◽  
U. Dimri ◽  
H. Prasad ◽  
N. H. Mohan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Biochemical Alterations ◽  
Naturally Occurring ◽  
And Oxidative Stress

Antagonistic effects of Spirulina platensis on diazinon-induced hemato-biochemical alterations and oxidative stress in rats

2018 ◽  
Vol 25 (27) ◽  
pp. 27463-27470 ◽  
Author(s):  
Mohamed M. Abdel-Daim ◽  
Abdelrahman Ibrahim Abushouk ◽  
Maha I. Alkhalf ◽  
Eman A. Toraih ◽  
Manal S. Fawzy ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Spirulina Platensis ◽  
Antagonistic Effects ◽  
Biochemical Alterations ◽  
And Oxidative Stress

scholarly journals Fucoidan Protects against Acute Sulfoxaflor-Induced Hematological/Biochemical Alterations and Oxidative Stress in Male Mice

2021 ◽  
Vol 15 (1) ◽  
pp. 16
Author(s):  
Petek Piner Benli ◽  
Merve Kaya ◽  
Yusuf Kenan Dağlıoğlu
Keyword(s):  
Oxidative Stress ◽  
Biochemical Parameters ◽  
Biological Activities ◽  
Hematological Parameters ◽  
Sulfated Polysaccharide ◽  
Protective Role ◽  
Protective Effects ◽  
Biochemical Alterations ◽  
Hematological And Biochemical Parameters ◽  
And Oxidative Stress

Fucoidan is a sulfated polysaccharide which can be found among a number of macroalgea species. It has a broad spectrum of biological activities including anti-oxidant, anti-tumor, immunoregulation, anti-viral and anti-coagulant. The current study was performed to investigate possible protective effects of fucoidan for sulfoxaflor-induced hematological/biochemical alterations and oxidative stress in the blood of male Swiss albino mice. For this purpose, sulfoxaflor was administered at a dose of 15 mg/kg/day (1/50 oral LD50), and fucoidan was administered at a dose of 50 mg/kg/day by oral gavage alone and combined for 24 h and 7 days. Hematological parameters (RBC, HGB, HCT, MCV, MCH, MCHC, Plt, WBC, Neu, Lym and Mon), serum biochemical parameters (AST, ALT, GGT, LDH, BUN, Cre and TBil), and serum oxidative stress/antioxidant markers (8-OHdG, MDA, POC and GSH) were analyzed. The results indicated that sulfoxaflor altered hematological and biochemical parameters and caused oxidative stress in mice; fucoidan ameliorated some hematological and biochemical parameters and exhibited a protective role as an antioxidant against sulfoxaflor-induced oxidative stress.

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