scholarly journals Studies on the Raynaud's Phenomenon of Occupational Origin : II. The Function of the Autonomic Nervous System and the Cold Pressor Test

Sangyo Igaku ◽  
1967 ◽  
Vol 9 (2) ◽  
pp. 60-63
Author(s):  
Akira OKADA ◽  
Takamasa YAMASHITA ◽  
Akira KATSUTA ◽  
Minoru KASUYA ◽  
Teruo KITAZAWA ◽  
...  
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Raynaud’S Phenomenon ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Raynaud's Phenomenon ◽  
Autonomic Nervous ◽  
Pressor Test

Autonomic nervous system dysfunction in sclerodermic and primary Raynaud’s phenomenon

1999 ◽  
Vol 96 (1) ◽  
pp. 49 ◽  
Author(s):  
Paolo PANCERA ◽  
Stefano SANSONE ◽  
Barbara PRESCIUTTINI ◽  
Luciano MONTAGNA ◽  
Silvia CERÙ ◽  
...  
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Autonomic Nervous System Dysfunction ◽  
Autonomic Nervous ◽  
Primary Raynaud’S Phenomenon

scholarly journals Altered Autonomic Nervous System Reactivity to Pain in Trigeminal Neuralgia

2015 ◽  
Vol 42 (2) ◽  
pp. 125-131 ◽  
Author(s):  
Guillaume Léonard ◽  
Philippe Chalaye ◽  
Philippe Goffaux ◽  
David Mathieu ◽  
Isabelle Gaumond ◽  
...  
Keyword(s):  
Heart Rate ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Trigeminal Neuralgia ◽  
Cold Pressor Test ◽  
Cardiac Activity ◽  
Cold Pressor ◽  
Healthy Controls ◽  
P Values ◽  
Autonomic Nervous

AbstractBackground: In the past two decades, there has been increasing evidence to suggest that trigeminal neuralgia (TN) may be linked to a dysfunction of the autonomic nervous system (ANS). The aim of the present study was to formally test this hypothesis by comparing the reactivity of the ANS to experimental pain in a population of TN patients and healthy controls. Methods: Twelve patients diagnosed with classical TN and 12 healthy controls participated in the study. Cardiac activity was assessed while participants were instructed to rest and again during a cold pressor test (CPT). Heart rate variability analyses were performed off-line to obtain parasympathetic (high-frequency) and sympathetic (low-frequency) indices. Results: At baseline, ANS measures did not differ between healthy controls and TN patients, and both groups showed a similar increase in heart rate during the CPT (all p values >0.05). However, TN patients showed a greater increase in cardiac sympathetic activity and a greater decrease in cardiac parasympathetic activity during CPT compared with healthy controls (all p values <0.05). Importantly, changes in sympathetic reactivity, from baseline to CPT, were negatively associated with the number of pain paroxysms experienced each day by TN patients in the preceding week (r=−.58, p<0.05). Conclusions: These results suggest that TN, like many other short-lasting, unilateral facial pain conditions, is linked to ANS alterations. Future studies are required to determine if the altered ANS response observed in TN patients is a cause or a consequence of TN pain

scholarly journals The Assessment of Autonomic Nervous System Activity Based on Photoplethysmography in Healthy Young Men

2021 ◽  
Vol 12 ◽  
Author(s):  
Binbin Liu ◽  
Zhe Zhang ◽  
Xiaohui Di ◽  
Xiaoni Wang ◽  
Lin Xie ◽  
...  
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Mental Arithmetic ◽  
Cold Pressor Test ◽  
Young Men ◽  
Cold Pressor ◽  
Sympathetic Activation ◽  
Pulse Rate Variability ◽  
Activation Patterns ◽  
Autonomic Nervous

Noninvasive assessment of autonomic nervous system (ANS) activity is of great importance, but the accuracy of the method used, which is primarily based on electrocardiogram-derived heart rate variability (HRV), has long been suspected. We investigated the feasibility of photoplethysmography (PPG) in ANS evaluation. Data of 32 healthy young men under four different ANS activation patterns were recorded: baseline, slow deep breathing (parasympathetic activation), cold pressor test (peripheral sympathetic activation), and mental arithmetic test (cardiac sympathetic activation). We extracted 110 PPG-based features to construct classification models for the four ANS activation patterns. Using interpretable models based on random forest, the main PPG features related to ANS activation were obtained. Results showed that pulse rate variability (PRV) exhibited similar changes to HRV across the different experiments. The four ANS patterns could be better classified using more PPG-based features compared with using HRV or PRV features, for which the classification accuracies were 0.80, 0.56, and 0.57, respectively. Sensitive features of parasympathetic activation included features of nonlinear (sample entropy), frequency, and time domains of PRV. Sensitive features of sympathetic activation were features of the amplitude and frequency domain of PRV of the PPG derivatives. Subsequently, these sensitive PPG-based features were used to fit the improved HRV parameters. The fitting results were acceptable (p &lt; 0.01), which might provide a better method of evaluating ANS activity using PPG.

Effect of cold pressor test on single-breath DLCO in normal subjects

1994 ◽  
Vol 76 (2) ◽  
pp. 750-755 ◽  
Author(s):  
A. Frans ◽  
E. Lampert ◽  
O. Kallay ◽  
B. Nejadnik ◽  
C. Veriter ◽  
...  
Keyword(s):  
Pulmonary Arterial Pressure ◽  
Raynaud’S Phenomenon ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Normal Subjects ◽  
Raynaud's Phenomenon ◽  
Pulmonary Wedge Pressure ◽  
Single Breath ◽  
Pulmonary Arterial ◽  
Wedge Pressure

We hypothesized that the decrease in single-breath diffusing capacity of CO (DLCO) as observed in patients with Raynaud's phenomenon (P.J. Fahey et al. Am. J. Med. 76:263–269, 1984) may be present in normal subjects. Therefore, we examined 31 healthy subjects in two different laboratories. Two series of experiments were performed. In the first series DLCO was measured in 22 volunteers before (twice) and 5, 10, and 30 min after a cold pressor test (CPT), which consisted of immersing both hands in a 12 degrees C water bath for 2 min. In the second series right heart catheterization was performed in nine healthy seated subjects. Cardiac output, mean pulmonary arterial pressure, heart rate, and pulmonary wedge pressure were measured before, during, and 10, 20, and 30 min after the CPT. In every volunteer the CPT induced a decrease in DLCO that was still present 30 min after the test. In the nine catheterized subjects DLCO increased above control values during the CPT and then decreased below control values for 30 min. The CPT had no effect on cardiac output, heart rate, or pulmonary wedge pressure. In contrast, pulmonary arterial pressure and pulmonary vascular resistance increased during the CPT and then became lower than the control values for at least 30 min. In summary, the CPT induced a biphasic evolution of DLCO in normal subjects, being increased during the CPT and decreased after it. Our data are best explained by the West model of the lung. Our data suggest that the pulmonary Raynaud's phenomenon is not specific to patients with primary Raynaud's phenomenon.(ABSTRACT TRUNCATED AT 250 WORDS)

scholarly journals A method to quantify autonomic nervous system function in healthy, able-bodied individuals

2020 ◽  
Author(s):  
Shubham Debnath ◽  
Todd J. Levy ◽  
Mayer Bellehsen ◽  
Rebecca M. Schwartz ◽  
Douglas P. Barnaby ◽  
...  
Keyword(s):  
Heart Rate ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Pupil Diameter ◽  
Electrodermal Activity ◽  
Cold Pressor Test ◽  
Healthy Population ◽  
Individual Response ◽  
Autonomic Nervous ◽  
Organ Systems

AbstractThe autonomic nervous system (ANS), which maintains physiological homeostasis in various organ systems via parasympathetic and sympathetic branches, is altered in common diffuse and focal conditions. Sensitive, quantitative biomarkers could detect changes in ANS function, first here in healthy participants and eventually in patients displaying dysautonomia. This framework combines controlled autonomic testing with feature extraction from physiological responses. Twenty-one individuals were assessed in two morning and two afternoon sessions over two weeks. Each session included five standard clinical tests probing autonomic function: squat test, cold pressor test, diving reflex test, deep breathing, and Valsalva maneuver. Noninvasive sensors captured continuous electrocardiography, blood pressure, breathing, electrodermal activity, and pupil diameter. Heart rate, heart rate variability, mean arterial pressure, electrodermal activity, and pupil diameter responses to the perturbations were extracted, and averages across participants were computed. A template matching algorithm calculated scaling and stretching features that optimally fit the average to an individual response. These features were grouped based on test and modality to derive sympathetic and parasympathetic indices for this healthy population. A significant positive correlation (p = 0.000377) was found between sympathetic amplitude response and body mass index. Additionally, longer duration and larger amplitude sympathetic and longer duration parasympathetic responses occurred in afternoon testing sessions; larger amplitude parasympathetic responses occurred in morning sessions. These results demonstrate the robustness and sensitivity of an algorithmic approach to extract multimodal responses from standard tests. This novel method of quantifying ANS function can be used for early diagnosis, measurement of disease progression, or treatment evaluation.

Cold pressor test protocol to evaluate cardiac autonomic function

2006 ◽  
Vol 31 (3) ◽  
pp. 235-243 ◽  
Author(s):  
Jennifer L Wirch ◽  
Larry A Wolfe ◽  
Tracey L Weissgerber ◽  
Gregory A.L Davies
Keyword(s):  
Nervous System ◽  
Autonomic Function ◽  
Parasympathetic Nervous System ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Cardiac Autonomic Function ◽  
Pressor Test ◽  
Lateral Decubitus ◽  
Sympathetic Nervous ◽  
Frequency Power

The primary objective of this study was to develop a cold pressor test (CPT) protocol to evaluate cardiac autonomic function. Secondary objectives were to assess CPT protocol reliability and to examine gender differences in response to orthostatic stress and the CPT. Healthy, normotensive men and women (n = 12 per group) completed 2 trials on different days in the left lateral decubitus and standing postures and during a 6 min CPT (hand immersion while seated). Measurements included R-R interval, blood pressure, ventilatory responses, spontaneous baroreflex sensitivity, and heart rate variability indices. During the CPT, blood pressure and the sympathetic nervous system (SNS) indicator increased significantly and low-frequency power, high-frequency power (normalized for tidal volume), and the parasympathetic nervous system (PNS) indicator decreased significantly. Standing caused significant increases in the SNS indicator and decreases in the R-R interval in both genders. The PNS indicator was higher in women than in men in the left lateral decubitus posture. The 6 min hand-immersion CPT provoked cardiac sympathetic activation and parasympathetic withdrawal; however, it is best suited to studies with a repeated measures design, as analysis of reliability suggests that responses are highly variable between individuals. Performing the CPT in the left lateral decubitus position may prevent vasovagal responses.Key words: cold pressor test, sympathetic nervous system, parasympathetic nervous system, gender, posture.

Hypothalamic pituitary adrenocortical and sympathetic nervous system responses to the cold pressor test in Alzheimer’s disease

2000 ◽  
Vol 48 (3) ◽  
pp. 247-254 ◽  
Author(s):  
Marcella Pascualy ◽  
Eric C Petrie ◽  
Kayla Brodkin ◽  
Elaine R Peskind ◽  
Charles W Wilkinson ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Nervous System ◽  
Sympathetic Nervous System ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Pressor Test ◽  
Sympathetic Nervous
Sign in / Sign up

Export Citation Format

Share Document