scholarly journals Elevated Blood Pressure, Decreased Heart Rate Variability and Incomplete Blood Pressure Recovery after a 12‐hour Night Shift Work

2008 ◽  
Vol 50 (5) ◽  
pp. 380-386 ◽  
Author(s):  
Ta‐Chen Su ◽  
Lian‐Yu Lin ◽  
Dean Baker ◽  
Peter L. Schnall ◽  
Ming‐Fong Chen ◽  
...  
Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
P. Daniel Patterson ◽  
Leonard S. Weiss ◽  
Matthew D. Weaver ◽  
David D. Salcido ◽  
Samantha E. Opitz ◽  
...  

Abstract Background There is an emerging body of evidence that links exposure to shift work to cardiovascular disease (CVD). The risk of coronary events, such as myocardial infarction, is greater among night shift workers compared to day workers. There is reason to believe that repeated exposure to shift work, especially night shift work, creates alterations in normal circadian patterns of blood pressure (BP) and heart rate variability (HRV) and that these alterations contribute to increased risk of CVD. Recent data suggest that allowing shift workers to nap during night shifts may help to normalize BP and HRV patterns and, over time, reduce the risk of CVD. The risk of CVD related to shift work is elevated for emergency medical services (EMS) shift workers due in part to long-duration shifts, frequent use of night shifts, and a high prevalence of multiple jobs. Methods We will use a randomized crossover trial study design with three study conditions. The targeted population is comprised of EMS clinician shift workers, and our goal enrollment is 35 total participants with an estimated 10 of the 35 enrolled not completing the study protocol or classified as lost to attrition. All three conditions will involve continuous monitoring over 72 h and will begin with a 36-h at-home period, followed by 24 total hours in the lab (including a 12-h simulated night shift), ending with 12 h at home. The key difference between the three conditions is the intra-shift nap. Condition 1 will involve a simulated 12-h night shift with total sleep deprivation. Condition 2 will involve a simulated 12-h night shift and a 30-min nap opportunity. Condition 3 will involve a simulated 12-h night shift with a 2-h nap opportunity. Our primary outcomes of interest include blunted BP dipping and reduced HRV as measured by the standard deviation of the inter-beat intervals of normal sinus beats. Non-dipping status will be defined as sleep hours BP dip of less than 10%. Discussion Our study will address two indicators of cardiovascular health and determine if shorter or longer duration naps during night shifts have a clinically meaningful impact. Trial registration ClinicalTrials.gov NCT04469803. Registered on 9 July 2020


2020 ◽  
Vol 129 (3) ◽  
pp. 459-466
Author(s):  
Julian M. Stewart ◽  
Archana Kota ◽  
Mary Breige O’Donnell-Smith ◽  
Paul Visintainer ◽  
Courtney Terilli ◽  
...  

Significant initial orthostatic hypotension (IOH) occurs in ~50% of postural tachycardia syndrome (POTS) patients and 13% of controls. Heart rate and blood pressure recovery are prolonged in IOH sustaining lightheadedness; IOH is more prevalent and severe in POTS. Altered cerebral blood flow and cardiorespiratory regulation are more prevalent in POTS. Altered heart rate variability and baroreflex gain may cause nearly instantaneous lightheadedness in POTS. IOH alone fails to confer a strong probability of POTS.


Author(s):  
Katsuyuki Murata ◽  
Eiji Yano ◽  
Hideki Hashimoto ◽  
Kanae Karita ◽  
Miwako Dakeishi

2019 ◽  
Author(s):  
YunLei Wang ◽  
Tong Zhang ◽  
YuGe Zhang ◽  
Yan Yu ◽  
Fan Bai ◽  
...  

AbstractObjectiveThe objective was to investigate the effects of shift-work (SW) on the carotid arteries.MethodsThis study used two inverted photoperiods (inverted light:dark [ILD]16:8 and ILD12:12) to create the SW model. We recorded the rhythm and performed serological tests, carotid ultrasound, magnetic resonance imaging, and carotid biopsy.ResultsSW induced elevated blood pressure and increased angiotensin-II, apolipoprotein E, blood glucose, and triglycerides. SW increased the carotid intima-media thickness. SW led to the development of carotid arterial thrombosis, reduced cerebral blood flow, and increased the number of collagen fibers, expression of angiotensin receptor and low-density lipoprotein receptor in the carotid arteries. SW decreased 3-hydroxy-3-methylglutaryl-CoA reductase and nitric oxide. SW induced the atherosclerotic plaque in the aorta. Multiple results of SHR were worse than WKY rats.ConclusionSW can induce metabolic disorders and elevated blood pressure. SW can cause intima-media thickening of the carotid artery and aorta atherosclerosis. SW may result in carotid arterial thrombosis and affect cerebral blood flow. Hypertension can aggravate the adverse effects of SW.


Hypertension ◽  
2012 ◽  
Vol 60 (suppl_1) ◽  
Author(s):  
Hiroshi Kawano ◽  
Mayuko Mineta ◽  
Yuko Gando ◽  
Meiko Asaka ◽  
Mitsuru Higuchi

Introduction ; Although exercise in water is appreciated in rehabilitation for patients with renal disease and obesity individuals with knee joint pain, elevated blood pressure (BP) is also induced by water immersion via water pressure. This elevation of BP in water may lead to incidence of acute heart diseases in rehabilitation exercise. It is important for prevention of such acute event to understand determinants of elevated BP with water immersion. Hypothesis ; We assessed the hypothesis that elevated BP with water immersion is affected by venous volume or baroreflex sensitivity (BRS) as well as age or arterial stiffening, because blood pressure is associated with venous return (contributing cardiac output) or vascular functions. Methods ; Thirty-eight young (21.2 ± 1.7 yrs) and 20 older (65.1 ± 3.2 yrs) men participated in this study. In all subjects, mean BP (oscillometric method), pulse wave velocity adjusted by BP (cardio-ankle vascular index: CAVI), venous volume (by using MRI and plethysmography), and BRS by using valsalva maneuver were measured at resting supine position on land. Furthermore, BP and heart rate at standing position on land and following in water (located surface of water at epigastrium) were determined. Results ; On land, mean BP and CAVI were greater, and BRS was smaller in older men compared with young men. There was no different venous volume between 2 age groups. Change in increased systolic BP with water immersion was greater in older men (127 ± 12 mmHg → 145 ± 18 mmHg; P<0.05) than in young men (118 ± 129 mmHg → 129 ± 10 mmHg; P<0.05) (Interaction; P<0.05). Multiple-regression analysis revealed that the change in increased systolic BP with water immersion were independently associated with CAVI (beta = 0.406), when entering BRS, heart rate, venous volume, and CAVI. Conclusion ; In conclusion, these results of the present study suggests that arterial stiffening may contribute to elevated BP with water immersion, but not BRS or venous volume.


2001 ◽  
Vol 280 (6) ◽  
pp. R1674-R1679 ◽  
Author(s):  
Milos P. Stojiljkovic ◽  
Da Zhang ◽  
Heno F. Lopes ◽  
Christine G. Lee ◽  
Theodore L. Goodfriend ◽  
...  

Evidence suggests lipid abnormalities may contribute to elevated blood pressure, increased vascular resistance, and reduced arterial compliance among insulin-resistant subjects. In a study of 11 normal volunteers undergoing 4-h-long infusions of Intralipid and heparin to raise plasma nonesterified fatty acids (NEFAs), we observed increases of blood pressure. In contrast, blood pressure did not change in these same volunteers during a 4-h infusion of saline and heparin. To better characterize the hemodynamic responses to Intralipid and heparin, another group of 21 individuals, including both lean and obese volunteers, was studied after 3 wk on a controlled diet with 180 mmol sodium/day. Two and four hours after starting the infusions, plasma NEFAs increased by 134 and 111% in those receiving Intralipid and heparin, P < 0.01, whereas plasma NEFAs did not change in the first group of normal volunteers who received saline and heparin. The hemodynamic changes in lean and obese subjects in the second study were similar, and the results were combined. The infusion of Intralipid and heparin induced a significant increase in systolic (13.5 ± 2.1 mmHg) and diastolic (8.0 ± 1.5 mmHg) blood pressure as well as heart rate (9.4 ± 1.4 beats/min). Small and large artery compliance decreased, and systemic vascular resistance rose. These data raise the possibility that lipid abnormalities associated with insulin resistance contribute to the elevated blood pressure and heart rate as well as the reduced vascular compliance observed in subjects with the cardiovascular risk factor cluster.


2013 ◽  
Vol 98 (10) ◽  
pp. 1432-1445 ◽  
Author(s):  
Nicolas Nunn ◽  
Claire H. Feetham ◽  
Jennifer Martin ◽  
Richard Barrett‐Jolley ◽  
Antonius Plagge

2014 ◽  
Vol 72 (3) ◽  
pp. 208-215 ◽  
Author(s):  
Breno Bernardes Souza ◽  
Nayara Mussi Monteze ◽  
Fernando Luiz Pereira de Oliveira ◽  
José Magalhães de Oliveira ◽  
Silvia Nascimento de Freitas ◽  
...  

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