scholarly journals Insulin receptor expression in subcellular fractions of muscular and adipose tissue as the factor of the tissue insulin resistance development in rats under conditions of the high-energy diet

2013 ◽  
Vol 59 (2) ◽  
pp. 59-64 ◽  
Author(s):  
MM Kondro ◽  
◽  
TI Halenova ◽  
MIu Kuznietsova ◽  
OM Savchuk ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Adipose Tissue ◽  
Insulin Receptor ◽  
High Energy ◽  
Subcellular Fractions ◽  
Receptor Expression ◽  
Resistance Development ◽  
Insulin Receptor Expression

scholarly journals Obesity-related hypoxia via miR-128 decreases insulin-receptor expression in human and mouse adipose tissue promoting systemic insulin resistance

EBioMedicine ◽  
2020 ◽  
Vol 59 ◽  
pp. 102912 ◽  
Author(s):  
Biagio Arcidiacono ◽  
Eusebio Chiefari ◽  
Anna Foryst-Ludwig ◽  
Giuseppe Currò ◽  
Giuseppe Navarra ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Adipose Tissue ◽  
Insulin Receptor ◽  
Receptor Expression ◽  
Systemic Insulin Resistance ◽  
Insulin Receptor Expression ◽  
Human And Mouse

Berberine reduces insulin resistance through protein kinase C–dependent up-regulation of insulin receptor expression

Metabolism ◽  
2009 ◽  
Vol 58 (1) ◽  
pp. 109-119 ◽  
Author(s):  
Wei-Jia Kong ◽  
Hao Zhang ◽  
Dan-Qing Song ◽  
Rong Xue ◽  
Wei Zhao ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Insulin Receptor ◽  
Receptor Expression ◽  
Kinase C ◽  
Insulin Receptor Expression

scholarly journals Aberrant insulin receptor expression is associated with insulin resistance and skeletal muscle atrophy in myotonic dystrophies

PLoS ONE ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. e0214254 ◽  
Author(s):  
Laura Valentina Renna ◽  
Francesca Bosè ◽  
Elisa Brigonzi ◽  
Barbara Fossati ◽  
Giovanni Meola ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Skeletal Muscle ◽  
Insulin Receptor ◽  
Muscle Atrophy ◽  
Receptor Expression ◽  
Skeletal Muscle Atrophy ◽  
Insulin Receptor Expression

scholarly journals GPx3 dysregulation impacts adipose tissue insulin receptor expression and sensitivity

JCI Insight ◽  
2020 ◽  
Author(s):  
Robert Hauffe ◽  
Vanessa Stein ◽  
Chantal Chudoba ◽  
Tanina Flore ◽  
Michaela Rath ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Insulin Receptor ◽  
Receptor Expression ◽  
Insulin Receptor Expression

scholarly journals Berberis aristata, Elaeis guineensis and Coffea canephora Extracts Modulate the Insulin Receptor Expression and Improve Hepatic Steatosis in NAFLD Patients: A Pilot Clinical Trial

Nutrients ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 3070
Author(s):  
Valentina Cossiga ◽  
Vincenzo Lembo ◽  
Maria Guarino ◽  
Concetta Tuccillo ◽  
Federica Morando ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Insulin Receptor ◽  
Hepatic Steatosis ◽  
Plant Extracts ◽  
Elaeis Guineensis ◽  
Transient Elastography ◽  
Coffea Canephora ◽  
Receptor Expression ◽  
Model Assessment ◽  
Alcoholic Fatty Liver

Non-alcoholic fatty liver disease (NAFLD) is associated with insulin resistance and diabetes. A reduction in insulin receptor (IR) expression has been reported in these patients. The aims of this study were to evaluate the effects of a mixture of plant extracts consisting of Berberis aristata, Elaeis guineensis and decaffeinated green coffee by Coffea canephora on the improvement of glycaemic profile, through the modulation of IR levels, and of hepatic steatosis in NAFLD patients. Forty-nine patients with a grade of steatosis S1-S2 were randomly allocated to the treatment with plant extracts or placebo for six months. Hepatic steatosis was evaluated using transient elastography with CAP (controlled attenuation parameter). Glucose, insulin, and IR levels were measured in serum samples. At the end of the study, patients treated with plant extracts displayed a significant reduction of serum glucose (p < 0.001), insulin levels (p < 0.01), homeostatic model assessment for insulin resistance (HOMA-IR) index (p < 0.001), and CAP value (p < 0.01) compared to placebo. Moreover, the IR expression was increased significantly in the plant extracts group compared to the placebo group (p < 0.05). The combination of plant extracts increases serum IR levels, determining amelioration of glycemic profile and improvement of hepatic steatosis in NAFLD patients.

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